Quillivant xr and Trileptal drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Quillivant xr and Trileptal. Common interactions include stomatitis among females and anger among males.
The phase IV clinical study analyzes what interactions people who take Quillivant xr and Trileptal have. It is created by eHealthMe based on reports of 11 people who take Quillivant xr and Trileptal from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
11 people who take Quillivant xr and Trileptal together, and have interactions are studied.
What is Quillivant xr?
Quillivant xr has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 1,968 Quillivant xr users for its effectiveness, alternative drugs and more.
What is Trileptal?
Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 22,338 Trileptal users for its effectiveness, alternative drugs and more.
Number of Quillivant xr and Trileptal reports submitted per year:

Common Quillivant Xr and Trileptal drug interactions by gender *:
female:
- Stomatitis
- Anger
- Ear infection
- Headache
- Pyrexia
- Contusion
- Erythema infectiosum
- Rash
- Skin exfoliation
- Swelling face
male:
- Anger
- Somnambulism
- Disturbance in attention
- Drug ineffective
- Partial seizures
- Restlessness
- Atypical pneumonia
- Headache
- Hypersensitivity
- Hypersomnia
Common Quillivant Xr and Trileptal drug interactions by age *:
0-1:
n/a
2-9:
- Anger
- Somnambulism
- Partial seizures
- Atypical pneumonia
- Headache
- Hypersensitivity
- Hypersomnia
- Movement disorder
- Somnolence
- Syncope
10-19:
- Anger
- Ear infection
- Headache
- Pyrexia
- Stomatitis
- Abnormal behaviour
- Aggression
- Agitation
- Disturbance in attention
- Oropharyngeal pain
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
n/a
Common conditions people have *:
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 36.36%
- Brain Neoplasm Benign (non-cancerous tumour of brain): 2 people, 18.18%
- Seasonal Allergy (allergic condition due to certain season): 1 person, 9.09%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 9.09%
- Insomnia (sleeplessness): 1 person, 9.09%
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 9.09%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 9.09%
- Atypical Pneumonia (acute respiratory disease marked by high fever and coughing): 1 person, 9.09%
- Asthma: 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Quillivant xr and Trileptal?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
- Yektas ?, Samurcu ND, Tufan AE, "Loss of Eyebrows (Madarosis) After Use of Long-Acting Methylphenidate: Case Report", Journal of Clinical Psychopharmacology, 2017 Aug .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Adak, I., & Coskun, M. , "Symptomatic cholelithiasis associated with combined use of methylphenidate and fluoxetine in an otherwise healthy adolescent girl", Psychiatry and Clinical Psychopharmacology, 2014 Jan .
- Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
- Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
- Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Quillivant xr (1,968 reports)
- Trileptal (22,338 reports)
Browse all drug interactions of Quillivant xr and Trileptal:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Quillivant xr side effects:
- Drug ineffective: 467 reports
- Abnormal behavior: 158 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 128 reports
Browse all side effects of Quillivant xr:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Trileptal side effects:
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1,411 reports
- Fatigue (feeling of tiredness): 1,263 reports
- Drug ineffective: 1,258 reports
- Dizziness: 1,242 reports
- Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 1,191 reports
- Headache (pain in head): 1,121 reports
Browse all side effects of Trileptal:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Trileptal interactions:
- Trileptal and Keppra: 1,987 reports
- Trileptal and Lamictal: 1,745 reports
- Trileptal and Seroquel: 1,584 reports
- Trileptal and Topamax: 1,166 reports
- Trileptal and Neurontin: 1,056 reports
- Trileptal and Klonopin: 1,020 reports
- Trileptal and Abilify: 1,011 reports
- Trileptal and Depakote: 1,010 reports
- Trileptal and Lyrica: 910 reports
- Trileptal and Clonazepam: 855 reports
Browse all interactions between Trileptal and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on methylphenidate hydrochloride and oxcarbazepine (the active ingredients of Quillivant xr and Trileptal, respectively), and Quillivant xr and Trileptal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Quillivant xr and Trileptal.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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