Vitamin d3 and Omega-3 drug interactions - from FDA reports

Drug interactions are reported among people who take Vitamin d3 and Omega-3 together. This study is created by eHealthMe based on reports of 26 people who take Vitamin d3 and Omega-3 from FDA, and is updated regularly.

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On Dec, 20, 2018

26 people who take Vitamin d3, Omega-3 are studied.

Number of reports submitted per year:

Vitamin d3 and Omega-3 drug interactions.

Most common drug interactions over time *:

< 1 month:


1 - 6 months:
  1. Abdominal pain upper
  2. Arthralgia (joint pain)
  3. Oropharyngeal pain
  4. Upper respiratory tract infection
  5. Asthma
  6. Chest pain
  7. Cough
  8. Dyspnoea (difficult or laboured respiration)
  9. Headache (pain in head)
  10. Hepatic steatosis (fatty liver disease)
6 - 12 months:


1 - 2 years:


2 - 5 years:


5 - 10 years:


10+ years:


not specified:
  1. Small cell lung cancer (small cell cancer tumour of lung)
  2. Swelling
  3. Syncope (loss of consciousness with an inability to maintain postural tone)
  4. Nausea (feeling of having an urge to vomit)
  5. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  6. Diarrhoea
  7. Abdominal pain upper
  8. Pain
  9. Weight decreased
  10. Dyspnoea (difficult or laboured respiration)

Most common drug interactions by gender *:

  1. Small cell lung cancer (small cell cancer tumour of lung)
  2. Syncope (loss of consciousness with an inability to maintain postural tone)
  3. Thalamic infarction (tissue death of thalamus part of brain)
  4. Thalamus haemorrhage (bleeding in thalamus)
  5. Thrombocytopenia (decrease of platelets in blood)
  6. Upper respiratory tract infection
  7. Vertigo
  8. Viiith nerve injury
  9. Weight decreased
  10. Weight fluctuation
  1. Fall
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Blood urine present
  4. Death
  5. Diarrhoea
  6. Drug hypersensitivity
  7. Electrocardiogram qt prolonged
  8. Generalised oedema (swelling all over the body)
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Hypotension (abnormally low blood pressure)

Most common drug interactions by age *:







  1. Drug hypersensitivity
  2. Hypertension (high blood pressure)
  3. Hypotension (abnormally low blood pressure)
  4. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  5. Pneumonia
  6. Pulmonary oedema (fluid accumulation in the lungs)
  7. Pulmonary toxicity (side effects on the lungs)
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Thrombocytopenia (decrease of platelets in blood)
  1. Abdominal pain upper
  2. Depressed mood
  3. Diarrhoea
  4. Fatigue (feeling of tiredness)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Hunger
  7. Injection site erythema (redness at injection site)
  8. Injection site extravasation (flow of (blood or lymph) from injection site)
  9. Injection site pain
  10. Injection site pruritus (severe itching at injection site)
  1. Hypersensitivity
  2. Abdominal distension
  3. Abdominal pain upper
  4. Adrenal insufficiency (condition in which the adrenal glands do not produce adequate amounts of steroids)
  5. Anaphylactic reaction (serious allergic reaction)
  6. Blood glucose abnormal
  7. Blood glucose increased
  8. Cholangitis sclerosing (infection and obstruction of bile duct)
  9. Colitis ulcerative (inflammation of colon with ulcer)
  10. Constipation
  1. Chest pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Abdominal pain upper
  4. Alopecia (absence of hair from areas of the body)
  5. Arthralgia (joint pain)
  6. Asthma
  7. Bone pain
  8. Cancer pain
  9. Cough
  10. Headache (pain in head)
  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Diarrhoea
  3. Anaemia (lack of blood)
  4. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  5. Drug administration error
  6. Rectal haemorrhage (bleeding from anus)
  7. Thrombosis (formation of a blood clot inside a blood vessel)
  8. Abdominal discomfort
  9. Abdominal distension
  10. Abnormal behaviour

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

Do you take Vitamin d3 and Omega-3?

You are not alone:

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Browse by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Interactions between Vitamin d3 and drugs from A to Z
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Interactions between Omega-3 and drugs from A to Z
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Browse all drug interactions of Vitamin d3 and Omega-3
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What would happen?

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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