St. john's wort and Darvocet drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported only by a few people who take St. john's wort and Darvocet together.
The phase IV clinical study analyzes what interactions people who take St. john's wort and Darvocet have. It is created by eHealthMe based on reports of 3 people who take the same drugs from the FDA, and is updated regularly.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
3 people who take St. john's wort and Darvocet together, and have interactions are studied.
What is St. john's wort?
St. john's wort has active ingredients of st. john's wort. It is often used in depression. eHealthMe is studying from 693 St. john's wort users for its effectiveness, alternative drugs and more.
What is Darvocet?
Darvocet has active ingredients of acetaminophen; propoxyphene hydrochloride. It is often used in pain. eHealthMe is studying from 12,056 Darvocet users for its effectiveness, alternative drugs and more.
Number of St. john's wort and Darvocet reports submitted per year:

Common St. John'S Wort and Darvocet drug interactions by gender *:
female:
- Anhedonia
- Ankle fracture
- Aortic arteriosclerosis
- Arterial insufficiency
- Arterial occlusive disease
- Arteriosclerosis coronary artery
- Arthropathy
- Atelectasis
- Basal cell carcinoma
- Blood urea nitrogen/creatinine ratio increased
male:
- Abdominal pain upper
- Abscess
- Cancer pain
- Cardiomegaly
- Cerebrovascular disorder
- Cervical spinal stenosis
- Chest pain
- Chondromalacia
- Chronic obstructive pulmonary disease
- Cough
Common St. John'S Wort and Darvocet drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Abdominal pain upper
- Abscess
- Cancer pain
- Cardiomegaly
- Cerebrovascular disorder
- Cervical spinal stenosis
- Chest pain
- Chondromalacia
- Chronic obstructive pulmonary disease
- Cough
60+:
n/a
* Approximation only. Some reports may have incomplete information.
Do you take St. john's wort and Darvocet?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- St. john's wort (693 reports)
- Darvocet (12,056 reports)
Browse all drug interactions of St. john's wort and Darvocet:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Darvocet side effects:
- Heart disease: 2,063 reports
- Pain: 1,110 reports
- Stress and anxiety: 732 reports
- Heart attack: 673 reports
Browse all side effects of Darvocet:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Darvocet interactions:
- Darvocet and Darvon: 1,908 reports
- Darvocet and Propoxyphene napsylate and acetaminophen: 1,573 reports
- Darvocet and Prednisone: 899 reports
- Darvocet and Lasix: 868 reports
- Darvocet and Prilosec: 772 reports
- Darvocet and Xanax: 726 reports
- Darvocet and Aspirin: 703 reports
- Darvocet and Synthroid: 650 reports
- Darvocet and Nexium: 648 reports
- Darvocet and Ambien: 624 reports
Browse all interactions between Darvocet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on st. john's wort and acetaminophen; propoxyphene hydrochloride (the active ingredients of St. john's wort and Darvocet, respectively), and St. john's wort and Darvocet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides St. john's wort and Darvocet.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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