Theophyl and Modafinil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Theophyl and Modafinil. Common interactions include atrial fibrillation among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people who take Theophyl and Modafinil have. It is created by eHealthMe based on reports of 24 people who take Theophyl and Modafinil from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 16, 2022

24 people who take Theophyl and Modafinil together, and have interactions are studied.

What is Theophyl?

Theophyl has active ingredients of theophylline. eHealthMe is studying from 17,648 Theophyl users for its effectiveness, alternative drugs and more.

What is Modafinil?

Modafinil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 17,547 Modafinil users for its effectiveness, alternative drugs and more.

Number of Theophyl and Modafinil reports submitted per year:

Common Theophyl and Modafinil drug interactions by gender *:

female:

Atrial fibrillation
Blood potassium decreased
Drug ineffective
Fall
Fluid retention
Food intolerance
Foot fracture
Peripheral swelling
Pneumonia
Stress

male:

Weight decreased
Cardiac murmur
Blood potassium decreased
Cholelithiasis
Diarrhoea
Hallucination
Respiratory failure
Diabetes mellitus
Nephrolithiasis
Psoriatic arthropathy

Common Theophyl and Modafinil drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Atrial fibrillation
Blood potassium decreased
Drug ineffective
Fluid retention
Food intolerance
Peripheral swelling
Stress
Suicidal ideation
Fall
Foot fracture

60+:

Weight decreased
Abasia
Aspartate aminotransferase increased
Atrial fibrillation
Body height decreased
Bone callus excessive
Cataract
Catheter site haemorrhage
Cellulitis
Clostridium difficile colitis

Common conditions people have *:

Hypersensitivity: 3 people, 12.50%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 12.50%
Stress And Anxiety: 2 people, 8.33%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Theophyl and Modafinil?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .