Tranexamic acid and Naloxone drug interactions - a phase IV clinical study of FDA data


Drug interactions are reported among 48 people who take Tranexamic acid and Naloxone. Common interactions include aplastic anaemia among females, and asthenia among males.

The phase IV clinical study analyzes what interactions people who take Tranexamic acid and Naloxone have. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 03, 2023

48 people who take Tranexamic acid and Naloxone together, and have interactions are studied.

What is Tranexamic acid?

Tranexamic acid has active ingredients of tranexamic acid. It is used in heavy or prolong menstrual bleeding. Currently, eHealthMe is studying from 7,905 Tranexamic acid users.

What is Naloxone?

Naloxone has active ingredients of naloxone hydrochloride. Currently, eHealthMe is studying from 5,693 Naloxone users.

Number of Tranexamic acid and Naloxone reports submitted per year:

Tranexamic acid and Naloxone drug interactions.

Common Tranexamic Acid and Naloxone drug interactions by gender *:


  1. Aplastic anaemia
  2. Pulmonary embolism
  3. Mucosal inflammation
  4. Acute febrile neutrophilic dermatosis
  5. Nausea
  6. Odynophagia
  7. Pancreatitis acute
  8. Vomiting
  9. Aplasia
  10. Bacteraemia


  1. Asthenia
  2. Bone marrow failure
  3. Acute myeloid leukaemia
  4. Pneumonia fungal
  5. Acute pulmonary oedema
  6. Blood osmolarity decreased
  7. Blood sodium decreased
  8. Death
  9. Dyspnoea
  10. Haemoglobin decreased

Common Tranexamic Acid and Naloxone drug interactions by age *:


  1. Bone marrow failure
  2. Febrile neutropenia


  1. Aplastic anaemia
  2. Mucosal inflammation
  3. Aplasia
  4. Bacteraemia
  5. Cerebellar haemorrhage
  6. Cerebrospinal fluid leakage
  7. Coma
  8. Disturbance in attention
  9. Epistaxis
  10. Epstein-barr virus infection


  1. Aplastic anaemia
  2. Acute febrile neutrophilic dermatosis
  3. Nausea
  4. Odynophagia
  5. Pancreatitis acute
  6. Vomiting
  7. Acute pulmonary oedema
  8. Dyspnoea
  9. Hidradenitis
  10. Hip deformity




  1. Torsade de pointes
  2. Ventricular tachycardia
  3. Blood osmolarity decreased
  4. Blood sodium decreased
  5. Death
  6. Haemoglobin decreased
  7. Haemorrhage
  8. Initial insomnia
  9. Mean platelet volume decreased
  10. Red blood cell count decreased






  1. Pulmonary embolism
  2. Asthenia
  3. Pneumonia fungal
  4. Post procedural haemorrhage
  5. Hip fracture
  6. Myelodysplastic syndrome
  7. Cerebrovascular accident
  8. Epistaxis
  9. Headache
  10. Hypophagia

Common conditions people have *:

  1. Nausea (feeling of having an urge to vomit): 18 people, 37.50%
  2. Pain: 17 people, 35.42%
  3. Infection: 14 people, 29.17%
  4. Nausea And Vomiting: 14 people, 29.17%
  5. Injury: 10 people, 20.83%
  6. Sedation: 10 people, 20.83%
  7. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 9 people, 18.75%
  8. Constipation: 5 people, 10.42%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 10.42%
  10. Multiple Myeloma (cancer of the plasma cells): 4 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Tranexamic acid and Naloxone?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drug side effects by duration, gender and age:

Common Tranexamic acid drug interactions:

Browse interactions between Tranexamic acid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Naloxone drug interactions:

Browse interactions between Naloxone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tranexamic acid and naloxone hydrochloride (the active ingredients of Tranexamic acid and Naloxone, respectively), and Tranexamic acid and Naloxone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Tranexamic acid and Naloxone.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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