A study for a 43 year old woman who takes Amitril, Lamotrigine - from FDA reports


152 females aged 43 (±5) who take the same drugs are studied. This is a personalized study for a 43 year old female patient who has Depression, Emotional Disorder. The study is created by eHealthMe based on reports from FDA.

How to use this study: bring a copy to your health teams to ensure drug risks and benefits are fully discussed and understood.


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On Dec, 13, 2018

152 females aged 43 (±5) who take Amitril, Lamotrigine are studied.


Number of reports submitted per year:

Amitril, Lamotrigine for a 43-year old woman.

Information of the patient in this study:

  • Age: 43
  • Gender: female
  • Conditions: Depression, Emotional Disorder
  • Drugs taken:
    • Amitril (amitriptyline hydrochloride)
    • Lamotrigine (lamotrigine)

eHealthMe real world results:

Most common drug interactions over time

< 1 month:
  1. Consciousness - decreased
  2. Acidosis (build-up of carbon dioxide in the blood)
  3. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  4. Fall
  5. Vulvovaginal pain
  6. Fever
  7. Therapeutic agent toxicity (poisoning by ability to cure substance)
  8. Breathing difficulty
  9. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  10. Hypotension (abnormally low blood pressure)
1 - 6 months:
  1. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  2. Conjunctival haemorrhage (bleeding underneath the conjunctiva)
  3. Rashes (redness)
  4. Eye swelling
  5. Nausea (feeling of having an urge to vomit)
  6. Gastritis (inflammation of stomach)
  7. Abdominal pain
  8. Excoriation (to tear or wear off the skin of)
  9. Affective disorder (mental disorder)
  10. Allergy to arthropod bite
6 - 12 months:
  1. Head injury
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Therapeutic response unexpected
  4. Pre-existing condition improved
  5. Petit mal epilepsy (absence seizure)
1 - 2 years:
  1. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  2. Influenza like illness
  3. Erythema multiforme (a type of hypersensitivity reaction)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Rashes (redness)
  6. Skin exfoliation (removal of the oldest dead skin cells)
  7. Haemorrhage (bleeding)
  8. Genital discomfort
  9. Urination - painful
  10. Pre-existing condition improved
2 - 5 years:
  1. Antisocial behavior
  2. Psychotic disorder
  3. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  4. Loss of consciousness
  5. Hallucination, visual (seeing things that aren't there)
  6. Injury
  7. Faecal incontinence (a lack of control over passing stool)
5 - 10 years:
  1. Blood amylase increased
  2. Gamma-glutamyltransferase increased
  3. Hepatic enzyme abnormal
  4. Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
  5. Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
  6. Therapeutic agent toxicity (poisoning by ability to cure substance)
  7. Liver disorder (liver diseases)
  8. Blood lactate dehydrogenase increased
  9. Blood phosphorus increased
  10. Blood calcium decreased
10+ years:
  1. Completed suicide (act of taking one's own life)
  2. Abnormal behavior
  3. Stress and anxiety
  4. Abdominal discomfort
  5. Dry mouth
  6. Thirst - excessive
  7. Feeling abnormal
  8. Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat)
  9. Nausea (feeling of having an urge to vomit)
not specified:
  1. Nausea (feeling of having an urge to vomit)
  2. Rashes (redness)
  3. Headache (pain in head)
  4. Nausea and vomiting
  5. Fatigue (feeling of tiredness)
  6. Drowsiness
  7. Stress and anxiety
  8. Pain
  9. Diarrhea
  10. Drug ineffective

Top conditions involved for these people *:

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 12.50%
  2. Stress And Anxiety : 12 people, 7.89%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 7.24%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 10 people, 6.58%
  5. Migraine (headache): 9 people, 5.92%
  6. Partial Seizures (seizures which affect only a part of the brain at onset): 9 people, 5.92%
  7. Pain : 8 people, 5.26%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 4.61%
  9. Headache (pain in head): 6 people, 3.95%
  10. Sleep Disorder : 6 people, 3.95%

Top co-used drugs for these people *:

  1. Seroquel (21 people, 13.82%)
  2. Xyrem (21 people, 13.82%)
  3. Lyrica (19 people, 12.50%)
  4. Oxycontin (18 people, 11.84%)
  5. Neurontin (16 people, 10.53%)
  6. Klonopin (16 people, 10.53%)
  7. Effexor (15 people, 9.87%)
  8. Xanax (15 people, 9.87%)
  9. Zyprexa (13 people, 8.55%)
  10. Benadryl (13 people, 8.55%)

* Some reports may have incomplete information.

You are not alone:

What are the drugs?

What are the conditions?



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FDA reports used in this study


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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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