A study for a 30 year old woman who takes Depakote - from FDA reports


2,345 females aged 30 (±5) who take the same drug are studied. This is a personalized study for a 30 year old female patient who has Bipolar Affective Disorder. The study is created by eHealthMe based on reports from FDA.



On Apr, 25, 2018

2,345 females aged 30 (±5) who take Depakote are studied.


Number of reports submitted per year:

Depakote for a 30-year old woman.

Information of the patient in this study:

  • Age: 30
  • Gender: female
  • Conditions: Bipolar Affective Disorder
  • Drugs taken:
    • Depakote (divalproex sodium)

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

  • Reduced Appetite: 16 (0.68% of females aged 30 (±5) who take the drug)
  • Abdominal Pain: 72 (3.07% of females aged 30 (±5) who take the drug)
  • Nausea And Vomiting: 83 (3.54% of females aged 30 (±5) who take the drug)
  • Fatigue(feeling of tiredness): 112 (4.78% of females aged 30 (±5) who take the drug)

As an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea

As an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea

Most common side effects over time

< 1 month:
  • Nausea (feeling of having an urge to vomit)
  • Nausea and vomiting
  • Fever
  • Drowsiness
  • Confusional state
  • Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  • Confusion
  • Sedation
  • Intentional overdose
  • Rashes (redness)
1 - 6 months:
  • Nausea (feeling of having an urge to vomit)
  • Weight increased
  • Fever
  • Abdominal pain
  • Cytolytic hepatitis (dissolution or destruction of a liver cell)
  • Lymph follicular hypertrophy (an increase in the size of the lymph node follicles)
  • Type 2 diabetes
  • Face oedema (swelling of face)
  • Fatigue (feeling of tiredness)
  • Dizziness
6 - 12 months:
  • Nausea (feeling of having an urge to vomit)
  • Weight increased
  • Drug ineffective
  • Headache (pain in head)
  • Stress and anxiety
  • Hypoaesthesia (reduced sense of touch or sensation)
  • Tachyphrenia (abnormally rapid mental activity)
  • Diabetes mellitus inadequate control
  • Crying
  • Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
1 - 2 years:
  • Type 2 diabetes
  • Muscle aches (muscle pain)
  • Fatigue (feeling of tiredness)
  • Joint pain
  • Constipation
  • Diabetes
  • Nausea (feeling of having an urge to vomit)
  • Weakness
  • Fever
  • Feeling hot and cold
2 - 5 years:
  • Type 2 diabetes
  • Stress and anxiety
  • High blood cholesterol
  • Hyperlipidaemia (presence of excess lipids in the blood)
  • Diabetes
  • Photopsia (presence of perceived flashes of light)
  • Oedema (fluid collection in tissue)
  • Vitreous floaters (spots before the eyes)
  • Nausea (feeling of having an urge to vomit)
  • Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
5 - 10 years:
  • Type 2 diabetes
  • Coronary heart disease (narrowing or blockage of the coronary arteries)
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • High blood pressure
  • Enlarged heart
  • Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  • Type 1 diabetes
  • Hypoaesthesia (reduced sense of touch or sensation)
  • High blood cholesterol
  • Malaise (a feeling of general discomfort or uneasiness)
10+ years:
  • Memory loss
  • Weight increased
  • Hypoglycemia (low blood sugar)
  • Stress and anxiety
  • Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat)
  • Abnormal dreams
  • Scurvy (a disease caused by deficiency of vitamin c, characterized by spongy and bleeding gums, bleeding under the skin, and extreme weakness)
  • Abnormal loss of weight
  • Nausea and vomiting
  • Hepatic atrophy (liver is decreased in size)
not specified:
  • Weight increased
  • Nausea (feeling of having an urge to vomit)
  • Diabetes
  • Fatigue (feeling of tiredness)
  • Type 2 diabetes
  • Stress and anxiety
  • Depression
  • Pain
  • Headache (pain in head)
  • High blood cholesterol

Top conditions involved for these people *:

  • Depression : 208 people, 8.87%
  • Stress And Anxiety : 135 people, 5.76%
  • Pain : 101 people, 4.31%
  • Birth Control : 96 people, 4.09%
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 89 people, 3.80%

Top co-used drugs for these people *:

  • Seroquel (396 people, 16.89%)
  • Zyprexa (284 people, 12.11%)
  • Risperdal (268 people, 11.43%)
  • Klonopin (225 people, 9.59%)
  • Abilify (185 people, 7.89%)

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Want to find out more about the FDA reports used in the study? You can request them from FDA.

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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