Tiazac and Advil drug interactions - a phase IV clinical study of FDA data


Drug interactions are reported among 53 people who take Tiazac and Advil. Common interactions include dehydration among females, and burning sensation among males.

The phase IV clinical study analyzes what interactions people who take Tiazac and Advil have. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 28, 2023

53 people who take Tiazac and Advil together, and have interactions are studied.

What is Tiazac?

Tiazac has active ingredients of diltiazem hydrochloride. It is used in high blood pressure. Currently, eHealthMe is studying from 4,656 Tiazac users.

What is Advil?

Advil has active ingredients of ibuprofen. It is used in pain. Currently, eHealthMe is studying from 60,401 Advil users.

Number of Tiazac and Advil reports submitted per year:

Tiazac and Advil drug interactions.

Common Tiazac and Advil drug interactions by gender *:


  1. Dehydration
  2. Faeces discoloured
  3. Myocardial infarction
  4. Nephrolithiasis
  5. Renal failure chronic
  6. Bursitis
  7. Wound infection staphylococcal
  8. Osteoarthritis
  9. Pharyngolaryngeal pain
  10. Renal artery atherosclerosis


  1. Burning sensation
  2. Depression
  3. Back pain
  4. Bladder cancer
  5. Bladder neoplasm
  6. Blister
  7. Blood triglycerides increased
  8. Bradycardia
  9. Brain hypoxia
  10. Bronchitis acute

Common Tiazac and Advil drug interactions by age *:








  1. Bradycardia
  2. Brain hypoxia
  3. Completed suicide
  4. Depressed level of consciousness
  5. Hypotension




  1. Chronic kidney disease
  2. Palpitations
  3. Renal failure


  1. Blood pressure diastolic decreased
  2. Blood pressure fluctuation
  3. Blood pressure systolic increased
  4. Cough
  5. Diarrhoea
  6. Drug ineffective
  7. Dyspnoea
  8. Fatigue
  9. Feeling cold
  10. Heart rate decreased


  1. Cholelithiasis
  2. Myocardial infarction
  3. Wound infection staphylococcal
  4. Pharyngolaryngeal pain
  5. Renal artery atherosclerosis
  6. Renal artery stenosis
  7. Muscle cramp
  8. Oedema peripheral
  9. Aortic valve incompetence
  10. Mitral valve incompetence

Common conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 32 people, 60.38%
  2. Osteoporosis (bones weak and more likely to break): 28 people, 52.83%

* Approximation only. Some reports may have incomplete information.

Do you take Tiazac and Advil?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Drug side effects by duration, gender and age:

Common Tiazac drug interactions:

Browse interactions between Tiazac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Advil drug interactions:

Browse interactions between Advil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diltiazem hydrochloride and ibuprofen (the active ingredients of Tiazac and Advil, respectively), and Tiazac and Advil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Tiazac and Advil.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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