Promethegan and Levetiracetam drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Promethegan and Levetiracetam. Common interactions include conjunctivitis among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people who take Promethegan and Levetiracetam have. It is created by eHealthMe based on reports of 18 people who take Promethegan and Levetiracetam from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
18 people who take Promethegan and Levetiracetam together, and have interactions are studied.
What is Promethegan?
Promethegan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 405 Promethegan users for its effectiveness, alternative drugs and more.
What is Levetiracetam?
Levetiracetam has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 60,637 Levetiracetam users for its effectiveness, alternative drugs and more.
Number of Promethegan and Levetiracetam reports submitted per year:

Common Promethegan and Levetiracetam drug interactions by gender *:
female:
- Conjunctivitis
- Hypersensitivity
- Orbital oedema
- Pneumomediastinum
- Pneumothorax
- Sepsis
- Subcutaneous emphysema
male:
- Chronic kidney disease
- Anhedonia
- Dysstasia
- Osteopenia
- Osteoporosis
- Renal disorder
- Rib fracture
- Spinal fracture
- Alcoholic seizure
- Bone disorder
Common Promethegan and Levetiracetam drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Anhedonia
- Anxiety
- Bone density decreased
- Dementia
- Dysstasia
- Emotional distress
- Osteopenia
- Osteoporosis
- Pain
- Renal disorder
40-49:
n/a
50-59:
- Emotional distress
- Pain
- Renal failure
- Bone metabolism disorder
- Alcoholic seizure
- Bone disorder
- Conjunctivitis
- Hypersensitivity
- Orbital oedema
- Pneumomediastinum
60+:
- Anhedonia
- Anxiety
- Chronic kidney disease
- Emotional distress
- Pain
- Renal failure
Common conditions people have *:
- Hiv Infection: 15 people, 83.33%
- Stress And Anxiety: 1 person, 5.56%
- Pain: 1 person, 5.56%
- Insomnia (sleeplessness): 1 person, 5.56%
- Headache (pain in head): 1 person, 5.56%
- Colon Cancer: 1 person, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Promethegan and Levetiracetam?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
- Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
- Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Promethegan (405 reports)
- Levetiracetam (60,637 reports)
Browse all drug interactions of Promethegan and Levetiracetam:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Levetiracetam side effects:
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7,432 reports
- Drug ineffective: 6,092 reports
- Fatigue (feeling of tiredness): 2,576 reports
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2,063 reports
- Drowsiness: 1,815 reports
- Dizziness: 1,781 reports
Browse all side effects of Levetiracetam:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Levetiracetam interactions:
- Levetiracetam and Lamotrigine: 6,562 reports
- Levetiracetam and Valproic acid: 4,986 reports
- Levetiracetam and Lacosamide: 4,346 reports
- Levetiracetam and Carbamazepine: 4,127 reports
- Levetiracetam and Topiramate: 4,126 reports
- Levetiracetam and Clobazam: 3,769 reports
- Levetiracetam and Clonazepam: 3,614 reports
- Levetiracetam and Loraz: 3,300 reports
- Levetiracetam and Gabapentin: 2,885 reports
- Levetiracetam and Omeprazole: 2,676 reports
Browse all interactions between Levetiracetam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on promethazine hydrochloride and levetiracetam (the active ingredients of Promethegan and Levetiracetam, respectively), and Promethegan and Levetiracetam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Promethegan and Levetiracetam.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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