A study for a 61 year old woman who takes Prolia, Levothroid - from FDA reports


706 females aged 61 (±5) who take the same drugs are studied. This is a personalized study for a 61 year old female patient who has Osteoporosis, Hypothyroidism. The study is created by eHealthMe based on reports from FDA.

How to use this study: bring a copy to your health teams to ensure drug risks and benefits are fully discussed and understood.


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On Feb, 21, 2019

706 females aged 61 (±5) who take Prolia, Levothroid are studied.


Number of reports submitted per year:

Prolia, Levothroid for a 61-year old woman.

Information of the patient in this study:

  • Age: 61
  • Gender: female
  • Conditions: Osteoporosis, Hypothyroidism
  • Drugs taken:
    • Prolia (denosumab)
    • Levothroid (levothyroxine sodium)

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

  • Migraines: 0 (0% of females aged 61 (±5) who take the drugs)

As an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea

As an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea

Most common drug interactions over time

< 1 month:
  1. Joint pain
  2. Weakness
  3. Nausea and vomiting
  4. Osteonecrosis of jaw (death of bone of jaw)
  5. Osteomyelitis (infection of bone)
  6. Pain in extremity
  7. Pain
  8. Toothaches (tooth pain)
  9. Headache (pain in head)
  10. Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back))
1 - 6 months:
  1. Urticaria (rash of round, red welts on the skin that itch intensely)
  2. Pain in extremity
  3. Skin exfoliation (removal of the oldest dead skin cells)
  4. Nerve compression
  5. Pain in jaw
  6. Fatigue (feeling of tiredness)
  7. Chest pain
  8. Skin blushing/flushing (a sudden reddening of the face, neck)
  9. Tooth resorption (the breakdown or destruction, and subsequent loss, of the root structure of a tooth)
  10. Skin disorder (skin disease)
6 - 12 months:
  1. Pain
  2. Osteonecrosis of jaw (death of bone of jaw)
  3. Breast cancer recurrent
  4. Breathing difficulty
  5. Pain in extremity
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  7. Gait disturbance
  8. Muscle spasms (muscle contraction)
  9. Hypotension (abnormally low blood pressure)
  10. Malaise (a feeling of general discomfort or uneasiness)
1 - 2 years:
  1. Adverse drug reaction
  2. Tooth loss
  3. Urinary tract infection
  4. Pain in jaw
  5. Fever
  6. Drug ineffective
  7. Gingival pain (gum pain)
  8. Oropharyngeal pain
  9. Rib fracture
  10. Lung infection
2 - 5 years:
  1. Atypical femur fracture
  2. Joint pain
  3. Pain in jaw
  4. Rashes (redness)
  5. Trismus (reduced opening of the jaws)
  6. Neck pain
  7. Meniere's disease (a disorder of the inner ear that can affect hearing and balance to a varying degree)
  8. Sjogren syndrome (a disease that causes dryness in the mouth and eyes)
  9. Butterfly rash
  10. Back pain
5 - 10 years:
n/a
10+ years:
n/a
not specified:
  1. Joint pain
  2. Nausea (feeling of having an urge to vomit)
  3. Pain in extremity
  4. Back pain
  5. Pain
  6. Fatigue (feeling of tiredness)
  7. Rashes (redness)
  8. Diarrhea
  9. Weakness
  10. Breathing difficulty

Top conditions involved for these people *:

  1. Pain : 42 people, 5.95%
  2. Breast Cancer : 35 people, 4.96%
  3. High Blood Pressure : 32 people, 4.53%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 31 people, 4.39%
  5. Preventive Health Care : 26 people, 3.68%
  6. Osteopenia (a condition where bone mineral density is lower than normal): 24 people, 3.40%
  7. Metastases To Bone (cancer spreads to bone): 24 people, 3.40%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 24 people, 3.40%
  9. Breast Cancer Metastatic : 22 people, 3.12%
  10. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 21 people, 2.97%

Top co-used drugs for these people *:

  1. Calcium (140 people, 19.83%)
  2. Vitamin D (114 people, 16.15%)
  3. Vitamin D3 (67 people, 9.49%)
  4. Fish Oil (44 people, 6.23%)
  5. Lipitor (42 people, 5.95%)
  6. Cymbalta (41 people, 5.81%)
  7. Nexium (38 people, 5.38%)
  8. Vitamin B12 (36 people, 5.10%)
  9. Ibrance (32 people, 4.53%)
  10. Singulair (32 people, 4.53%)

* Some reports may have incomplete information.

You are not alone:

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What are the symtoms?

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Related studies:

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FDA reports used in this study


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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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