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St. john's wort and Promethazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported only by a few people who take St. john's wort and Promethazine together.

The phase IV clinical study analyzes what interactions people who take St. john's wort and Promethazine have. It is created by eHealthMe based on reports of 4 people who take the same drugs from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 08, 2022

4 people who take St. john's wort and Promethazine together, and have interactions are studied.

What is St. john's wort?

St. john's wort has active ingredients of st. john's wort. It is often used in depression. eHealthMe is studying from 692 St. john's wort users for its effectiveness, alternative drugs and more.

What is Promethazine?

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 26,977 Promethazine users for its effectiveness, alternative drugs and more.

Number of St. john's wort and Promethazine reports submitted per year:

St. john's wort and Promethazine drug interactions.

Common St. John'S Wort and Promethazine drug interactions by gender *:

female:

  1. Headache
  2. Muscle spasms
  3. Gallbladder disorder
  4. Hepatotoxicity
  5. Pain
  6. Abdominal pain
  7. Abdominal pain upper
  8. Cholelithiasis
  9. Constipation
  10. Convulsion

male:

n/a

Common St. John'S Wort and Promethazine drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Gallbladder disorder
  2. Pain
  3. Abdominal pain
  4. Cholelithiasis
  5. Convulsion
  6. Drug clearance increased
  7. Drug level decreased

40-49:

n/a

50-59:

  1. Headache
  2. Muscle spasms
  3. Abdominal pain upper
  4. Constipation
  5. Fatigue

60+:

n/a

* Approximation only. Some reports may have incomplete information.

Do you take St. john's wort and Promethazine?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Browse all drug interactions of St. john's wort and Promethazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Promethazine side effects:

Browse all side effects of Promethazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Promethazine interactions:

Browse all interactions between Promethazine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on st. john's wort and promethazine hydrochloride (the active ingredients of St. john's wort and Promethazine, respectively), and St. john's wort and Promethazine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides St. john's wort and Promethazine.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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