Sudafed and Acetylsalicylic acid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sudafed and Acetylsalicylic acid. Common interactions include diarrhoea among females and neuropathy peripheral among males.
The phase IV clinical study analyzes what interactions people who take Sudafed and Acetylsalicylic acid have. It is created by eHealthMe based on reports of 84 people who take Sudafed and Acetylsalicylic acid from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
84 people who take Sudafed and Acetylsalicylic acid together, and have interactions are studied.
What is Sudafed?
Sudafed has active ingredients of pseudoephedrine hydrochloride. It is often used in nasal congestion. eHealthMe is studying from 11,935 Sudafed users for its effectiveness, alternative drugs and more.
What is Acetylsalicylic acid?
Acetylsalicylic acid has active ingredients of aspirin. It is often used in high blood pressure. eHealthMe is studying from 119,615 Acetylsalicylic acid users for its effectiveness, alternative drugs and more.
Number of Sudafed and Acetylsalicylic acid reports submitted per year:

Common Sudafed and Acetylsalicylic Acid drug interactions by gender *:
female:
- Diarrhoea
- Migraine
- Abnormal sleep-related event
- Back disorder
- Blood pressure orthostatic
- Bowel movement irregularity
- Breath holding
- Disturbance in attention
- Eye haemorrhage
- Muscle spasms
male:
- Neuropathy peripheral
- Pain
- Arthritis
- Blood chloride decreased
- Blood sodium decreased
- Bone density decreased
- Carbon dioxide decreased
- Cough
- Dizziness
- Emotional distress
Common Sudafed and Acetylsalicylic Acid drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Blood creatine phosphokinase increased
- Gamma-glutamyltransferase increased
- Body temperature increased
- Cardiac arrest
- Delirium
- Drug screen positive
- Tachycardia
30-39:
- Alopecia
- Myocardial infarction
- Psychological trauma
40-49:
- Pain
- Anhedonia
- Anxiety
- Bone density decreased
- Depression
- Emotional distress
- Osteomalacia
- Osteopenia
- Rib fracture
- Vitamin d deficiency
50-59:
- Cystitis interstitial
- Depressed mood
- Diarrhoea
- Drug ineffective
- Emotional distress
- Fungal infection
- Hand fracture
- Heart rate decreased
- Hyperhidrosis
- Hypoxia
60+:
- Abnormal dreams
- Pain
- Full blood count decreased
- Nausea
- Nerve compression
- Neuropathy peripheral
- Peripheral swelling
- Pneumonia
- Pruritus
- Sleep apnoea syndrome
Common conditions people have *:
- Multiple Myeloma (cancer of the plasma cells): 15 people, 17.86%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 14.29%
- Hypersensitivity: 8 people, 9.52%
- Constipation: 8 people, 9.52%
- Immunodeficiency Common Variable: 6 people, 7.14%
- Stress And Anxiety: 5 people, 5.95%
* Approximation only. Some reports may have incomplete information.
Do you take Sudafed and Acetylsalicylic acid?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Alokaily FA, Alghamdi M, Almalki AS, Alhussaini H, "Aspirin induced leukocytoclastic vasculitis, lower gastrointestinal hemorrhage and acute renal failure (mimicking systemic vasculitis)", Saudi medical journal, 2013 Apr .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Sudafed (11,935 reports)
- Acetylsalicylic acid (119,615 reports)
Browse all drug interactions of Sudafed and Acetylsalicylic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Sudafed side effects:
- Drug ineffective: 865 reports
- Fatigue (feeling of tiredness): 750 reports
- Headache (pain in head): 716 reports
- Dizziness: 598 reports
- Pain: 577 reports
- Insomnia (sleeplessness): 565 reports
- Diarrhea: 516 reports
Browse all side effects of Sudafed:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Acetylsalicylic acid side effects:
- Fatigue (feeling of tiredness): 6,359 reports
- Pain: 5,777 reports
- Breathing difficulty: 5,700 reports
- Drug ineffective: 5,625 reports
- Dizziness: 5,258 reports
- Weakness: 5,250 reports
Browse all side effects of Acetylsalicylic acid:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Sudafed interactions:
- Sudafed and Tylenol: 1,055 reports
- Sudafed and Zyrtec: 969 reports
- Sudafed and Ibu: 886 reports
- Sudafed and Profen: 881 reports
- Sudafed and Ibuprofen: 880 reports
- Sudafed and Aspirin: 856 reports
- Sudafed and Benadryl: 827 reports
- Sudafed and Vitamin d: 790 reports
- Sudafed and Flonase: 785 reports
- Sudafed and Prednisone: 698 reports
Browse all interactions between Sudafed and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Acetylsalicylic acid interactions:
- Acetylsalicylic acid and Metformin: 12,671 reports
- Acetylsalicylic acid and Simvastatin: 12,160 reports
- Acetylsalicylic acid and Furosemide: 12,107 reports
- Acetylsalicylic acid and Omeprazole: 10,960 reports
- Acetylsalicylic acid and Amlodipine: 10,682 reports
- Acetylsalicylic acid and Ramipril: 9,361 reports
- Acetylsalicylic acid and Lisinopril: 9,242 reports
- Acetylsalicylic acid and Pantoprazole: 9,228 reports
- Acetylsalicylic acid and Xarelto: 8,706 reports
- Acetylsalicylic acid and Clopidogrel: 8,653 reports
Browse all interactions between Acetylsalicylic acid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pseudoephedrine hydrochloride and aspirin (the active ingredients of Sudafed and Acetylsalicylic acid, respectively), and Sudafed and Acetylsalicylic acid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Sudafed and Acetylsalicylic acid.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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