Acthar gel side effects by duration, gender and age - a phase IV clinical study of FDA data

< 1 month:

1. Abdominal pain
2. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
3. Altered state of consciousness (altered state of mind)
4. Aortic valve incompetence
5. Blood glucose increased
6. Blood potassium decreased
7. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
8. Drug hypersensitivity
9. Injection site pain

1 - 6 months:

1. Dehydration (dryness resulting from the removal of water)
2. Drug ineffective
3. Asthenia (weakness)
4. Dyspnoea (difficult or laboured respiration)
5. Acute abdomen
6. Blood chloride decreased
7. Cardiomyopathy (weakening of the heart muscle)

6 - 12 months:

1. Anxiety
2. Arthralgia (joint pain)
3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
4. Insomnia (sleeplessness)
5. Leukocytosis (increased white blood cells)

1 - 2 years:

n/a

2 - 5 years:

n/a

5 - 10 years:

n/a

10+ years:

n/a

not specified:

1. Abdominal distension
2. Dyspnoea (difficult or laboured respiration)
3. Abasia (inability to walk)
4. Blood pressure increased
5. Drug ineffective
6. Hypertension (high blood pressure)
7. Sepsis (a severe blood infection that can lead to organ failure and death)
8. Abdominal pain
9. Abdominal wall haemorrhage (bleeding from injured abdominal organs)
10. Acute myocardial infarction (acute heart attack)

female:

1. Abdominal distension
2. Abasia (inability to walk)
3. Abdominal pain
4. Arthralgia (joint pain)
5. Blood pressure increased
6. Drug hypersensitivity
7. Drug ineffective
8. Hypertension (high blood pressure)
9. Acute respiratory failure
10. Adenocarcinoma pancreas (cancer of pancreas)

male:

1. Dyspnoea (difficult or laboured respiration)
2. Asthenia (weakness)
3. Anxiety
4. Aortic valve incompetence
5. Blood glucose increased
6. Cardiac failure
7. Cardiac failure congestive
8. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
9. Dehydration (dryness resulting from the removal of water)
10. Drug ineffective

0-1:

1. Adrenal disorder
2. Cardiomyopathy (weakening of the heart muscle)
3. Dehydration (dryness resulting from the removal of water)
4. Drug ineffective
5. Dyspnoea (difficult or laboured respiration)
6. Hypertension (high blood pressure)

2-9:

1. Abdominal distension
2. Adrenomegaly (enlarged adrenal glands)
3. Arrhythmia (irregular heartbeat)
4. Leukaemia (blood or bone marrow cancer)

10-19:

1. Blood pressure increased

20-29:

1. Abdominal pain
2. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)

30-39:

1. Cardiac failure congestive
2. Dyspnoea (difficult or laboured respiration)
3. Hypertension (high blood pressure)

40-49:

1. Abasia (inability to walk)
2. Anxiety
3. Abdominal pain
4. Asthenia (weakness)
5. Blood glucose increased
6. Burning sensation
7. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
8. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
9. Drug hypersensitivity
10. Drug ineffective

50-59:

1. Abdominal distension
2. Acute respiratory distress syndrome
3. Acute respiratory failure
4. Adrenal insufficiency (condition in which the adrenal glands do not produce adequate amounts of steroids)
5. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
6. Aortic valve incompetence
7. Arthralgia (joint pain)
8. Asthenia (weakness)
9. Body temperature decreased
10. Cardiac failure

60+:

1. Acute myocardial infarction (acute heart attack)
2. Adenocarcinoma pancreas (cancer of pancreas)
3. Altered state of consciousness (altered state of mind)
4. Arthralgia (joint pain)
5. Asthenia (weakness)
6. Blood chloride decreased
7. Blood potassium decreased
8. Blood pressure increased
9. Headache (pain in head)
10. Herpes virus infection