Promethazine and Aygestin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported only by a few people who take Promethazine and Aygestin together.
The phase IV clinical study analyzes what interactions people who take Promethazine and Aygestin have. It is created by eHealthMe based on reports of 4 people who take the same drugs from the FDA, and is updated regularly.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
4 people who take Promethazine and Aygestin together, and have interactions are studied.
What is Promethazine?
Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 26,977 Promethazine users for its effectiveness, alternative drugs and more.
What is Aygestin?
Aygestin has active ingredients of norethindrone acetate. It is often used in endometriosis. eHealthMe is studying from 1,054 Aygestin users for its effectiveness, alternative drugs and more.
Number of Promethazine and Aygestin reports submitted per year:

Common Promethazine and Aygestin drug interactions by gender *:
female:
- Acute febrile neutrophilic dermatosis
- Febrile neutropenia
- Neutrophilic panniculitis
- Anaemia
- Ear infection
- Sinusitis
male:
n/a
Common Promethazine and Aygestin drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
- Acute febrile neutrophilic dermatosis
- Febrile neutropenia
- Neutrophilic panniculitis
- Anaemia
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
n/a
* Approximation only. Some reports may have incomplete information.
Do you take Promethazine and Aygestin?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Promethazine (26,977 reports)
- Aygestin (1,054 reports)
Browse all drug interactions of Promethazine and Aygestin:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Promethazine side effects:
- Chronic kidney disease: 2,870 reports
- Acute kidney failure: 1,910 reports
- Fatigue (feeling of tiredness): 1,818 reports
- Pain: 1,726 reports
- Diarrhea: 1,451 reports
- Nausea and vomiting: 1,446 reports
- Stress and anxiety: 1,440 reports
- Headache (pain in head): 1,398 reports
- Drug ineffective: 1,035 reports
Browse all side effects of Promethazine:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Aygestin side effects:
- Breast cancer: 101 reports
Browse all side effects of Aygestin:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Promethazine interactions:
- Promethazine and Gabapentin: 4,952 reports
- Promethazine and Omeprazole: 4,253 reports
- Promethazine and Ondansetron: 4,144 reports
- Promethazine and Nexium: 3,808 reports
- Promethazine and Prednisone: 3,797 reports
- Promethazine and Tramadol: 3,673 reports
- Promethazine and Aspirin: 3,555 reports
- Promethazine and Lisinopril: 3,353 reports
- Promethazine and Furosemide: 2,920 reports
- Promethazine and Pantoprazole: 2,862 reports
Browse all interactions between Promethazine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Aygestin interactions:
- Aygestin and Premarin: 361 reports
- Aygestin and Provera: 314 reports
- Aygestin and Prempro: 238 reports
- Aygestin and Estrace: 165 reports
- Aygestin and Lupron: 160 reports
- Aygestin and Lupron depot: 143 reports
- Aygestin and Cycrin: 129 reports
- Aygestin and Premphase: 120 reports
- Aygestin and Vivelle: 116 reports
- Aygestin and Femhrt: 115 reports
Browse all interactions between Aygestin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on promethazine hydrochloride and norethindrone acetate (the active ingredients of Promethazine and Aygestin, respectively), and Promethazine and Aygestin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Promethazine and Aygestin.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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