A study for a 54 year old woman who takes Humira, Lamictal - from FDA reports
222 females aged 54 (±5) who take the same drugs are studied. This is a personalized study for a 54 year old female patient who has Psoriatic Arthritis, Bipolar. The study is created by eHealthMe based on reports from FDA.
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222 females aged 54 (±5) who take Humira, Lamictal are studied.
Number of reports submitted per year:

Information of the patient in this study:
- Age: 54
- Gender: female
- Conditions: Psoriatic Arthritis, Bipolar
- Drugs taken:
- Humira (adalimumab)
- Lamictal (lamotrigine)
eHealthMe real world results:
Comparison with this patient's adverse outcomes:
- Bone And Joint Pain: 18 (8.11% of females aged 54 (±5) who take the drugs)
As an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea
- Bone And Joint Pain in Psoriatic Arthritis (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 (20% of females aged 54 (±5) who have Psoriatic Arthritis)
- Bone And Joint Pain in Bipolar (mood disorder): 139 (2.03% of females aged 54 (±5) who have Bipolar)
As an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea
- Bone And Joint Pain in Humira: 4,025 (7.44% of females aged 54 (±5) who take Humira)
- Bone And Joint Pain in Lamictal: 172 (3.26% of females aged 54 (±5) who take Lamictal)
Most common drug interactions over time
< 1 month:
- Injection site pain
- Drug ineffective
- Weight decreased
- Weakness
- Joint swelling
- Rashes (redness)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Dizziness
- Diabetes
1 - 6 months:
- Limb crushing injury (crushing injury of upper limb)
- Injection site pain
- Sinus disorder (disease of sinus)
- Psoriasis (immune-mediated disease that affects the skin)
- Pruritus generalised (generalized itching)
- Exostosis (formation of new bone on the surface of a bone)
- Herpes zoster
- Night sweats (sweating in night)
- Rashes (redness)
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus)
6 - 12 months:
- Weakness
- Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
- Cough
- Headache (pain in head)
- Joint pain
- Red blood cell sedimentation rate increased
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Acute kidney failure
- Cardiac failure
- Migraine (headache)
1 - 2 years:
- Procedural pain
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen)
- Abdominal pain
- Post procedural complication
- Limb injury
- Nasopharyngitis (inflammation of the nasopharynx)
- Confusional state
- Abscess limb (limb infection)
- Fever
- Joint pain
2 - 5 years:
- Nasopharyngitis (inflammation of the nasopharynx)
- Drug ineffective
- Nausea (feeling of having an urge to vomit)
- Cuts and puncture wounds
- Iron deficiency anaemia
- Bone pain
- Joint pain
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Weight decreased
- Surgery
5 - 10 years:
- Urinary tract infection
- Dizziness
- Dehydration (dryness resulting from the removal of water)
- Bacterial sepsis
- Pain
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
- Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
- Pancreatic cyst
- Weakness
10+ years:
n/anot specified:
- Injection site pain
- Drug ineffective
- Joint pain
- Diarrhea
- Fatigue (feeling of tiredness)
- Pain
- Headache (pain in head)
- Rashes (redness)
- Nausea (feeling of having an urge to vomit)
- Psoriasis (immune-mediated disease that affects the skin)
Top conditions involved for these people *:
- Depression : 80 people, 36.04%
- Stress And Anxiety : 54 people, 24.32%
- Pain : 47 people, 21.17%
- High Blood Pressure : 46 people, 20.72%
- Insomnia (sleeplessness): 41 people, 18.47%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 33 people, 14.86%
- High Blood Cholesterol : 32 people, 14.41%
- Psoriasis (immune-mediated disease that affects the skin): 28 people, 12.61%
- Vitamin Supplementation : 26 people, 11.71%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 21 people, 9.46%
Top co-used drugs for these people *:
- Methotrexate (44 people, 19.82%)
- Folic Acid (25 people, 11.26%)
- Abilify (24 people, 10.81%)
- Clonazepam (24 people, 10.81%)
- Klonopin (24 people, 10.81%)
- Vitamin D (22 people, 9.91%)
- Cymbalta (22 people, 9.91%)
- Seroquel (21 people, 9.46%)
- Omeprazole (20 people, 9.01%)
- Synthroid (19 people, 8.56%)
* Some reports may have incomplete information.
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What are the drugs?
- Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. (latest outcomes from Humira 454,471 users)
- Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. (latest outcomes from Lamictal 64,115 users)
What are the conditions?
- Psoriatic arthritis (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop) can be treated by Methotrexate, Humira, Enbrel, Methotrexate sodium, Sulfasalazine (latest reports from 1,008 Psoriatic arthritis patients)
- Bipolar (mood disorder) can be treated by Lamictal, Lithium carbonate, Seroquel, Depakote, Abilify (latest reports from 78,099 Bipolar patients)
What are the symtoms?
- Bone and joint pain has been reported by people with rheumatoid arthritis, osteoporosis, high blood cholesterol, high blood pressure, psoriatic arthropathy (latest reports from 279,970 Bone and joint pain patients).
Could your drugs cause:
Could your conditions cause:
Related studies:
- Humira and Lamictal drug interaction (803 reports)
Related publications that referenced our studies
- Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
- Malisiewicz B, Murer C, Schmid JP, French LE, Schmid-Grendelmeier P, Navarini AA, "Eosinophilia during psoriasis treatment with TNF antagonists", Dermatology, 2015 Jan .
- Gupta MC, Khanna J, Mathur R, Mittal N, "Lamotrigine-induced fulminant hepatic failure: an unusual presentation", IMSEAR, 2015 Jan .
- Alonso-Navarro H, Montes JM, Plaza-Nieto JF, Jiménez-Jiménez FJ, "Cataplexy Possibly Associated With Lamotrigine", Journal of clinical psychopharmacology, 2016 Aug .
- Ayano G, "Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics and Therapeutic Effects and Indications of Valproate: Review of Articles", Bipolar Disord, 2014 Jan .
FDA reports used in this study
- Want to find out more about the FDA reports used in the study? You can request them from FDA.
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