Xeljanz and Synthroid drug interactions - from FDA reports
Drug interactions are reported among people who take Xeljanz and Synthroid together. This study is created by eHealthMe based on reports of 951 people who take Xeljanz and Synthroid from FDA, and is updated regularly.
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951 people who take Xeljanz, Synthroid are studied.
Number of reports submitted per year:

Most common drug interactions over time *:
< 1 month:
- Headache (pain in head)
- Nasopharyngitis (inflammation of the nasopharynx)
- Cough
- Diarrhoea
- Pain
- Arthralgia (joint pain)
- Blood pressure increased
- Condition
- Sinusitis (inflammation of sinus)
- Vomiting
1 - 6 months:
- Fatigue (feeling of tiredness)
- Diarrhoea
- Cough
- Dizziness
- Pyrexia (fever)
- Oropharyngeal pain
- Throat irritation
- Urinary tract infection
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Rhinorrhoea (watery mucus discharge from the nose)
6 - 12 months:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cataract (clouding of the lens inside the eye)
- Disease recurrence
- Dizziness
- Fall
- Kidney infection
- Lower respiratory tract infection
- Muscular weakness (muscle weakness)
- Peripheral swelling
- Platelet count decreased
1 - 2 years:
- Cough
- Arthralgia (joint pain)
- Condition
- Drug ineffective
- Abdominal discomfort
- Blood pressure increased
- Headache (pain in head)
- Herpes zoster
- Tooth abscess (pus formation in tooth)
- Urinary tract infection
2 - 5 years:
- Hepatic enzyme increased
- Back pain
- Blood creatine phosphokinase increased
- Condition
- Constipation
- Dehydration (dryness resulting from the removal of water)
- Delirium (wild excitement)
- Fungal infection
- Hypokinesia (decreased bodily movement)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
5 - 10 years:
- Anaemia (lack of blood)
- Urinary tract infection
- Viral upper respiratory tract infection
10+ years:
n/a
not specified:
- Drug ineffective
- Condition
- Joint swelling
- Arthralgia (joint pain)
- Pain
- Synovitis (inflammation of the synovial membrane)
- Fatigue (feeling of tiredness)
- Herpes zoster
- Blood cholesterol increased
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
Most common drug interactions by gender *:
female:
- Nausea (feeling of having an urge to vomit)
- Weight increased
- Sinusitis (inflammation of sinus)
- Malaise (a feeling of general discomfort or uneasiness)
- Anaemia (lack of blood)
- Cough
- Fall
- Nasopharyngitis (inflammation of the nasopharynx)
- Leukopenia (less number of white blood cells in blood)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
male:
- Drug ineffective
- Insomnia (sleeplessness)
- Myalgia (muscle pain)
- Anaemia of chronic disease
- Blood prolactin decreased
- Blood thyroid stimulating hormone decreased
- Constipation
- Essential hypertension (primary hypertension)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Herpes zoster
Most common drug interactions by age *:
0-1:
n/a
2-9:
10-19:
n/a
20-29:
- Infection
- Neoplasm malignant (cancer tumour)
- Pain
- Swelling
- Drug ineffective
30-39:
- Cardiac arrest
- Acidosis (build-up of carbon dioxide in the blood)
- Memory impairment
- Oxygen saturation decreased
- Nausea (feeling of having an urge to vomit)
- Herpes zoster
- Hypersensitivity
- Infection
- Acne (skin problems that cause pimples)
- Arthralgia (joint pain)
40-49:
- Drug ineffective
- Myalgia (muscle pain)
- Bone erosion
- Gait disturbance
- Synovitis (inflammation of the synovial membrane)
- Condition
- Muscle fatigue (a condition in which muscles cannot exert their normal force)
- Pelvic fracture
- Drug intolerance (drug sensitivity)
- Hypersensitivity
50-59:
- Influenza
- Muscle spasms (muscle contraction)
- Pyrexia (fever)
- Sinusitis (inflammation of sinus)
- Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Pustular psoriasis (raised bumps on the skin that are filled with pus)
- Diarrhoea
- Abdominal pain upper
- Asthenia (weakness)
60+:
- Drug ineffective
- Arthralgia (joint pain)
- Pain in extremity
- Cough
- Diarrhoea
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Nasopharyngitis (inflammation of the nasopharynx)
- Blood cholesterol increased
- Dizziness
- Sinusitis (inflammation of sinus)
* Approximation only. Some reports may have incomplete information.
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Related studies
Xeljanz
Xeljanz has active ingredients of tofacitinib citrate. It is often used in rheumatoid arthritis. (latest outcomes from Xeljanz 57,356 users)
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Browse by gender and age
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Interactions between Xeljanz and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y zInteractions between Synthroid and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all drug interactions of Xeljanz and Synthroid
a b c d e f g h i j k l m n o p q r s t u v w x y zWhat would happen?
Predict new side effects and undetected conditions when you take Xeljanz and Synthroid
FDA reports used in this study
- Want to find out more about the FDA reports used in the study? You can request them from FDA.
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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
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