Sevoflurane and Metformin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sevoflurane and Metformin. Common interactions include unwanted awareness during anaesthesia among females and renal failure among males.

The phase IV clinical study analyzes what interactions people who take Sevoflurane and Metformin have. It is created by eHealthMe based on reports of 59 people who take Sevoflurane and Metformin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Dec, 06, 2022

59 people who take Sevoflurane and Metformin together, and have interactions are studied.


What is Sevoflurane?

Sevoflurane has active ingredients of sevoflurane. eHealthMe is studying from 8,477 Sevoflurane users for its effectiveness, alternative drugs and more.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 405,986 Metformin users for its effectiveness, alternative drugs and more.

Number of Sevoflurane and Metformin reports submitted per year:

Sevoflurane and Metformin drug interactions.

Common Sevoflurane and Metformin drug interactions by gender *:

female:

  1. Unwanted awareness during anaesthesia
  2. Acidosis
  3. Cardiac arrest
  4. Metabolic acidosis
  5. Abscess limb
  6. Anxiety
  7. Bronchospasm
  8. Chronic kidney disease
  9. Perirectal abscess
  10. Renal failure

male:

  1. Renal failure
  2. Ventricular tachycardia
  3. Rhabdomyolysis
  4. Stress
  5. Haemodynamic instability
  6. Anhedonia
  7. Cellulitis
  8. Groin abscess
  9. Groin pain
  10. Necrotising fasciitis

Common Sevoflurane and Metformin drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Airway complication of anaesthesia
  2. Endotracheal intubation complication
  3. Wheezing

30-39:

  1. Deep vein thrombosis
  2. Thrombophlebitis superficial

40-49:

  1. Bronchospasm
  2. Cellulitis
  3. Chronic kidney disease
  4. Collapse of lung
  5. Gas gangrene
  6. Groin abscess
  7. Groin pain
  8. Necrotising fasciitis
  9. Nephrogenic anaemia
  10. Oxygen saturation decreased

50-59:

  1. Aphasia
  2. Blood glucose increased
  3. Blood pressure systolic increased
  4. Bronchospasm
  5. Confusion postoperative
  6. Cough
  7. Depressed level of consciousness
  8. Disorientation
  9. Gas gangrene
  10. Haemoglobin decreased

60+:

  1. Renal failure
  2. Cardio-respiratory arrest
  3. Coma
  4. Cyanosis
  5. Emotional distress
  6. Fear
  7. Injury
  8. Malaise
  9. Nausea
  10. Pain

Common conditions people have *:

  1. General Anaesthesia: 12 people, 20.34%
  2. Anaesthesia: 12 people, 20.34%
  3. Type 2 Diabetes: 11 people, 18.64%
  4. Pain: 11 people, 18.64%
  5. High Blood Pressure: 6 people, 10.17%
  6. Neuromuscular Blockade Reversal: 5 people, 8.47%
  7. Hypotension (abnormally low blood pressure): 5 people, 8.47%
  8. Glaucoma (increased fluid pressure in the eye with vision loss): 5 people, 8.47%
  9. Cardiac Disorder: 5 people, 8.47%
  10. Weight Decreased: 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

Do you take Sevoflurane and Metformin?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



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Alternative drugs to, pros and cons of the 2 drugs:

Browse all drug interactions of Sevoflurane and Metformin:

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Common Sevoflurane side effects:

Browse all side effects of Sevoflurane:

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Common Metformin side effects:

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Sevoflurane interactions:

Browse all interactions between Sevoflurane and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Metformin interactions:

Browse all interactions between Metformin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on sevoflurane and metformin hydrochloride (the active ingredients of Sevoflurane and Metformin, respectively), and Sevoflurane and Metformin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Sevoflurane and Metformin.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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