Spironolactone and Nac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Spironolactone and Nac. Common interactions include breast cancer among females and amnesia among males.

The phase IV clinical study analyzes what interactions people who take Spironolactone and Nac have. It is created by eHealthMe based on reports of 11 people who take Spironolactone and Nac from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Dec, 02, 2022

11 people who take Spironolactone and Nac together, and have interactions are studied.


What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 101,935 Spironolactone users for its effectiveness, alternative drugs and more.

What is Nac?

Nac has active ingredients of n - acetyl cysteine. eHealthMe is studying from 539 Nac users for its effectiveness, alternative drugs and more.

Number of Spironolactone and Nac reports submitted per year:

Spironolactone and Nac drug interactions.

Common Spironolactone and Nac drug interactions by gender *:

female:

  1. Breast cancer
  2. Cardiac failure congestive
  3. Constipation
  4. Diabetes mellitus
  5. Facial paralysis
  6. Gastrointestinal disorder
  7. Hepatic cirrhosis
  8. Hepatic encephalopathy
  9. Neuropathy peripheral
  10. Pleural effusion

male:

  1. Amnesia
  2. Dyspepsia
  3. Dysuria
  4. Fatigue
  5. Herpes zoster

Common Spironolactone and Nac drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Depression
  2. Headache
  3. Heart rate increased
  4. Hyperhidrosis
  5. Pain

40-49:

  1. Facial paralysis
  2. Gastrointestinal disorder
  3. Hepatic cirrhosis
  4. Hepatic encephalopathy
  5. Neuropathy peripheral
  6. Pleural effusion
  7. Dizziness
  8. Heart rate increased
  9. Hyperhidrosis
  10. Memory impairment

50-59:

  1. Infusion site pain
  2. Sinusitis

60+:

  1. Dyspepsia
  2. Dysuria
  3. Herpes zoster

Common conditions people have *:

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 27.27%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 27.27%
  3. Depression: 2 people, 18.18%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 18.18%
  5. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 18.18%
  6. Cardiac Failure Congestive: 2 people, 18.18%
  7. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 9.09%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
  9. Fungal Test Positive: 1 person, 9.09%
  10. Fungal Infection: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Spironolactone and Nac?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Browse all drug interactions of Spironolactone and Nac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Spironolactone interactions:

Browse all interactions between Spironolactone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Nac interactions:

Browse all interactions between Nac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone and n - acetyl cysteine (the active ingredients of Spironolactone and Nac, respectively), and Spironolactone and Nac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Spironolactone and Nac.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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