Accutane side effects - from FDA reports


In this review, we analyze Accutane side effects by the time on the drug, gender and age of the people who have side effects while taking Accutane. The review is based on 30,956 people who have side effects while taking the drug from FDA, and is updated regularly.

How to use this study: bring a copy to your health teams to ensure drug risks and benefits are fully discussed and understood.


Peer to Peer mobile support

Peer support for this study is available on our Ginger Health app. It's free, anonymous and secure. The app is ideal for people taking multiple medications or having multiple conditions.


Accutane

Accutane has active ingredients of isotretinoin. It is often used in acne. (latest outcomes from Accutane 32,192 users)


On Feb, 22, 2019

30,956 people who take Accutane are studied.


Number of reports submitted per year:

Accutane side effects.

Most common side effects over time *:

< 1 month:
  • Pregnancy
  • Suicidal ideation
  • Weight decreased
  • Inflammatory bowel disease
  • Weight increased
  • Anxiety
  • Vision blurred
  • White blood cell count increased
  • Xerosis (abnormal dryness of the skin or mucus membranes)
  • Injury
1 - 6 months:
  • Rectal haemorrhage (bleeding from anus)
  • Depression
  • Weight increased
  • Stress
  • Small intestinal obstruction (blockage in small intestine)
  • Lip dry
  • Anxiety
  • Xerosis (abnormal dryness of the skin or mucus membranes)
  • Gastrointestinal injury (injury to gastrointestinal tract)
  • Vomiting
6 - 12 months:
  • Inflammatory bowel disease
  • Suicidal ideation
  • Injury
  • Gastrointestinal injury (injury to gastrointestinal tract)
  • Pregnancy
  • Irritable bowel syndrome
  • Rectal haemorrhage (bleeding from anus)
  • Colitis ulcerative (inflammation of colon with ulcer)
  • Weight decreased
  • Depression
1 - 2 years:
  • Inflammatory bowel disease
  • Gastrointestinal injury (injury to gastrointestinal tract)
  • Injury
  • Irritable bowel syndrome
  • Colitis ulcerative (inflammation of colon with ulcer)
  • Suicidal ideation
  • Intestinal obstruction
  • Rectal haemorrhage (bleeding from anus)
  • Depression
  • Crohn's disease (condition that causes inflammation of the gastrointestinal tract)
2 - 5 years:
  • Injury
  • Inflammatory bowel disease
  • Irritable bowel syndrome
  • Gastrointestinal injury (injury to gastrointestinal tract)
  • Colitis ulcerative (inflammation of colon with ulcer)
  • Crohn's disease (condition that causes inflammation of the gastrointestinal tract)
  • Depression
  • Intestinal obstruction
  • Suicidal ideation
  • Rectal haemorrhage (bleeding from anus)
5 - 10 years:
  • Inflammatory bowel disease
  • Irritable bowel syndrome
  • Injury
  • Rectal haemorrhage (bleeding from anus)
  • Suicidal ideation
  • Depression
  • Gastrointestinal injury (injury to gastrointestinal tract)
  • Weight decreased
  • Colitis ulcerative (inflammation of colon with ulcer)
  • Anxiety
10+ years:
  • Pregnancy
  • Inflammatory bowel disease
  • Weight increased
  • Anxiety
  • Blood cholesterol increased
  • Crohn's disease (condition that causes inflammation of the gastrointestinal tract)
  • Depression
  • Emotional distress
  • Stress
  • Suicide attempt
not specified:
  • Suicidal ideation
  • Pregnancy
  • Weight decreased
  • Inflammatory bowel disease
  • Injury
  • Rectal haemorrhage (bleeding from anus)
  • Suicide attempt
  • Irritable bowel syndrome
  • Vision blurred
  • Weight increased

