Topamax and Peginterferon drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Topamax and Peginterferon. Common interactions include anaemia among females and anaemia among males.
The phase IV clinical study analyzes what interactions people who take Topamax and Peginterferon have. It is created by eHealthMe based on reports of 12 people who take Topamax and Peginterferon from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
12 people who take Topamax and Peginterferon together, and have interactions are studied.
What is Topamax?
Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 55,079 Topamax users for its effectiveness, alternative drugs and more.
What is Peginterferon?
Peginterferon has active ingredients of peginterferon alfa-2a; ribavirin. It is often used in hepatitis c. eHealthMe is studying from 13,679 Peginterferon users for its effectiveness, alternative drugs and more.
Number of Topamax and Peginterferon reports submitted per year:

Common Topamax and Peginterferon drug interactions by gender *:
female:
- Anaemia
- Rash
- Renal failure acute
- Allergic transfusion reaction
- Asthenia
- Blood bilirubin increased
- Chest discomfort
- Convulsion
- Dizziness
- Drug hypersensitivity
male:
- Anaemia
- Ascites
- Nephrolithiasis
- Pathogen resistance
- Pleural effusion
- Pneumonia
- Pyrexia
- Renal failure
- Respiratory distress
- Respiratory failure
Common Topamax and Peginterferon drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anaemia
- Ascites
- Aspergillus test positive
- Coagulopathy
- Device related infection
- Escherichia test positive
- General physical health deterioration
- Hepatic failure
- Multi-organ failure
- Multiple-drug resistance
50-59:
- Anaemia
- Dizziness
- Hypotension
- Infection
- Nausea
- Rash
60+:
- Anaemia
- Fall
- Pubis fracture
- Syncope
Common conditions people have *:
- Headache (pain in head): 2 people, 16.67%
- Nausea (feeling of having an urge to vomit): 2 people, 16.67%
- Hiv Infection: 2 people, 16.67%
- High Blood Pressure: 2 people, 16.67%
- Type 2 Diabetes: 1 person, 8.33%
- Birth Control: 1 person, 8.33%
- Breathing Difficulty: 1 person, 8.33%
- Constipation: 1 person, 8.33%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 8.33%
- Depression: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Topamax and Peginterferon?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
- Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Topamax (55,079 reports)
- Peginterferon (13,679 reports)
Browse all drug interactions of Topamax and Peginterferon:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Topamax side effects:
- Drug ineffective: 3,806 reports
- Headache (pain in head): 3,666 reports
- Fatigue (feeling of tiredness): 3,199 reports
- Pain: 2,850 reports
- Stress and anxiety: 2,584 reports
- Dizziness: 2,506 reports
Browse all side effects of Topamax:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Peginterferon side effects:
- Rashes (redness): 1,860 reports
- Fatigue (feeling of tiredness): 1,236 reports
- Thrombocytopenia (decrease of platelets in blood): 1,193 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 756 reports
- Itching: 750 reports
- Fever: 700 reports
Browse all side effects of Peginterferon:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Topamax interactions:
- Topamax and Cymbalta: 4,159 reports
- Topamax and Gabapentin: 3,813 reports
- Topamax and Synthroid: 3,484 reports
- Topamax and Lyrica: 3,359 reports
- Topamax and Wellbutrin: 3,255 reports
- Topamax and Xyrem: 3,196 reports
- Topamax and Lamictal: 3,189 reports
- Topamax and Vitamin d: 3,106 reports
- Topamax and Seroquel: 3,056 reports
- Topamax and Neurontin: 3,000 reports
Browse all interactions between Topamax and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Peginterferon interactions:
- Peginterferon and Ribavirin: 10,336 reports
- Peginterferon and Vx-950: 1,841 reports
- Peginterferon and Incivek: 1,494 reports
- Peginterferon and Rebetol: 1,448 reports
- Peginterferon and Copegus: 628 reports
- Peginterferon and Victrelis: 550 reports
- Peginterferon and Omeprazole: 279 reports
- Peginterferon and Acetaminophen: 263 reports
- Peginterferon and Urso 250: 261 reports
- Peginterferon and Lopurin: 257 reports
Browse all interactions between Peginterferon and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on topiramate and peginterferon alfa-2a; ribavirin (the active ingredients of Topamax and Peginterferon, respectively), and Topamax and Peginterferon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Topamax and Peginterferon.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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