Profen and Trilyte drug interactions - a phase IV clinical study of FDA data


Drug interactions are reported among people who take Profen and Trilyte. Common interactions include renal cancer among females and anxiety among males.

The phase IV clinical study analyzes what interactions people who take Profen and Trilyte have. It is created by eHealthMe based on reports of 14 people who take Profen and Trilyte from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 30, 2022

14 people who take Profen and Trilyte together, and have interactions are studied.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 210,419 Profen users for its effectiveness, alternative drugs and more.

What is Trilyte?

Trilyte has active ingredients of polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride. eHealthMe is studying from 185 Trilyte users for its effectiveness, alternative drugs and more.

Number of Profen and Trilyte reports submitted per year:

Profen and Trilyte drug interactions.

Common Profen and Trilyte drug interactions by gender *:


  1. Renal cancer
  2. Renal mass
  3. Hypertension
  4. Injury
  5. Alcohol withdrawal syndrome
  6. Alopecia
  7. Atrial fibrillation
  8. Bronchitis
  9. Decreased appetite
  10. Dehydration


  1. Anxiety
  2. Asthenia
  3. Renal failure
  4. Tooth loss
  5. Blood cholesterol increased
  6. Chronic kidney disease
  7. Cystitis
  8. Dental caries
  9. Depression
  10. Drug toxicity

Common Profen and Trilyte drug interactions by age *:










  1. Blood cholesterol increased
  2. Cystitis
  3. Dental caries
  4. Depression
  5. Drug toxicity
  6. Hypothyroidism
  7. Osteonecrosis of jaw
  8. Tooth loss
  9. Anxiety
  10. Asthenia


  1. Abdominal pain upper
  2. Cholecystitis chronic
  3. Cholelithiasis
  4. Dizziness
  5. Emotional distress
  6. Gallbladder disorder
  7. Injury
  8. Mental disorder


  1. Chronic kidney disease


  1. Hypertension
  2. Alcohol withdrawal syndrome
  3. Gastritis
  4. Gastrooesophageal reflux disease
  5. Hyperthyroidism
  6. Hyponatraemia
  7. Injury
  8. International normalised ratio increased
  9. Nausea
  10. Palpitations

Common conditions people have *:

  1. Osteoporosis (bones weak and more likely to break): 3 people, 21.43%
  2. Urinary Tract Infection: 2 people, 14.29%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
  4. Infection: 2 people, 14.29%
  5. Cough: 2 people, 14.29%
  6. Oedema (fluid collection in tissue): 2 people, 14.29%
  7. Nausea (feeling of having an urge to vomit): 2 people, 14.29%
  8. Psoriasis (immune-mediated disease that affects the skin): 2 people, 14.29%
  9. Constipation: 1 person, 7.14%
  10. Bone Disorder: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and Trilyte?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Browse all drug interactions of Profen and Trilyte:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Profen interactions:

Browse all interactions between Profen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen and polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride (the active ingredients of Profen and Trilyte, respectively), and Profen and Trilyte (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Profen and Trilyte.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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