A study for a 53 year old man who takes Amlodipine, Spironolactone, Lisinopril - from FDA reports


3,296 males aged 53 (±5) who take the same drugs are studied. This is a personalized study for a 53 year old male patient who has High Blood Pressure. The study is created by eHealthMe based on reports from FDA.

How the study uses the data?

The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered.

What are the drugs?

What are the conditions?

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.

On Mar, 14, 2019

3,296 males aged 53 (±5) who take Amlodipine, Spironolactone, Lisinopril are studied.

Number of reports submitted per year:

Amlodipine, Spironolactone, Lisinopril for a 53-year old man.

Information of the patient in this study:

  • Age: 53
  • Gender: male
  • Conditions: High Blood Pressure
  • Drugs taken:
    • Amlodipine (amlodipine besylate)
    • Spironolactone (spironolactone)
    • Lisinopril (lisinopril)

eHealthMe real world results:

Most common drug interactions over time

< 1 month:
  1. Hallucinations (sensations that appear real but are created by your mind)
  2. Diarrhea
  3. Haemoglobin increased
  4. Heart attack
  5. White blood cell count increased
  6. Liver carcinoma ruptured (ruptured liver cancer tumour)
  7. Circulatory collapse
  8. Lymphocyte count decreased
  9. Hepatic failure (liver failure)
  10. Alanine aminotransferase increased
1 - 6 months:
  1. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen)
  2. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  3. Drug ineffective
  4. Heart attack
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Headache (pain in head)
  7. Pneumonia
  8. Renal impairment (severely reduced kidney function)
  9. Muscle aches (muscle pain)
  10. Swallowing difficulty
6 - 12 months:
  1. Cerebral haemorrhage (bleeding within the brain)
  2. Varices oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach)
  3. Death
  4. Hypotension (abnormally low blood pressure)
  5. Dehydration (dryness resulting from the removal of water)
  6. Haematoma (collection of blood outside the blood vessels)
  7. Haematemesis (vomiting of blood)
  8. Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
  9. Rectal haemorrhage (bleeding from anus)
  10. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen)
1 - 2 years:
  1. Lip swelling
  2. Epiglottitis (inflammation of the epiglottis)
  3. Angioedema (rapid swelling of the dermis)
  4. Renal impairment (severely reduced kidney function)
  5. Injury
  6. Breathing sounds - abnormal (stridor)
  7. Pancreatitis (inflammation of pancreas)
  8. Pain
  9. Weight decreased
  10. Death
2 - 5 years:
  1. Acute kidney failure
  2. Blood alkaline phosphatase increased
  3. Urinary tract infection
  4. Alanine aminotransferase increased
  5. Gamma-glutamyltransferase increased
  6. Constipation
  7. Hyperkalemia (damage to or disease of the kidney)
  8. Aspartate aminotransferase increased
  9. Renal failure acute (rapid kidney dysfunction)
  10. Stress and anxiety
5 - 10 years:
  1. Acute kidney failure
  2. Emotional distress
  3. Stress and anxiety
  4. Depression
  5. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen)
  6. Pain
  7. Diabetes
  8. Injury
  9. Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
  10. Glaucoma (increased fluid pressure in the eye with vision loss)
10+ years:
  1. Speech impairment (adult) (inability to speak (adult))
  2. Anaemia (lack of blood)
  3. Muscle spasms (muscle contraction)
  4. Cardiac failure acute
  5. Blood urine present
  6. Confusional state
  7. Coronary heart disease (narrowing or blockage of the coronary arteries)
  8. Cardiac failure congestive
  9. Weakness
  10. Breathing difficulty
not specified:
  1. Fatigue (feeling of tiredness)
  2. Nausea (feeling of having an urge to vomit)
  3. Breathing difficulty
  4. Weakness
  5. Hypotension (abnormally low blood pressure)
  6. Pain
  7. Cardiac failure congestive
  8. Diarrhea
  9. Heart attack
  10. Dizziness

Top conditions involved for these people *:

  1. Diabetes : 312 people, 9.47%
  2. High Blood Cholesterol : 296 people, 8.98%
  3. Pain : 240 people, 7.28%
  4. Type 2 Diabetes : 149 people, 4.52%
  5. Depression : 141 people, 4.28%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 136 people, 4.13%
  7. Hepatitis C : 116 people, 3.52%
  8. Stress And Anxiety : 97 people, 2.94%
  9. Cardiac Disorder : 95 people, 2.88%
  10. Preventive Health Care : 94 people, 2.85%

Top co-used drugs for these people *:

  1. Lasix (480 people, 14.56%)
  2. Aspirin (335 people, 10.16%)
  3. Lipitor (327 people, 9.92%)
  4. Metformin (323 people, 9.80%)
  5. Plavix (273 people, 8.28%)
  6. Coreg (249 people, 7.55%)
  7. Furosemide (249 people, 7.55%)
  8. Lantus (217 people, 6.58%)
  9. Hydrochlorothiazide (211 people, 6.40%)
  10. Simvastatin (190 people, 5.76%)

* Some reports may have incomplete information.

What is next?

You are not alone:

Related publications that referenced our studies

Related studies:

FDA reports used in this study

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