A study for a 59 year old woman who takes Janumet, Paracetamol, Actemra - from FDA reports


345 females aged 59 (±5) who take the same drugs are studied. This is a personalized study for a 59 year old female patient who has Diabetes, Pain, Still's Disease - Adult. The study is created by eHealthMe based on reports from FDA.

How to use this study: bring a copy to your health teams to ensure drug risks and benefits are fully discussed and understood.


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On Jan, 21, 2019

345 females aged 59 (±5) who take Janumet, Paracetamol, Actemra are studied.


Number of reports submitted per year:

Janumet, Paracetamol, Actemra for a 59-year old woman.

Information of the patient in this study:

  • Age: 59
  • Gender: female
  • Conditions: Diabetes, Pain, Still's Disease - Adult
  • Drugs taken:
    • Janumet (metformin hydrochloride; sitagliptin phosphate)
    • Paracetamol (acetaminophen)
    • Actemra (tocilizumab)

eHealthMe real world results:

Most common drug interactions over time

< 1 month:
  1. Infusion related reaction
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Swelling
  4. Chest pain
  5. Skin ulcer
  6. Joint swelling
  7. Itching
  8. Hair loss
  9. Hypotension (abnormally low blood pressure)
  10. Chills (felling of cold)
1 - 6 months:
  1. Joint pain
  2. Fatigue (feeling of tiredness)
  3. Infusion related reaction
  4. Breathing difficulty
  5. Weight increased
  6. The flu (the flu is caused by an influenza virus)
  7. Nausea (feeling of having an urge to vomit)
  8. Drug ineffective
  9. Chest pain
  10. Hyperhidrosis (abnormally increased sweating)
6 - 12 months:
  1. Joint pain
  2. Joint swelling
  3. Infusion related reaction
  4. Weight increased
  5. High blood pressure
  6. Renal disorder (kidney disease)
  7. Respiratory tract infection
  8. Cystitis noninfective (non-infectious inflammation of the wall of the bladder)
  9. The flu (the flu is caused by an influenza virus)
  10. Fatigue (feeling of tiredness)
1 - 2 years:
  1. Heart attack
  2. Drug ineffective
  3. Infusion related reaction
  4. Wound
  5. Drug effect decreased
  6. Weight increased
  7. Glomerular filtration rate decreased
  8. Alanine aminotransferase increased
  9. Emotional distress
  10. Fatigue (feeling of tiredness)
2 - 5 years:
  1. Fall
  2. Pain in extremity
  3. Joint pain
  4. High blood pressure
  5. Tooth disorder (tooth disease)
  6. Spinal column stenosis (narrowing of spinal column)
  7. Weight decreased
  8. Weight increased
  9. Muscle rupture (tear in muscle)
  10. Joint swelling
5 - 10 years:
  1. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  2. Fatigue (feeling of tiredness)
  3. Arthropathy
  4. Drug ineffective
  5. Cuts and puncture wounds
  6. Skin atrophy (wasting of skin)
  7. Limb injury
  8. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  9. Abdominal abscess (collection of pus in abdomen)
  10. Diverticular perforation (serious gastrointestinal condition in which the intestine's walls are perforated)
10+ years:
n/a
not specified:
  1. Drug ineffective
  2. Joint pain
  3. Fatigue (feeling of tiredness)
  4. High blood pressure
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Pain in extremity
  7. Weight increased
  8. Heart attack
  9. Infusion related reaction
  10. Nasopharyngitis (inflammation of the nasopharynx)

Top conditions involved for these people *:

  1. High Blood Pressure : 35 people, 10.14%
  2. Depression : 13 people, 3.77%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 12 people, 3.48%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 11 people, 3.19%
  5. High Blood Cholesterol : 11 people, 3.19%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 3.19%
  7. Preventive Health Care : 8 people, 2.32%
  8. Osteoporosis (bones weak and more likely to break): 7 people, 2.03%
  9. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 6 people, 1.74%
  10. Insomnia (sleeplessness): 6 people, 1.74%

Top co-used drugs for these people *:

  1. Methotrexate (94 people, 27.25%)
  2. Rituxan (78 people, 22.61%)
  3. Enbrel (77 people, 22.32%)
  4. Plaquenil (71 people, 20.58%)
  5. Orencia (66 people, 19.13%)
  6. Arava (62 people, 17.97%)
  7. Simponi (54 people, 15.65%)
  8. Folic Acid (47 people, 13.62%)
  9. Prednisone (44 people, 12.75%)
  10. Synthroid (39 people, 11.30%)

* Some reports may have incomplete information.

You are not alone:

What are the drugs?

What are the conditions?



Related studies:

FDA reports used in this study


Recent updates

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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