A study for a 72 year old woman who takes Amlodipine, Spironolactone, Furosemide, Losartan Potassium - from FDA reports


991 females aged 72 (±5) who take the same drugs are studied. This is a personalized study for a 72 year old female patient who has Systolic Hypertension, Hypertension, Blood Pressure Systolic Abnormal. The study is created by eHealthMe based on reports from FDA.



On Apr, 15, 2018

991 females aged 72 (±5) who take Amlodipine, Spironolactone, Furosemide, Losartan Potassium are studied.


Number of reports submitted per year:

Amlodipine, Spironolactone, Furosemide, Losartan Potassium for a 72-year old woman.

Information of the patient in this study:

  • Age: 72
  • Gender: female
  • Conditions: Systolic Hypertension, Hypertension, Blood Pressure Systolic Abnormal
  • Drugs taken:
    • Amlodipine (amlodipine besylate)
    • Spironolactone (spironolactone)
    • Furosemide (furosemide)
    • Losartan Potassium (losartan potassium)

eHealthMe real world results:

Most common drug interactions over time

< 1 month:
  • Constipation
  • Sepsis (a severe blood infection that can lead to organ failure and death)
  • Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles)
  • Neuropathy peripheral (surface nerve damage)
  • Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  • Lower respiratory tract infection
  • Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  • Back pain
  • Peripheral swelling
  • Abdominal pain
1 - 6 months:
  • Constipation
  • Sepsis (a severe blood infection that can lead to organ failure and death)
  • Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  • Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  • Abdominal pain
  • Lower respiratory tract infection
  • Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles)
  • Breathing difficulty
  • Peripheral swelling
  • Back pain
6 - 12 months:
  • Neuropathy peripheral (surface nerve damage)
  • Spinal column stenosis (narrowing of spinal column)
  • Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles)
  • Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  • Abdominal pain
  • Back pain
  • Lower respiratory tract infection
  • Upper respiratory tract infection
  • Sepsis (a severe blood infection that can lead to organ failure and death)
  • Constipation
1 - 2 years:
  • Back pain
  • Weight increased
  • Abdominal pain
  • Nausea and vomiting
  • Aortic calcification (aortic calcification sign of heart valve disease)
  • Oedema (fluid collection in tissue)
  • Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
  • Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  • Constipation
  • Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles)
2 - 5 years:
  • Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  • Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  • Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  • Cardiac failure acute
  • Pneumonia
  • Haemorrhagic arteriovenous malformation (abnormal connection between the arteries and veins in the brain with bleeding)
  • Cardiogenic shock (inadequate circulation of blood)
  • Pulmonary haemorrhage (acute bleeding from the lung)
  • Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  • Stress cardiomyopathy (stress-induced chronic disease of the heart muscle)
5 - 10 years:
  • Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  • Haemorrhagic arteriovenous malformation (abnormal connection between the arteries and veins in the brain with bleeding)
  • Cardiogenic shock (inadequate circulation of blood)
  • Pulmonary haemorrhage (acute bleeding from the lung)
  • Chest pain
  • Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  • Stress cardiomyopathy (stress-induced chronic disease of the heart muscle)
10+ years:
  • Bradycardia (abnormally slow heart action)
  • Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  • Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  • Sepsis (a severe blood infection that can lead to organ failure and death)
  • Back pain
  • Neuropathy peripheral (surface nerve damage)
  • Hyperkalemia (damage to or disease of the kidney)
  • Constipation
  • Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles)
  • Peripheral swelling
not specified:
  • Breathing difficulty
  • Nausea (feeling of having an urge to vomit)
  • Fatigue (feeling of tiredness)
  • Diarrhea
  • Weakness
  • Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles)
  • Pneumonia
  • Fall
  • Pain
  • Dizziness

Top conditions involved for these people *:

  • Diabetes : 82 people, 8.27%
  • Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 77 people, 7.77%
  • Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 73 people, 7.37%
  • High Blood Cholesterol : 69 people, 6.96%
  • Pain : 68 people, 6.86%

Top co-used drugs for these people *:

  • Metformin (127 people, 12.82%)
  • Aspirin (103 people, 10.39%)
  • Synthroid (97 people, 9.79%)
  • Lipitor (93 people, 9.38%)
  • Plavix (68 people, 6.86%)

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Want to find out more about the FDA reports used in the study? You can request them from FDA.

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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