A study for a 67 year old woman who takes Methotrexate, Cymbalta, Meloxicam - from FDA reports


2,145 females aged 67 (±5) who take the same drugs are studied. This is a personalized study for a 67 year old female patient who has Depression - Chronic, Rheumatoid Arthritis. The study is created by eHealthMe based on reports from FDA.

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On Dec, 06, 2018

2,145 females aged 67 (±5) who take Methotrexate, Cymbalta, Meloxicam are studied.


Number of reports submitted per year:

Methotrexate, Cymbalta, Meloxicam for a 67-year old woman.

Information of the patient in this study:

  • Age: 67
  • Gender: female
  • Conditions: Depression - Chronic, Rheumatoid Arthritis
  • Drugs taken:
    • Methotrexate (methotrexate sodium)
    • Cymbalta (duloxetine hydrochloride)
    • Meloxicam (meloxicam)

eHealthMe real world results:

Most common drug interactions over time

< 1 month:
  1. Headache (pain in head)
  2. Nausea (feeling of having an urge to vomit)
  3. Head injury
  4. Insomnia (sleeplessness)
  5. Post lumbar puncture syndrome
  6. Animal scratch
  7. Joint swelling
  8. Drowsiness
  9. Post procedural haemorrhage (post procedural bleeding)
  10. Pulse abnormal
1 - 6 months:
  1. Pneumonia
  2. C-reactive protein increased
  3. Rashes (redness)
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Treatment failure
  6. Psychotic disorder
  7. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  8. Enterococcal infection
  9. Fatigue (feeling of tiredness)
  10. Joint pain
6 - 12 months:
  1. Diabetes
  2. Urinary tract infection
  3. Cardiac failure congestive
  4. Psychotic disorder
  5. Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles)
  6. Aseptic necrosis (the death of bone tissue due to a lack of blood supply)
  7. Osteonecrosis of jaw (death of bone of jaw)
  8. Osteomyelitis chronic (long lasting infection of bone marrow)
  9. Palatal disorder
  10. Feeling abnormal
1 - 2 years:
  1. Urinary tract infection
  2. Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles)
  3. Cardiac failure congestive
  4. Diabetes
  5. Aseptic necrosis (the death of bone tissue due to a lack of blood supply)
  6. Osteonecrosis of jaw (death of bone of jaw)
  7. Osteomyelitis chronic (long lasting infection of bone marrow)
  8. Dementia (madness)
  9. Palatal disorder
  10. Chronic kidney disease
2 - 5 years:
  1. Drug ineffective
  2. Drug effect decreased
  3. Drug intolerance (drug sensitivity)
  4. Treatment failure
  5. Urinary tract infection
  6. Breast cancer
  7. Pneumonia
  8. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  9. Fever
  10. Heart attack
5 - 10 years:
  1. Lung neoplasm (tumour of lung)
  2. Fall
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Drug ineffective
  5. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen)
  6. Nosebleed (bleeding from nose)
  7. Coronary heart disease (narrowing or blockage of the coronary arteries)
  8. Arthropathy
  9. Urinary tract infection
  10. Gastric ulcer perforation (stomach hole due to ulcer)
10+ years:
  1. Henoch-schonlein purpura nephritis (inflammation of the blood vessels in the kidney)
  2. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  3. Electrocardiogram t wave abnormal
  4. Meningioma (a diverse set of tumours arising from the meninges)
  5. High blood pressure
  6. Accidental overdose (therapeutic agent)
  7. Osteopenia (a condition where bone mineral density is lower than normal)
  8. Arthropathy
  9. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  10. Ketonuria (ketones in urine)
not specified:
  1. Drug ineffective
  2. Joint pain
  3. Pain in extremity
  4. Fatigue (feeling of tiredness)
  5. Fall
  6. Headache (pain in head)
  7. Breathing difficulty
  8. Rashes (redness)
  9. Nausea (feeling of having an urge to vomit)
  10. High blood pressure

Top conditions involved for these people *:

  1. High Blood Pressure : 238 people, 11.10%
  2. High Blood Cholesterol : 178 people, 8.30%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 151 people, 7.04%
  4. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 142 people, 6.62%
  5. Vitamin Supplementation : 92 people, 4.29%
  6. Osteoporosis (bones weak and more likely to break): 84 people, 3.92%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 79 people, 3.68%
  8. Preventive Health Care : 73 people, 3.40%
  9. Psoriasis (immune-mediated disease that affects the skin): 71 people, 3.31%
  10. Sleep Disorder : 67 people, 3.12%

Top co-used drugs for these people *:

  1. Humira (569 people, 26.53%)
  2. Folic Acid (517 people, 24.10%)
  3. Enbrel (369 people, 17.20%)
  4. Lyrica (222 people, 10.35%)
  5. Vitamin D (197 people, 9.18%)
  6. Prednisone (188 people, 8.76%)
  7. Plaquenil (188 people, 8.76%)
  8. Synthroid (156 people, 7.27%)
  9. Xeljanz (149 people, 6.95%)
  10. Nexium (147 people, 6.85%)

* Some reports may have incomplete information.

FDA reports used in this study

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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