Acthar gel side effects by duration, gender and age - a phase IV clinical study of FDA data

Summary:

Side effects are reported by people who take Acthar gel. Common side effects include abasia among females and dyspnoea among males.

The phase IV clinical study is created by eHealthMe based on 73 reports from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.



On Jun, 16, 2022

73 people who take Acthar Gel and have side effects are studied.


What is Acthar Gel?

Acthar gel has active ingredients of corticotropin. eHealthMe is studying from 81 Acthar gel users for its effectiveness, alternative drugs and more.

Number of Acthar gel reports submitted per year:

Acthar gel side effects.

Acthar Gel side effects by time on the drug*:

< 1 month:

  1. Abdominal pain
  2. Aortic valve incompetence
  3. Blood glucose increased
  4. Blood potassium decreased
  5. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  6. Dysarthria (speech disorder)
  7. Injection site pain
  8. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  9. Sudden death
  10. Tremor (trembling or shaking movements in one or more parts of your body)

1 - 6 months:

  1. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  2. Renal failure acute (rapid kidney dysfunction)
  3. Sensation of heaviness
  4. Dyspnoea (difficult or laboured respiration)
  5. Asthenia (weakness)
  6. Blood chloride decreased
  7. Drug ineffective
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

6 - 12 months:

  1. Anxiety
  2. Arthralgia (joint pain)
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Insomnia (sleeplessness)
  5. Leukocytosis (increased white blood cells)

1 - 2 years:

n/a

2 - 5 years:

n/a

5 - 10 years:

n/a

10+ years:

n/a

not specified:

  1. Dyspnoea (difficult or laboured respiration)
  2. Abasia (inability to walk)
  3. Abdominal distension
  4. Blood pressure increased
  5. Drug ineffective
  6. Hypertension (high blood pressure)
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Abdominal pain
  9. Abdominal wall haemorrhage (bleeding from injured abdominal organs)
  10. Acute myocardial infarction (acute heart attack)

Acthar Gel side effects by gender *:

female:

  1. Abasia (inability to walk)
  2. Abdominal distension
  3. Abdominal pain
  4. Arthralgia (joint pain)
  5. Blood pressure increased
  6. Drug ineffective
  7. Hypertension (high blood pressure)
  8. Acute respiratory failure
  9. Adenocarcinoma pancreas (cancer of pancreas)
  10. Adrenal insufficiency (condition in which the adrenal glands do not produce adequate amounts of steroids)

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Abdominal wall haemorrhage (bleeding from injured abdominal organs)
  3. Cushing's syndrome (obesity, a rounded face, increased fat)
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Drug ineffective
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. Headache (pain in head)
  8. Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
  9. Proteinuria (presence of protein in the urine)
  10. Renal failure acute (rapid kidney dysfunction)

Acthar Gel side effects by age (0-1 to 60+) *:

0-1:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Drug ineffective
  3. Dyspnoea (difficult or laboured respiration)
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Hypertension (high blood pressure)
  6. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

2-9:

  1. Abdominal distension
  2. Arrhythmia (irregular heartbeat)
  3. Cushing's syndrome (obesity, a rounded face, increased fat)
  4. Leukaemia (blood or bone marrow cancer)

10-19:

  1. Blood pressure increased

20-29:

  1. Abdominal pain
  2. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)

30-39:

  1. Dyspnoea (difficult or laboured respiration)
  2. Hypertension (high blood pressure)
  3. Proteinuria (presence of protein in the urine)

40-49:

  1. Abasia (inability to walk)
  2. Anxiety
  3. Abdominal pain
  4. Asthenia (weakness)
  5. Blood glucose increased
  6. Burning sensation
  7. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  8. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  9. Drug ineffective
  10. Erythema (redness of the skin)

50-59:

  1. Acute respiratory distress syndrome
  2. Acute respiratory failure
  3. Adrenal insufficiency (condition in which the adrenal glands do not produce adequate amounts of steroids)
  4. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  5. Aortic valve incompetence
  6. Arthralgia (joint pain)
  7. Cardiac failure
  8. Drug ineffective
  9. Dry eye (lack of adequate tears)
  10. Dysarthria (speech disorder)

60+:

  1. Arthralgia (joint pain)
  2. Asthenia (weakness)
  3. Blood chloride decreased
  4. Blood potassium decreased
  5. Blood pressure increased
  6. Headache (pain in head)
  7. Herpes virus infection
  8. Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
  9. Renal failure acute (rapid kidney dysfunction)
  10. Sudden death

* Approximation only. Some reports may have incomplete information.

Do you take Acthar gel?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



How the study uses the data?

The study is based on corticotropin (the active ingredients of Acthar gel) and Acthar gel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

Related studies

Alternative drugs to, pros and cons of Acthar gel:

All Acthar gel side effects from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

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