Most common side effects by gender *:

female:
  • Suicidal ideation
  • Inflammatory bowel disease
  • Injury
  • Weight decreased
  • Irritable bowel syndrome
  • Pregnancy
  • Weight increased
  • Colitis ulcerative (inflammation of colon with ulcer)
  • Depression
  • Gastrointestinal injury (injury to gastrointestinal tract)
male:
  • Inflammatory bowel disease
  • Suicidal ideation
  • Lip dry
  • Suicide attempt
  • Anxiety
  • Small intestinal obstruction (blockage in small intestine)
  • Vomiting
  • Intestinal obstruction
  • Stress
  • Weight increased

Most common side effects by age *:

0-1:
  • Growth retardation (delayed growth)
  • Maternal drugs affecting foetus (chemical affecting the baby before birth taken by mother)
  • Placenta praevia (condition that occurs during pregnancy when the placenta is abnormally placed, and partially or totally covers the cervix)
  • Premature separation of placenta
  • Small for dates baby (an unborn baby is growing more slowly and is smaller than most babies are at the same age)
  • Tachypnoea (condition of rapid breathing over 20 per minute)
  • Vaginal haemorrhage (vaginal bleeding)
  • White blood cells urine positive
  • Facial dysmorphism (an anatomical malformation of face)
  • Feeling abnormal
2-9:
  • Injury
  • Neuroblastoma (a cancer that forms in your nerve tissue)
  • Suicidal ideation
  • Arthropathy
  • Erythema (redness of the skin)
  • Intestinal obstruction
  • Irritable bowel syndrome
  • Polyp
  • Rash
  • Suicide attempt
10-19:
  • Weight decreased
  • Suicidal ideation
  • Inflammatory bowel disease
  • Suicide attempt
  • Depression
  • Colitis ulcerative (inflammation of colon with ulcer)
  • Rectal haemorrhage (bleeding from anus)
  • Lip dry
  • Weight increased
  • Irritable bowel syndrome
20-29:
  • Anaemia (lack of blood)
  • Alopecia (absence of hair from areas of the body)
  • Lip dry
  • Visual disturbance
  • Anxiety
  • Stress
  • Intestinal obstruction
  • Abdominal pain
  • Weight decreased
  • Suicidal ideation
30-39:
  • Suicidal ideation
  • Inflammatory bowel disease
  • Weight decreased
  • Colitis ulcerative (inflammation of colon with ulcer)
  • Irritable bowel syndrome
  • Weight increased
  • Depression
  • Vision blurred
  • Suicide attempt
  • Rectal haemorrhage (bleeding from anus)
40-49:
  • Suicidal ideation
  • Irritable bowel syndrome
  • Inflammatory bowel disease
  • Small intestinal obstruction (blockage in small intestine)
  • Weight decreased
  • Vision blurred
  • Suicide attempt
  • Depression
  • Stress
  • Colitis ulcerative (inflammation of colon with ulcer)
50-59:
  • Irritable bowel syndrome
  • Suicidal ideation
  • Injury
  • Stress
  • Inflammatory bowel disease
  • Rectal haemorrhage (bleeding from anus)
  • Vision blurred
  • Lip dry
  • Weight increased
  • Colitis ulcerative (inflammation of colon with ulcer)
60+:
  • Irritable bowel syndrome
  • Injury
  • Suicidal ideation
  • Stress
  • Small intestinal obstruction (blockage in small intestine)
  • Lip dry
  • Intestinal obstruction
  • Inflammatory bowel disease
  • Rectal haemorrhage (bleeding from anus)
  • Xerosis (abnormal dryness of the skin or mucus membranes)

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

You are not alone:

Related studies

All Accutane side effects from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Accutane (isotretinoin) is often used to treat acne. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

Related publications that referenced our studies


Recent updates

Recent general studies
Recent personal studies

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Submit your testimonial

  • Please fill in your Testimonial.
  • Please enter a minimum of 10 characters for your Testimonial.
  • Please fill in your Name.

Please wait...

{progressItem}

Thank you!