Spravato and Adderall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Spravato and Adderall. Common interactions include speech disorder among females and death among males.

The phase IV clinical study analyzes what interactions people who take Spravato and Adderall have. It is created by eHealthMe based on reports of 52 people who take Spravato and Adderall from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Oct, 01, 2022

52 people who take Spravato and Adderall together, and have interactions are studied.


What is Spravato?

Spravato has active ingredients of esketamine hydrochloride. eHealthMe is studying from 3,990 Spravato users for its effectiveness, alternative drugs and more.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 55,539 Adderall users for its effectiveness, alternative drugs and more.

Number of Spravato and Adderall reports submitted per year:

Spravato and Adderall drug interactions.

Common Spravato and Adderall drug interactions by gender *:

female:

  1. Speech disorder
  2. Accident
  3. Altered visual depth perception
  4. Clumsiness
  5. Feeling drunk
  6. General physical health deterioration
  7. Road traffic accident
  8. Somnolence
  9. Throat irritation
  10. Dissociation

male:

  1. Death
  2. Sedation
  3. Feeling drunk
  4. Aggression
  5. Agitation
  6. Alcoholism
  7. Amnesia
  8. Blood glucose decreased
  9. Cognitive disorder
  10. Drug dependence

Common Spravato and Adderall drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Sedation
  2. Dissociation
  3. Dizziness
  4. Dysarthria
  5. Feeling drunk
  6. Headache
  7. Tremor

30-39:

  1. Death
  2. Intentional self-injury
  3. Panic attack
  4. Dissociation
  5. Hypertension
  6. Anxiety
  7. Blood glucose decreased
  8. Hot flush
  9. Memory impairment
  10. Nausea

40-49:

  1. Speech disorder
  2. Accident
  3. Altered visual depth perception
  4. Clumsiness
  5. Feeling drunk
  6. General physical health deterioration
  7. Road traffic accident
  8. Somnolence
  9. Throat irritation
  10. Weight increased

50-59:

  1. Hypertension
  2. Sedation
  3. Visual impairment
  4. Bedridden
  5. Bipolar disorder
  6. Blood pressure increased
  7. Hallucination
  8. Palpitations
  9. Paralysis
  10. Serotonin syndrome

60+:

  1. Sedation
  2. Dissociation
  3. Mental status changes
  4. Urinary tract infection
  5. Urosepsis
  6. Hypotension

Common conditions people have *:

  1. Depression: 37 people, 71.15%
  2. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 13 people, 25.00%
  3. Stress And Anxiety: 8 people, 15.38%
  4. Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 7.69%
  5. Drowsiness: 4 people, 7.69%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.77%
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

Do you take Spravato and Adderall?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Browse all drug interactions of Spravato and Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Spravato interactions:

Browse all interactions between Spravato and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Adderall interactions:

Browse all interactions between Adderall and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on esketamine hydrochloride and amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Spravato and Adderall, respectively), and Spravato and Adderall (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Spravato and Adderall.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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