A study for a 54 year old woman who takes Letrozole, Cymbalta - from FDA reports


108 females aged 54 (±5) who take the same drugs are studied. This is a personalized study for a 54 year old female patient who has Breast Cancer, Neuropathy - Peripheral. The study is created by eHealthMe based on reports from FDA.

How to use this study: bring a copy to your health teams to ensure drug risks and benefits are fully discussed and understood.


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On Dec, 06, 2018

108 females aged 54 (±5) who take Letrozole, Cymbalta are studied.


Number of reports submitted per year:

Letrozole, Cymbalta for a 54-year old woman.

Information of the patient in this study:

  • Age: 54
  • Gender: female
  • Conditions: Breast Cancer, Neuropathy - Peripheral
  • Drugs taken:
    • Letrozole (letrozole)
    • Cymbalta (duloxetine hydrochloride)

eHealthMe real world results:

Most common drug interactions over time

< 1 month:
  1. Fever
  2. Urinary tract infection
  3. Joint pain
  4. Post-traumatic stress disorder
  5. Respiratory tract congestion (blockage on respiratory system)
  6. Kidney infection
  7. The flu (the flu is caused by an influenza virus)
  8. Nausea and vomiting
  9. Chills (felling of cold)
  10. Nausea (feeling of having an urge to vomit)
1 - 6 months:
  1. Weight decreased
  2. Breathing difficulty
  3. Fatigue (feeling of tiredness)
  4. General physical health deterioration (weak health status)
  5. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  6. Malignant neoplasm progression (cancer tumour came back)
  7. Nausea and vomiting
  8. Bone pain
  9. Haemoglobin decreased
  10. Constipation
6 - 12 months:
  1. Weight decreased
  2. Breathing difficulty
  3. Fatigue (feeling of tiredness)
  4. General physical health deterioration (weak health status)
  5. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  6. Malignant neoplasm progression (cancer tumour came back)
  7. Nausea and vomiting
  8. Bone pain
  9. Constipation
  10. Nausea (feeling of having an urge to vomit)
1 - 2 years:
n/a
2 - 5 years:
  1. Intervertebral disc degeneration (spinal disc degeneration)
  2. Compression fracture (fracture due to pressure caused by injury)
  3. Tricuspid valve incompetence (inefficient heart valve)
  4. Gliosis (a process leading to scars in the central nervous system)
  5. Upper respiratory tract infection
  6. Cardiotoxicity (damage to the heart muscle)
  7. Malignant neoplasm progression (cancer tumour came back)
  8. Tooth extraction
  9. Hyperbaric oxygen therapy
  10. Pulmonary valve incompetence
5 - 10 years:
n/a
10+ years:
n/a
not specified:
  1. Pain
  2. Fall
  3. Nausea (feeling of having an urge to vomit)
  4. Osteonecrosis of jaw (death of bone of jaw)
  5. Nausea and vomiting
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  7. Injury
  8. Diarrhea
  9. Metastases to lung (cancer spreads to lung)
  10. Haemorrhoids (a swollen vein or group of veins in the region of the anus)

Top conditions involved for these people *:

  1. Metastases To Bone (cancer spreads to bone): 34 people, 31.48%
  2. Pain : 25 people, 23.15%
  3. Multiple Myeloma (cancer of the plasma cells): 15 people, 13.89%
  4. Oedema (fluid collection in tissue): 13 people, 12.04%
  5. Metastasis (spreadable cancer to other organ from origin): 13 people, 12.04%
  6. Insomnia (sleeplessness): 9 people, 8.33%
  7. Breast Cancer Female : 6 people, 5.56%
  8. High Blood Pressure : 5 people, 4.63%
  9. Bone Cancer Metastatic : 5 people, 4.63%
  10. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 4.63%

Top co-used drugs for these people *:

  1. Zometa (54 people, 50.00%)
  2. Aredia (42 people, 38.89%)
  3. Faslodex (38 people, 35.19%)
  4. Xanax (32 people, 29.63%)
  5. Ambien (31 people, 28.70%)
  6. Prozac (29 people, 26.85%)
  7. Celexa (28 people, 25.93%)
  8. Celebrex (28 people, 25.93%)
  9. Lasix (27 people, 25.00%)
  10. Cephalexin (27 people, 25.00%)

* Some reports may have incomplete information.

You are not alone:

What are the drugs?

What are the conditions?



Related studies:

FDA reports used in this study


Recent updates

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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