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A study for a 60 year old woman who takes Elavil, Synthroid, Xeljanz - from FDA reports

2,516 females aged 60 (±5) who take the same drugs are studied. This is a personalized study for a 60 year old female patient who has Chronic Depression, Hypothyroidism, Nausea. The study is created by eHealthMe based on reports from FDA.

How to use this study: bring a copy to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Peer support for this study is available on our Ginger Health app. It's free, anonymous and secure. The app is ideal for people taking multiple medications or having multiple conditions.

On Feb, 10, 2019

2,516 females aged 60 (±5) who take Elavil, Synthroid, Xeljanz are studied.

Number of reports submitted per year:

Elavil, Synthroid, Xeljanz for a 60-year old woman.

Information of the patient in this study:

  • Age: 60
  • Gender: female
  • Conditions: Chronic Depression, Hypothyroidism, Nausea
  • Drugs taken:
    • Elavil (amitriptyline hydrochloride)
    • Synthroid (levothyroxine sodium)
    • Xeljanz (tofacitinib citrate)

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

  • Light-Headedness When Standing Up: 49 (1.95% of females aged 60 (±5) who take the drugs)
  • Shortness Of Breath: 44 (1.75% of females aged 60 (±5) who take the drugs)

As an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea

As an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea

Most common drug interactions over time

< 1 month:
  1. Diarrhea
  2. Cough
  3. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  4. Insomnia (sleeplessness)
  5. The flu (the flu is caused by an influenza virus)
  6. High blood pressure
  7. Drug ineffective
  8. Hyperhidrosis (abnormally increased sweating)
  9. Heart rate increased
  10. Nasopharyngitis (inflammation of the nasopharynx)
1 - 6 months:
  1. Fatigue (feeling of tiredness)
  2. Diarrhea
  3. Drug ineffective
  4. Joint pain
  5. Nasopharyngitis (inflammation of the nasopharynx)
  6. Rashes (redness)
  7. Pain in extremity
  8. Fungal infection
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Pain
6 - 12 months:
  1. Joint swelling
  2. Pain
  3. Headache (pain in head)
  4. Joint pain
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. The flu (the flu is caused by an influenza virus)
  7. Constipation
  8. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  9. Fall
  10. Weight increased
1 - 2 years:
  1. Cough
  2. High blood pressure
  3. Headache (pain in head)
  4. Nasopharyngitis (inflammation of the nasopharynx)
  5. Apnea (temporary absence or cessation of breathing)
  6. Drug ineffective
  7. Joint pain
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Pain
2 - 5 years:
  1. Acute kidney failure
  2. Stress and anxiety
  3. Drug hypersensitivity
  4. Disturbance in attention
  5. Memory loss
  6. Blood creatine phosphokinase increased
  7. Eye pain
  8. Weight decreased
  9. High blood cholesterol
  10. Joint pain
5 - 10 years:
  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Haemorrhagic anaemia (anaemia due to excessive bleeding)
  3. Chronic kidney disease
  4. Renal mass (mass in kidney)
  5. Hypotension (abnormally low blood pressure)
  6. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  7. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  8. Hair loss
  9. Dizziness
  10. Electrocardiogram t wave inversion
10+ years:
not specified:
  1. Pain
  2. Drug ineffective
  3. Joint pain
  4. Fatigue (feeling of tiredness)
  5. Weakness
  6. Headache (pain in head)
  7. Diarrhea
  8. Pain in extremity
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Breathing difficulty

Top conditions involved for these people *:

  1. Pain : 255 people, 10.14%
  2. High Blood Pressure : 199 people, 7.91%
  3. High Blood Cholesterol : 177 people, 7.03%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 129 people, 5.13%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 120 people, 4.77%
  6. Diabetes : 108 people, 4.29%
  7. Stress And Anxiety : 103 people, 4.09%
  8. Osteoporosis (bones weak and more likely to break): 85 people, 3.38%
  9. Insomnia (sleeplessness): 83 people, 3.30%
  10. Sleep Disorder : 80 people, 3.18%

Top co-used drugs for these people *:

  1. Lyrica (273 people, 10.85%)
  2. Enbrel (226 people, 8.98%)
  3. Celebrex (219 people, 8.70%)
  4. Nexium (217 people, 8.62%)
  5. Cymbalta (215 people, 8.55%)
  6. Premarin (201 people, 7.99%)
  7. Lasix (196 people, 7.79%)
  8. Humira (187 people, 7.43%)
  9. Methotrexate (187 people, 7.43%)
  10. Aspirin (187 people, 7.43%)

* Some reports may have incomplete information.

You are not alone:

What are the drugs?

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Related studies:

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FDA reports used in this study

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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