Promacta and Ibuprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promacta and Ibuprofen. Common interactions include platelet count decreased among females and cognitive disorder among males.

The phase IV clinical study analyzes what interactions people who take Promacta and Ibuprofen have. It is created by eHealthMe based on reports of 41 people who take Promacta and Ibuprofen from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 18, 2023

41 people who take Promacta and Ibuprofen together, and have interactions are studied.

What is Promacta?

Promacta has active ingredients of eltrombopag olamine. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 16,612 Promacta users for its effectiveness, alternative drugs and more.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 231,258 Ibuprofen users for its effectiveness, alternative drugs and more.

Number of Promacta and Ibuprofen reports submitted per year:

Common Promacta and Ibuprofen drug interactions by gender *:

female:

Platelet count decreased
Malaise
Liver disorder
Pyrexia
Drug ineffective
Fall
Pain in extremity
Tremor
Dizziness
Fluid retention

male:

Cognitive disorder
Joint effusion
Dry mouth
Dry skin
Fatigue
Hospitalisation
Hypersensitivity
Increased tendency to bruise
Nausea
Platelet count decreased

Common Promacta and Ibuprofen drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hospitalisation

30-39:

n/a

40-49:

Abdominal distension
Abdominal pain upper
Anaemia
Confusional state
Diarrhoea
Disturbance in attention
Dry mouth
Dry skin
Fatigue
Nausea

50-59:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Drug ineffective
Liver disorder
Sepsis

60+:

Platelet count decreased
Malaise
Diarrhoea
Drug ineffective
Platelet count increased
Anaemia
Encephalopathy
Influenza
Neutrophil count decreased
Rash maculo-papular

Common conditions people have *:

Sleep Disorder: 5 people, 12.20%
Bleeding Disorders: 5 people, 12.20%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 9.76%
Thrombocytopenia (decrease of platelets in blood): 3 people, 7.32%
Interleukin Level Increased: 3 people, 7.32%
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 3 people, 7.32%
Febrile Neutropenia (fever with reduced white blood cells): 3 people, 7.32%
Diffuse Large B-Cell Lymphoma Refractory (cancer of b cells, a type of white blood cell-relapsed): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

Do you take Promacta and Ibuprofen?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Promacta (16,612 reports)
Ibuprofen (231,258 reports)