Sevoflurane and Metformin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sevoflurane and Metformin. Common interactions include unwanted awareness during anaesthesia among females and renal failure among males.

The phase IV clinical study analyzes what interactions people who take Sevoflurane and Metformin have. It is created by eHealthMe based on reports of 59 people who take Sevoflurane and Metformin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 06, 2022

59 people who take Sevoflurane and Metformin together, and have interactions are studied.

What is Sevoflurane?

Sevoflurane has active ingredients of sevoflurane. eHealthMe is studying from 8,477 Sevoflurane users for its effectiveness, alternative drugs and more.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 405,986 Metformin users for its effectiveness, alternative drugs and more.

Number of Sevoflurane and Metformin reports submitted per year:

Common Sevoflurane and Metformin drug interactions by gender *:

female:

Unwanted awareness during anaesthesia
Acidosis
Cardiac arrest
Metabolic acidosis
Abscess limb
Anxiety
Bronchospasm
Chronic kidney disease
Perirectal abscess
Renal failure

male:

Renal failure
Ventricular tachycardia
Rhabdomyolysis
Stress
Haemodynamic instability
Anhedonia
Cellulitis
Groin abscess
Groin pain
Necrotising fasciitis

Common Sevoflurane and Metformin drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Airway complication of anaesthesia
Endotracheal intubation complication
Wheezing

30-39:

Deep vein thrombosis
Thrombophlebitis superficial

40-49:

Bronchospasm
Cellulitis
Chronic kidney disease
Collapse of lung
Gas gangrene
Groin abscess
Groin pain
Necrotising fasciitis
Nephrogenic anaemia
Oxygen saturation decreased

50-59:

Aphasia
Blood glucose increased
Blood pressure systolic increased
Bronchospasm
Confusion postoperative
Cough
Depressed level of consciousness
Disorientation
Gas gangrene
Haemoglobin decreased

60+:

Renal failure
Cardio-respiratory arrest
Coma
Cyanosis
Emotional distress
Fear
Injury
Malaise
Nausea
Pain

Common conditions people have *:

General Anaesthesia: 12 people, 20.34%
Anaesthesia: 12 people, 20.34%
Type 2 Diabetes: 11 people, 18.64%
Pain: 11 people, 18.64%
High Blood Pressure: 6 people, 10.17%
Neuromuscular Blockade Reversal: 5 people, 8.47%
Hypotension (abnormally low blood pressure): 5 people, 8.47%
Glaucoma (increased fluid pressure in the eye with vision loss): 5 people, 8.47%
Cardiac Disorder: 5 people, 8.47%
Weight Decreased: 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

Do you take Sevoflurane and Metformin?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .