Zyloprim and Actos drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyloprim and Actos. Common interactions include deep vein thrombosis among females and peripheral sensory neuropathy among males.

The phase IV clinical study analyzes what interactions people who take Zyloprim and Actos have. It is created by eHealthMe based on reports of 74 people who take Zyloprim and Actos from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 30, 2023

74 people who take Zyloprim and Actos together, and have interactions are studied.

What is Zyloprim?

Zyloprim has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 5,022 Zyloprim users for its effectiveness, alternative drugs and more.

What is Actos?

Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 49,111 Actos users for its effectiveness, alternative drugs and more.

Number of Zyloprim and Actos reports submitted per year:

Common Zyloprim and Actos drug interactions by gender *:

female:

Deep vein thrombosis
Difficulty in walking
Hypoaesthesia
Injury
Myocardial infarction
Neuropathy peripheral
Oedema
Pain
Pneumonia
Rash

male:

Peripheral sensory neuropathy
Pneumonitis
Cardiac failure congestive
Dyspnoea
Enterobacter sepsis
Febrile neutropenia
Pseudo lymphoma
Arrhythmia
Ascites
Hyperkalaemia

Common Zyloprim and Actos drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cardiovascular disorder
Chronic kidney disease
Confusional state
Deformity
Disorientation
Dysarthria
Hyperkalaemia
Hyponatraemia
Injury
Lethargy

50-59:

Chronic kidney disease
Nephrogenic anaemia
Renal failure
Tubulointerstitial nephritis
Arrhythmia
Azotaemia
Drug ineffective
Malaise
Palpitations
Tachycardia

60+:

Peripheral sensory neuropathy
Dyspnoea
Diarrhoea
Hilar lymphadenopathy
Hypoglycaemia
Chronic kidney disease
Enterobacter sepsis
Febrile neutropenia
Pseudo lymphoma
Weight increased

Common conditions people have *:

Pain: 9 people, 12.16%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 12.16%
Type 2 Diabetes: 7 people, 9.46%
Hyperlipidaemia (presence of excess lipids in the blood): 6 people, 8.11%
High Blood Pressure: 6 people, 8.11%
Enlarged Prostate: 5 people, 6.76%
Urinary Tract Infection: 4 people, 5.41%
Sleep Disorder: 4 people, 5.41%
Iron Overload: 4 people, 5.41%
Indigestion: 4 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Zyloprim and Actos?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.