Repatha and Protonix drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Repatha and Protonix. Common interactions include diverticulitis among females and myalgia among males.
The phase IV clinical study analyzes what interactions people who take Repatha and Protonix have. It is created by eHealthMe based on reports of 168 people who take Repatha and Protonix from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
168 people who take Repatha and Protonix together, and have interactions are studied.
What is Repatha?
Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 112,849 Repatha users for its effectiveness, alternative drugs and more.
What is Protonix?
Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 127,294 Protonix users for its effectiveness, alternative drugs and more.
Number of Repatha and Protonix reports submitted per year:

Repatha and Protonix drug interactions by gender *:
Repatha and Protonix drug interactions by age *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Repatha and Protonix?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Common Repatha and Protonix interactions:
- Fatigue (feeling of tiredness): 19 reports
- Muscle aches (muscle pain): 5 reports
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 reports
Browse all drug interactions of Repatha and Protonix:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Repatha side effects:
- Back pain: 5,830 reports
- Muscle aches (muscle pain): 5,454 reports
- Rhinorrhea (watery mucus discharge from the nose): 4,132 reports
- Fatigue (feeling of tiredness): 4,045 reports
- Joint pain: 3,885 reports
Browse all side effects of Repatha:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Protonix side effects:
- Chronic kidney disease: 41,674 reports
- Acute kidney failure: 15,351 reports
- Pain: 6,681 reports
- Fatigue (feeling of tiredness): 6,431 reports
- Breathing difficulty: 5,536 reports
- Diarrhea: 5,532 reports
Browse all side effects of Protonix:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Repatha interactions:
- Repatha and Aspirin: 2,290 reports
- Repatha and Zetia: 1,308 reports
- Repatha and Crestor: 1,150 reports
- Repatha and Plavix: 1,049 reports
- Repatha and Metformin: 885 reports
- Repatha and Lisinopril: 878 reports
- Repatha and Praluent: 860 reports
- Repatha and Amlodipine: 829 reports
- Repatha and Vitamin d: 786 reports
- Repatha and Clopidogrel: 760 reports
Browse all interactions between Repatha and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Protonix interactions:
- Protonix and Nexium: 47,449 reports
- Protonix and Prilosec: 44,471 reports
- Protonix and Prevacid: 42,574 reports
- Protonix and Nexium 24hr: 29,743 reports
- Protonix and Dexilant: 28,649 reports
- Protonix and Prevacid 24 hr: 23,707 reports
- Protonix and Prilosec otc: 23,198 reports
- Protonix and Aspirin: 19,201 reports
- Protonix and Omeprazole: 15,717 reports
- Protonix and Lisinopril: 13,604 reports
Browse all interactions between Protonix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on evolocumab and pantoprazole sodium (the active ingredients of Repatha and Protonix, respectively), and Repatha and Protonix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Repatha and Protonix.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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