Sulfasalazine and Salagen drug interactions - a phase IV clinical study of FDA data


Drug interactions are reported among 37 people who take Sulfasalazine and Salagen. Common interactions include rash among females, and oropharyngeal pain among males.

The phase IV clinical study analyzes what interactions people who take Sulfasalazine and Salagen have. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 26, 2023

37 people who take Sulfasalazine and Salagen together, and have interactions are studied.

What is Sulfasalazine?

Sulfasalazine has active ingredients of sulfasalazine. It is used in rheumatoid arthritis. Currently, eHealthMe is studying from 90,771 Sulfasalazine users.

What is Salagen?

Salagen has active ingredients of pilocarpine hydrochloride. It is used in sjogren syndrome. Currently, eHealthMe is studying from 1,891 Salagen users.

Number of Sulfasalazine and Salagen reports submitted per year:

Sulfasalazine and Salagen drug interactions.

Common Sulfasalazine and Salagen drug interactions by gender *:


  1. Rash
  2. Spinal column injury
  3. Stomach discomfort
  4. Stomatitis
  5. Temporomandibular joint syndrome
  6. Vomiting
  7. Arthralgia
  8. Back pain
  9. Neck pain
  10. Pain in extremity


  1. Oropharyngeal pain
  2. Back pain
  3. Infusion related reaction
  4. Mouth ulceration
  5. Musculoskeletal stiffness
  6. Nausea
  7. Necrotising fasciitis
  8. Oral herpes
  9. Pain in extremity
  10. Pericarditis

Common Sulfasalazine and Salagen drug interactions by age *:










  1. Drug ineffective
  2. Inflammation
  3. Pain


  1. Aspartate aminotransferase increased


  1. Oropharyngeal pain
  2. Diarrhoea
  3. Headache
  4. Back pain
  5. Blood pressure fluctuation
  6. Blood pressure increased
  7. Blood uric acid increased
  8. Dysphonia
  9. Gastroenteritis
  10. Heart rate decreased


  1. Arthralgia
  2. Back pain
  3. Hot flush
  4. Inflammation
  5. Iron deficiency
  6. Musculoskeletal pain
  7. Musculoskeletal stiffness
  8. Neutrophil count decreased
  9. Occult blood
  10. Platelet count increased

Common conditions people have *:

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 8.11%
  2. Dry Mouth: 3 people, 8.11%
  3. Psoriasis (immune-mediated disease that affects the skin): 2 people, 5.41%
  4. Irritable Bowel Syndrome: 2 people, 5.41%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Sulfasalazine and Salagen?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drug side effects by duration, gender and age:

Common Sulfasalazine drug interactions:

Browse interactions between Sulfasalazine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Salagen drug interactions:

Browse interactions between Salagen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on sulfasalazine and pilocarpine hydrochloride (the active ingredients of Sulfasalazine and Salagen, respectively), and Sulfasalazine and Salagen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Sulfasalazine and Salagen.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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