Tigan and Imitrex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tigan and Imitrex. Common interactions include humerus fracture among females and depression among males.
The phase IV clinical study analyzes what interactions people who take Tigan and Imitrex have. It is created by eHealthMe based on reports of 22 people who take Tigan and Imitrex from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
22 people who take Tigan and Imitrex together, and have interactions are studied.
What is Tigan?
Tigan has active ingredients of trimethobenzamide hydrochloride. It is often used in nausea. eHealthMe is studying from 1,870 Tigan users for its effectiveness, alternative drugs and more.
What is Imitrex?
Imitrex has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 17,127 Imitrex users for its effectiveness, alternative drugs and more.
Number of Tigan and Imitrex reports submitted per year:

Common Tigan and Imitrex drug interactions by gender *:
female:
- Humerus fracture
- Hypercalcaemia
- Hyperplasia
- Hypertension
- Hyperventilation
- Hypochondriasis
- Hypotension
- Impaired gastric emptying
- Impaired work ability
- Injection site haemorrhage
male:
- Depression
- Emotional distress
- Oesophageal ulcer
- Oesophagitis
- Blood alkaline phosphatase nos increased
- Blood amylase decreased
- Dehydration
- Drug effect decreased
- Gastrointestinal motility disorder
- Haematocrit decreased
Common Tigan and Imitrex drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Abdominal pain
- Anxiety
- Cholecystitis chronic
- Cholelithiasis
- Emotional distress
- Injury
- Pain
- Dependence
- Fall
- Headache
40-49:
- Drug ineffective
- Injection site pain
- Injection site swelling
50-59:
- Oesophagitis
- Blood alkaline phosphatase nos increased
- Blood amylase decreased
- Dehydration
- Drug effect decreased
- Gastrointestinal motility disorder
- Haematocrit decreased
- Haemoglobin abnormal
- International normalised ratio decreased
- Laboratory test abnormal
60+:
- Abdominal mass
- Affect lability
- Burning sensation
- Butterfly rash
- Cataract
- Choking
- Chorea
- Colonic polyp
- Confusional state
- Contusion
Common conditions people have *:
- Depression: 6 people, 27.27%
- Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 18.18%
- Plantar Fasciitis (painful inflammatory process of the plantar fascia): 4 people, 18.18%
- Joint Pain: 4 people, 18.18%
- High Blood Pressure: 4 people, 18.18%
- High Blood Cholesterol: 4 people, 18.18%
- Headache (pain in head): 4 people, 18.18%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 18.18%
- Diabetes: 4 people, 18.18%
- Parkinson's Disease: 3 people, 13.64%
* Approximation only. Some reports may have incomplete information.
Do you take Tigan and Imitrex?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Browse all drug interactions of Tigan and Imitrex:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Tigan side effects:
- Drowsiness: 253 reports
- Dizziness: 201 reports
- Nausea and vomiting: 177 reports
- Hypotension (abnormally low blood pressure): 176 reports
- Fatigue (feeling of tiredness): 153 reports
- High blood pressure: 131 reports
- Drug ineffective: 128 reports
Browse all side effects of Tigan:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Imitrex side effects:
- Drug ineffective: 3,132 reports
- Headache (pain in head): 1,386 reports
- Migraine (headache): 1,233 reports
- Chest pain: 1,199 reports
- Pain: 1,079 reports
- Nausea and vomiting: 926 reports
Browse all side effects of Imitrex:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Tigan interactions:
- Tigan and Apokyn: 750 reports
- Tigan and Sinemet: 267 reports
- Tigan and Aspirin: 197 reports
- Tigan and Zofran: 148 reports
- Tigan and Tylenol: 131 reports
- Tigan and Rytary: 125 reports
- Tigan and Lasix: 121 reports
- Tigan and Prilosec: 117 reports
- Tigan and Lisinopril: 116 reports
- Tigan and Ambien: 113 reports
Browse all interactions between Tigan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Imitrex interactions:
- Imitrex and Topamax: 1,160 reports
- Imitrex and Ambien: 857 reports
- Imitrex and Synthroid: 807 reports
- Imitrex and Neurontin: 778 reports
- Imitrex and Xanax: 752 reports
- Imitrex and Prednisone: 714 reports
- Imitrex and Zoloft: 685 reports
- Imitrex and Nexium: 675 reports
- Imitrex and Profen: 660 reports
- Imitrex and Prilosec: 659 reports
Browse all interactions between Imitrex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on trimethobenzamide hydrochloride and sumatriptan succinate (the active ingredients of Tigan and Imitrex, respectively), and Tigan and Imitrex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Tigan and Imitrex.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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