A study for a 65 year old man who takes Amlodipine, Sertraline Hydrochloride, Lisinopril - from FDA reports


4,758 males aged 65 (±5) who take the same drugs are studied. This is a personalized study for a 65 year old male patient who has High Blood Pressure, Panic Attacks, High Blood Sugar. The study is created by eHealthMe based on reports from FDA.

How the study uses the data?

The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered.

What are the drugs?

What are the conditions?

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.

On Mar, 15, 2019

4,758 males aged 65 (±5) who take Amlodipine, Sertraline Hydrochloride, Lisinopril are studied.

Number of reports submitted per year:

Amlodipine, Sertraline Hydrochloride, Lisinopril for a 65-year old man.

Information of the patient in this study:

  • Age: 65
  • Gender: male
  • Conditions: High Blood Pressure, Panic Attacks, High Blood Sugar
  • Drugs taken:
    • Amlodipine (amlodipine besylate)
    • Sertraline Hydrochloride (sertraline hydrochloride)
    • Lisinopril (lisinopril)

eHealthMe real world results:

Most common drug interactions over time

< 1 month:
  1. Hypotension (abnormally low blood pressure)
  2. Dehydration (dryness resulting from the removal of water)
  3. Skin ulcer
  4. Oedema peripheral (superficial swelling)
  5. Cough
  6. Diarrhea
  7. Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
  8. Chest pain
  9. Angioedema (rapid swelling of the dermis)
  10. Hypersensitivity
1 - 6 months:
  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Pneumonia
  3. Hyperkalemia (damage to or disease of the kidney)
  4. Cardiac arrest
  5. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  6. Septic shock (shock due to blood infection)
  7. Low tissue oxygen
  8. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration)
  9. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  10. Breathing difficulty
6 - 12 months:
  1. Diarrhea
  2. Skin ulcer
  3. Pericardial effusion (fluid around the heart)
  4. Hair loss
  5. Hypotension (abnormally low blood pressure)
  6. Weakness
  7. Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus)
  8. High blood cholesterol
  9. Fatigue (feeling of tiredness)
  10. Dry skin
1 - 2 years:
  1. Interstitial nephritis (inflammation of the kidney)
  2. Anaemia (lack of blood)
  3. Chronic kidney disease
  4. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen)
  5. Renal impairment (severely reduced kidney function)
  6. Injury
  7. Glomerular filtration rate abnormal
  8. Pain
  9. Scar
  10. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
2 - 5 years:
  1. Chronic kidney disease
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Angioedema (rapid swelling of the dermis)
  4. Acute kidney failure
  5. Hyperkalemia (damage to or disease of the kidney)
  6. Anaemia (lack of blood)
  7. Abdominal pain upper
  8. Renal impairment (severely reduced kidney function)
  9. Presyncope
  10. Cerebral haemorrhage (bleeding within the brain)
5 - 10 years:
  1. Chronic kidney disease
  2. Acute kidney failure
  3. Subdural haematoma (blood collects between the skull and the surface of the brain)
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Cerebral haemorrhage (bleeding within the brain)
  6. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  7. Fall
  8. Diverticulum intestinal haemorrhagic (a pouch that is attached to the first part of the small intestine with bleeding)
  9. Coughing up blood
  10. Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
10+ years:
  1. Renal failure acute (rapid kidney dysfunction)
  2. Breathing difficulty
  3. Dehydration (dryness resulting from the removal of water)
  4. Neck pain
  5. Fatigue (feeling of tiredness)
  6. Back pain
  7. Blood creatinine increased
  8. Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
  9. Blood urea increased
  10. Fluid overload (too much fluid in the blood)
not specified:
  1. Fatigue (feeling of tiredness)
  2. Breathing difficulty
  3. Pain
  4. Weakness
  5. Nausea (feeling of having an urge to vomit)
  6. Diarrhea
  7. Dizziness
  8. Drug ineffective
  9. Pneumonia
  10. Hypotension (abnormally low blood pressure)

Top conditions involved for these people *:

  1. Diabetes : 426 people, 8.95%
  2. High Blood Cholesterol : 419 people, 8.81%
  3. Pain : 378 people, 7.94%
  4. Type 2 Diabetes : 286 people, 6.01%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 286 people, 6.01%
  6. Multiple Myeloma (cancer of the plasma cells): 248 people, 5.21%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 225 people, 4.73%
  8. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 174 people, 3.66%
  9. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 154 people, 3.24%
  10. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 139 people, 2.92%

Top co-used drugs for these people *:

  1. Metformin (559 people, 11.75%)
  2. Aspirin (529 people, 11.12%)
  3. Lipitor (477 people, 10.03%)
  4. Plavix (431 people, 9.06%)
  5. Lasix (366 people, 7.69%)
  6. Simvastatin (304 people, 6.39%)
  7. Lantus (288 people, 6.05%)
  8. Nexium (277 people, 5.82%)
  9. Hydrochlorothiazide (266 people, 5.59%)
  10. Atenolol (255 people, 5.36%)

* Some reports may have incomplete information.

What is next?

You are not alone:

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FDA reports used in this study

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