Tolbutamide and Clarithromycin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among 4 people who take Tolbutamide and Clarithromycin. Common interactions include cardiac arrest among females, and rhabdomyolysis among males.
The phase IV clinical study analyzes what interactions people who take Tolbutamide and Clarithromycin have. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
4 people who take Tolbutamide and Clarithromycin together, and have interactions are studied.
What is Tolbutamide?
Tolbutamide has active ingredients of tolbutamide. It is used in diabetes. Currently, eHealthMe is studying from 730 Tolbutamide users.
What is Clarithromycin?
Clarithromycin has active ingredients of clarithromycin. It is used in sinusitis. Currently, eHealthMe is studying from 42,604 Clarithromycin users.
Number of Tolbutamide and Clarithromycin reports submitted per year:

Common Tolbutamide and Clarithromycin drug interactions by gender *:
female:
- Cardiac arrest
- Drug dependence
- Nodal arrhythmia
- Supraventricular tachycardia
- Therapeutic agent toxicity
male:
- Rhabdomyolysis
- Alanine aminotransferase increased
- Blood potassium increased
- Blood pressure increased
- Blood sodium decreased
- Blood urea increased
- Body temperature increased
- Brain hypoxia
- Cardiac arrest
- Cholelithiasis
Common Tolbutamide and Clarithromycin drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Chronic kidney disease
- Renal failure
- Renal hypertension
60+:
- Cardiac arrest
- Rhabdomyolysis
- Blood creatinine increased
- Blood potassium increased
- Blood pressure increased
- Blood sodium decreased
- Blood urea increased
- Body temperature increased
- Brain hypoxia
- Cholelithiasis
* Approximation only. Some reports may have incomplete information.
Do you take Tolbutamide and Clarithromycin?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Drug side effects by duration, gender and age:
- Tolbutamide side effects (730 reports)
- Clarithromycin side effects (42,604 reports)
Common Tolbutamide drug interactions:
- Tolbutamide and Metformin: 279 reports
- Tolbutamide and Simvastatin: 127 reports
Browse interactions between Tolbutamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Clarithromycin drug interactions:
- Clarithromycin and Amoxicillin: 5,795 reports
- Clarithromycin and Omeprazole: 4,019 reports
- Clarithromycin and Lansoprazole: 3,296 reports
- Clarithromycin and Prednisolone: 2,974 reports
- Clarithromycin and Furosemide: 2,900 reports
- Clarithromycin and Prednisone: 2,858 reports
- Clarithromycin and Metronidazole: 2,767 reports
- Clarithromycin and Aspirin: 2,401 reports
- Clarithromycin and Acetaminophen: 2,246 reports
- Clarithromycin and Pantoprazole: 2,169 reports
Browse interactions between Clarithromycin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on tolbutamide and clarithromycin (the active ingredients of Tolbutamide and Clarithromycin, respectively), and Tolbutamide and Clarithromycin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Tolbutamide and Clarithromycin.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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