Topamax and Flurbiprofen drug interactions - a phase IV clinical study of FDA data


Drug interactions are reported among 30 people who take Topamax and Flurbiprofen. Common interactions include small intestinal ulcer haemorrhage among females, and constipation among males.

The phase IV clinical study analyzes what interactions people who take Topamax and Flurbiprofen have. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 03, 2023

30 people who take Topamax and Flurbiprofen together, and have interactions are studied.

What is Topamax?

Topamax has active ingredients of topiramate. It is used in migraine. Currently, eHealthMe is studying from 57,368 Topamax users.

What is Flurbiprofen?

Flurbiprofen has active ingredients of flurbiprofen. It is used in rheumatoid arthritis. Currently, eHealthMe is studying from 2,570 Flurbiprofen users.

Number of Topamax and Flurbiprofen reports submitted per year:

Topamax and Flurbiprofen drug interactions.

Common Topamax and Flurbiprofen drug interactions by gender *:


  1. Small intestinal ulcer haemorrhage
  2. Drug hypersensitivity
  3. Dyspnoea
  4. Oedema
  5. Eructation
  6. Eye disorder
  7. Micturition urgency
  8. Oral herpes
  9. Pollakiuria
  10. Systemic lupus erythematosus


  1. Constipation
  2. Decreased appetite
  3. Gastroenteritis
  4. Liver abscess
  5. Myalgia
  6. Shunt infection
  7. Upper respiratory tract infection
  8. Urinary retention

Common Topamax and Flurbiprofen drug interactions by age *:










  1. Anaphylactic reaction
  2. Cough
  3. Drug hypersensitivity
  4. Dyspnoea
  5. Oedema
  6. Affective disorder
  7. Diabetes mellitus inadequate control
  8. Eructation
  9. Hypoglycaemia
  10. Micturition urgency


  1. Uterine spasm
  2. Device expulsion
  3. Deep vein thrombosis
  4. Pulmonary embolism


  1. Anaemia
  2. Sinusitis
  3. Small intestinal ulcer haemorrhage
  4. Oral herpes
  5. Systemic lupus erythematosus
  6. Eye disorder


  1. Fatigue

Common conditions people have *:

  1. Immune System Disorder: 12 people, 40.00%
  2. Immunodeficiency Common Variable: 11 people, 36.67%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 20.00%
  4. Neuralgia (pain in one or more nerves): 4 people, 13.33%
  5. Muscle Spasms (muscle contraction): 4 people, 13.33%
  6. Headache (pain in head): 4 people, 13.33%
  7. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 10.00%
  8. Bipolar Disorder (mood disorder): 3 people, 10.00%
  9. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Topamax and Flurbiprofen?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Drug side effects by duration, gender and age:

Common Topamax drug interactions:

Browse interactions between Topamax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Flurbiprofen drug interactions:

Browse interactions between Flurbiprofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on topiramate and flurbiprofen (the active ingredients of Topamax and Flurbiprofen, respectively), and Topamax and Flurbiprofen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Topamax and Flurbiprofen.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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