Skyrizi and Isoniazid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Skyrizi and Isoniazid. Common interactions include blood lactic acid increased among females and drug-induced liver injury among males.

The phase IV clinical study analyzes what interactions people who take Skyrizi and Isoniazid have. It is created by eHealthMe based on reports of 13 people who take Skyrizi and Isoniazid from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 08, 2022

13 people who take Skyrizi and Isoniazid together, and have interactions are studied.

What is Skyrizi?

Skyrizi has active ingredients of risankizumab-rzaa. eHealthMe is studying from 9,469 Skyrizi users for its effectiveness, alternative drugs and more.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 18,145 Isoniazid users for its effectiveness, alternative drugs and more.

Number of Skyrizi and Isoniazid reports submitted per year:

Common Skyrizi and Isoniazid drug interactions by gender *:

female:

Blood lactic acid increased
Breast cancer metastatic
Neutrophil count increased
Pain
Pyrexia
Streptococcal sepsis
Radius fracture
Hepatotoxicity
Peripheral swelling
Rosacea

male:

Drug-induced liver injury
Mycobacterium tuberculosis complex test positive
Death
Diffuse large b-cell lymphoma

Common Skyrizi and Isoniazid drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug-induced liver injury

40-49:

n/a

50-59:

Hepatotoxicity
Peripheral swelling
Rosacea
Breast cancer metastatic

60+:

Psoriasis
Mycobacterium tuberculosis complex test positive
Altered state of consciousness
Blood lactic acid increased
Death
Diffuse large b-cell lymphoma
Neutrophil count increased
Pain
Pyrexia
Streptococcal sepsis

Common conditions people have *:

Psoriasis (immune-mediated disease that affects the skin): 13 people, 100.00%
Latent Tuberculosis (hidden tuberculosis): 6 people, 46.15%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 23.08%
Thyroid Diseases: 2 people, 15.38%
High Blood Cholesterol: 2 people, 15.38%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Dyslipidaemia (abnormal amount of lipids): 1 person, 7.69%
Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 1 person, 7.69%
Diabetes: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Skyrizi and Isoniazid?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Ganguly, R. J., Abraham, R. R., Prasad, R., & Rao, B. C, "Hyperglycaemia induced by isoniazid preventive therapy", Journal of Family Medicine and Primary Care, 2018 Jan .