A study for a 75 year old woman who takes Synthroid, Estradiol - from FDA reports


739 females aged 75 (±5) who take the same drugs are studied. This is a personalized study for a 75 year old female patient who has Low Thyroid, Postmenopausal Symptoms. The study is created by eHealthMe based on reports from FDA.

How the study uses the data?

The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered.

What are the drugs?

What are the conditions?

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.

On Mar, 13, 2019

739 females aged 75 (±5) who take Synthroid, Estradiol are studied.

Number of reports submitted per year:

Synthroid, Estradiol for a 75-year old woman.

Information of the patient in this study:

  • Age: 75
  • Gender: female
  • Conditions: Low Thyroid, Postmenopausal Symptoms
  • Drugs taken:
    • Synthroid (levothyroxine sodium)
    • Estradiol (estradiol)

eHealthMe real world results:

Most common drug interactions over time

< 1 month:
  1. Headache (pain in head)
  2. Breast pain
  3. Heart palpitations (feelings or sensations that your heart is pounding or racing)
  4. Hypersensitivity
  5. Rash papular (redness with papule)
  6. Urination - painful
  7. High blood pressure
  8. Pelvic pain
  9. Gastric disorder (disease of stomach)
  10. Abdominal pain lower
1 - 6 months:
  1. Cataract (clouding of the lens inside the eye)
  2. Itching
  3. Vascular compression
  4. Drowsiness
  5. Gait disturbance
  6. Blindness
  7. Hoarseness or changing voice
  8. Blood thyroid stimulating hormone increased
  9. Psychomotor hyperactivity (feelings of extreme restlessness)
  10. Blood oestrogen increased
6 - 12 months:
  1. Hypoaesthesia (reduced sense of touch or sensation)
  2. Breast cancer female
  3. Wound
  4. Impaired driving ability
  5. Head injury
  6. Gait disturbance
  7. Nerve injury
  8. Fall
  9. Balance disorder
  10. Dizziness
1 - 2 years:
  1. Loose stools
  2. Pulmonary embolism (blockage of the main artery of the lung)
  3. Nausea (feeling of having an urge to vomit)
  4. Diarrhea
  5. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
2 - 5 years:
  1. Breast cancer
  2. Breast cancer female
  3. Completed suicide (act of taking one's own life)
  4. Constipation
  5. Hair loss
  6. Thrombosis (formation of a blood clot inside a blood vessel)
  7. Joint pain
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Headache (pain in head)
  10. Migraine (headache)
5 - 10 years:
  1. Gouty arthritis (joint inflammation with crystal formation)
  2. Depression
  3. Peripheral vascular disorder
  4. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  5. Radiation therapy
  6. Acute myocardial infarction (acute heart attack)
  7. Angioplasty
  8. Endometrial disorder
  9. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  10. Cholecystitis (infection of gallbladder)
10+ years:
  1. Breast cancer female
  2. Urinary tract infection
  3. Gingival bleeding (bleeding gums)
  4. Cataract (clouding of the lens inside the eye)
  5. Lung cancer metastatic (lung cancer spreads to other parts)
not specified:
  1. Drug ineffective
  2. Joint pain
  3. Nausea (feeling of having an urge to vomit)
  4. Anaemia (lack of blood)
  5. Herpes zoster
  6. Headache (pain in head)
  7. Peripheral swelling
  8. Fatigue (feeling of tiredness)
  9. High blood cholesterol
  10. Fibromyalgia (a long-term condition which causes pain all over the body)

Top conditions involved for these people *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 80 people, 10.83%
  2. High Blood Pressure : 69 people, 9.34%
  3. High Blood Cholesterol : 60 people, 8.12%
  4. Osteoporosis (bones weak and more likely to break): 44 people, 5.95%
  5. Pain : 42 people, 5.68%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 40 people, 5.41%
  7. Vulvovaginal Dryness : 37 people, 5.01%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 30 people, 4.06%
  9. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 28 people, 3.79%
  10. Multiple Myeloma (cancer of the plasma cells): 28 people, 3.79%

Top co-used drugs for these people *:

  1. Lasix (98 people, 13.26%)
  2. Lipitor (70 people, 9.47%)
  3. Humira (66 people, 8.93%)
  4. Ativan (65 people, 8.80%)
  5. Vitamin D (55 people, 7.44%)
  6. Dilaudid (54 people, 7.31%)
  7. Remicade (51 people, 6.90%)
  8. Fosamax (48 people, 6.50%)
  9. Aspirin (47 people, 6.36%)
  10. Arava (47 people, 6.36%)

* Some reports may have incomplete information.

What is next?

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FDA reports used in this study

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