A study for a 53 year old woman who takes Methotrexate, Hydroxychloroquine Sulfate, Levothyroxine Thyroid, Folic Acid - from FDA reports


2,246 females aged 53 (±5) who take the same drugs are studied. This is a personalized study for a 53 year old female patient who has Under Active Thyroids, Rheumatoid Arthritis. The study is created by eHealthMe based on reports from FDA.

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On Feb, 16, 2019

2,246 females aged 53 (±5) who take Methotrexate, Hydroxychloroquine Sulfate, Levothyroxine Thyroid, Folic Acid are studied.


Number of reports submitted per year:

Methotrexate, Hydroxychloroquine Sulfate, Levothyroxine Thyroid, Folic Acid for a 53-year old woman.

Information of the patient in this study:

  • Age: 53
  • Gender: female
  • Conditions: Under Active Thyroids, Rheumatoid Arthritis
  • Drugs taken:
    • Methotrexate (methotrexate sodium)
    • Levothyroxine Thyroid (levothyroxine sodium)
    • Hydroxychloroquine Sulfate (hydroxychloroquine sulfate)
    • Folic Acid (folic acid)

eHealthMe real world results:

Most common drug interactions over time

< 1 month:
  1. Headache (pain in head)
  2. Gallbladder disorder
  3. Cervix carcinoma stage ii (cancer has spread beyond the cervix but not to the pelvic wall)
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Chest pain
  6. Nail infection
  7. Gastroenteritis (inflammation of stomach and intestine)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Effusion (an escape of fluid into a body cavity)
  10. Breast pain
1 - 6 months:
  1. Pneumonia
  2. Pain
  3. Impaired healing
  4. Cyst (a closed sac)
  5. Drug ineffective
  6. Mycobacterium avium complex infection
  7. Skin ulcer
  8. Joint pain
  9. Pain in extremity
  10. Lung adenocarcinoma (a form of non-small cell lung cancer)
6 - 12 months:
  1. Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
  2. Skin cancer
  3. Mouth ulcers
  4. Drug ineffective
  5. Arteriovenous fistula site haemorrhage
  6. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  7. Squamous cell carcinoma (a cancer of a kind of epithelial cell)
  8. Cervix carcinoma stage ii (cancer has spread beyond the cervix but not to the pelvic wall)
  9. Disease progression
  10. Gastric dilatation (a twisted stomach)
1 - 2 years:
  1. Drug ineffective
  2. Lung adenocarcinoma (a form of non-small cell lung cancer)
  3. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  4. Hair loss
  5. Stress and anxiety
  6. Fractured sacrum
  7. Jaw fracture
  8. Depression
  9. Joint pain
  10. Oedema peripheral (superficial swelling)
2 - 5 years:
  1. Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
  2. Fatigue (feeling of tiredness)
  3. Drug ineffective
  4. Joint pain
  5. Drug intolerance (drug sensitivity)
  6. Visual impairment
  7. Drowsiness
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Joint swelling
  10. Gait disturbance
5 - 10 years:
  1. Endometrial cancer recurrent
  2. Migraine (headache)
  3. Allergic rhinitis
  4. Hypersensitivity
  5. Swelling
  6. Endometrial cancer
  7. Haemorrhage (bleeding)
  8. Abdominal pain upper
  9. Asthma
  10. Stress and anxiety
10+ years:
  1. High blood pressure
  2. Fall
  3. Accident at work
  4. Joint pain
  5. Hand fracture
  6. Accident
  7. Pain
  8. Arthropathy
  9. Multiple fractures
  10. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
not specified:
  1. Drug ineffective
  2. Joint pain
  3. Fatigue (feeling of tiredness)
  4. Pain
  5. Injection site pain
  6. Nausea (feeling of having an urge to vomit)
  7. Headache (pain in head)
  8. Pain in extremity
  9. Joint swelling
  10. Sinusitis (inflammation of sinus)

Top conditions involved for these people *:

  1. High Blood Pressure : 211 people, 9.39%
  2. Pain : 195 people, 8.68%
  3. Vitamin Supplementation : 160 people, 7.12%
  4. Depression : 149 people, 6.63%
  5. High Blood Cholesterol : 117 people, 5.21%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 108 people, 4.81%
  7. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 103 people, 4.59%
  8. Preventive Health Care : 77 people, 3.43%
  9. Stress And Anxiety : 71 people, 3.16%
  10. Insomnia (sleeplessness): 64 people, 2.85%

Top co-used drugs for these people *:

  1. Humira (777 people, 34.59%)
  2. Enbrel (688 people, 30.63%)
  3. Prednisone (580 people, 25.82%)
  4. Omeprazole (210 people, 9.35%)
  5. Cymbalta (175 people, 7.79%)
  6. Remicade (170 people, 7.57%)
  7. Celebrex (160 people, 7.12%)
  8. Arava (146 people, 6.50%)
  9. Aspirin (134 people, 5.97%)
  10. Lisinopril (132 people, 5.88%)

* Some reports may have incomplete information.

You are not alone:

What are the drugs?

What are the conditions?



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FDA reports used in this study


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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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