Vitamin d and Vitamin b12 drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Vitamin d and Vitamin b12. Common interactions include gait disturbance among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people who take Vitamin d and Vitamin b12 have. It is created by eHealthMe based on reports of 31,369 people who take Vitamin d and Vitamin b12 from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
31,369 people who take Vitamin d and Vitamin b12 together, and have interactions are studied.
What is Vitamin d?
Vitamin d has active ingredients of ergocalciferol. It is often used in low vitamin d. eHealthMe is studying from 235,074 Vitamin d users for its effectiveness, alternative drugs and more.
What is Vitamin b12?
Vitamin b12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 99,627 Vitamin b12 users for its effectiveness, alternative drugs and more.
Number of Vitamin d and Vitamin b12 reports submitted per year:

Vitamin d and Vitamin b12 drug interactions by gender *:
Vitamin d and Vitamin b12 drug interactions by age *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Vitamin d and Vitamin b12?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Vitamin d (235,074 reports)
- Vitamin b12 (99,627 reports)
Common Vitamin d and Vitamin b12 interactions:
- Fatigue (feeling of tiredness): 2,618 reports
- Dizziness: 1,997 reports
- Diarrhea: 1,933 reports
- Pain: 1,900 reports
- Weakness: 1,642 reports
- Joint pain: 1,545 reports
- Drug ineffective: 1,522 reports
- Breathing difficulty: 1,279 reports
Browse all drug interactions of Vitamin d and Vitamin b12:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Vitamin d side effects:
- Fatigue (feeling of tiredness): 23,634 reports
- Diarrhea: 15,827 reports
- Headache (pain in head): 14,927 reports
- Drug ineffective: 14,811 reports
- Pain: 13,884 reports
- Weakness: 12,993 reports
- Dizziness: 12,165 reports
- Joint pain: 11,351 reports
Browse all side effects of Vitamin d:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Vitamin b12 side effects:
- Fatigue (feeling of tiredness): 11,136 reports
- Diarrhea: 7,787 reports
- Weakness: 6,535 reports
- Headache (pain in head): 6,311 reports
- Drug ineffective: 6,244 reports
- Pain: 5,877 reports
- Dizziness: 5,808 reports
Browse all side effects of Vitamin b12:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Vitamin d interactions:
- Vitamin d and Aspirin: 44,563 reports
- Vitamin d and Calcium: 40,272 reports
- Vitamin d and Gabapentin: 24,901 reports
- Vitamin d and Prednisone: 24,822 reports
- Vitamin d and Vitamin c: 24,265 reports
- Vitamin d and Omeprazole: 23,671 reports
- Vitamin d and Fish oil: 22,083 reports
- Vitamin d and Lisinopril: 21,958 reports
- Vitamin d and Magnesium: 18,926 reports
Browse all interactions between Vitamin d and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Vitamin b12 interactions:
- Vitamin b12 and Aspirin: 20,671 reports
- Vitamin b12 and Vitamin d3: 15,772 reports
- Vitamin b12 and Calcium: 12,306 reports
- Vitamin b12 and Vitamin c: 11,599 reports
- Vitamin b12 and Gabapentin: 11,536 reports
- Vitamin b12 and Omeprazole: 10,752 reports
- Vitamin b12 and Prednisone: 10,689 reports
- Vitamin b12 and Fish oil: 9,414 reports
- Vitamin b12 and Lisinopril: 9,055 reports
Browse all interactions between Vitamin b12 and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ergocalciferol and cobalamin (the active ingredients of Vitamin d and Vitamin b12, respectively), and Vitamin d and Vitamin b12 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Vitamin d and Vitamin b12.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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