Amlodipine besylate side effects by duration, gender and age - a phase IV clinical study of FDA data

Summary:

Side effects are reported by people who take Amlodipine besylate. Common side effects include death among females and death among males.

The phase IV clinical study is created by eHealthMe based on 44,682 reports from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On May, 21, 2022

44,682 people who take Amlodipine Besylate and have side effects are studied.

What is Amlodipine Besylate?

Amlodipine besylate has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 48,261 Amlodipine besylate users for its effectiveness, alternative drugs and more.

Number of Amlodipine besylate reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Amlodipine besylate?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

How the study uses the data?

The study is based on amlodipine besylate (the active ingredients of Amlodipine besylate) and Amlodipine besylate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

Related studies

Alternative drugs to, pros and cons of Amlodipine besylate:

Amlodipine besylate (48,261 reports)

Common Amlodipine besylate side effects:

Abasia (inability to walk): 125 reports
Abdominal discomfort: 535 reports
Abdominal distension: 366 reports
Abdominal pain: 546 reports
Abdominal pain upper: 613 reports
Acute kidney failure: 1,710 reports
Acute myocardial infarction (acute heart attack): 130 reports
Adverse drug reaction: 194 reports
Adverse event: 112 reports
Ageusia (loss of taste functions of the tongue): 118 reports
Agitation (state of anxiety or nervous excitement): 246 reports
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 300 reports
Alanine aminotransferase increased: 352 reports
Anaemia (lack of blood): 960 reports
Angioedema (rapid swelling of the dermis): 152 reports
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 162 reports
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 217 reports
Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 984 reports
Arrhythmias (irregular heartbeat): 369 reports
Arthritis (form of joint disorder that involves inflammation of one or more joints): 337 reports
Arthropathy: 176 reports
Ascites (accumulation of fluid in the abdominal cavity): 133 reports
Aspartate aminotransferase increased: 361 reports
Asthma: 254 reports
Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 528 reports
Back disorder: 110 reports
Back pain: 907 reports
Balance disorder: 342 reports
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 225 reports
Blood alkaline phosphatase increased: 208 reports
Blood bilirubin increased: 104 reports
Blood creatine phosphokinase increased: 217 reports
Blood creatinine increased: 498 reports
Blood glucose decreased: 149 reports
Blood glucose increased: 529 reports
Blood lactate dehydrogenase increased: 170 reports
Blood potassium decreased: 277 reports
Blood pressure fluctuation: 144 reports
Blood pressure management: 274 reports
Blood pressure systolic increased: 127 reports
Blood sodium decreased: 136 reports
Blood urea increased: 243 reports
Blood urine present: 106 reports
Body height decreased: 113 reports
Bone disorder: 109 reports
Bone pain: 249 reports
Bradycardia (abnormally slow heart action): 337 reports
Breathing difficulty: 1,776 reports
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 388 reports
Burning sensation: 229 reports
Cardiac arrest: 272 reports
Cardiac disorder: 301 reports
Cardiac failure: 326 reports
Cardiac failure congestive: 435 reports
Cardiogenic shock (inadequate circulation of blood): 102 reports
Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 176 reports
Cataract (clouding of the lens inside the eye): 330 reports
Cellulitis (infection under the skin): 223 reports
Cerebral haemorrhage (bleeding within the brain): 144 reports
Cerebral infarction (less blood supply to brain resulting tissue damage): 167 reports
Chest pain: 1,040 reports
Chills (felling of cold): 323 reports
Chronic kidney disease: 1,906 reports
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 230 reports
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 123 reports
Colitis (inflammation of colon): 109 reports
Completed suicide (act of taking one's own life): 494 reports
Condition: 696 reports
Confusion: 200 reports
Confusional state: 532 reports
Consciousness - decreased: 149 reports
Constipation: 1,127 reports
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 199 reports
Coronary heart disease (narrowing or blockage of the coronary arteries): 190 reports
Cough: 869 reports
Coughing up blood: 112 reports
C-reactive protein increased: 195 reports
Death: 1,352 reports
Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 199 reports
Dehydration (dryness resulting from the removal of water): 667 reports
Depressed level of consciousness: 276 reports
Depressed mood: 118 reports
Depression: 735 reports
Diabetes: 335 reports
Diarrhea: 2,337 reports
Discomfort: 101 reports
Disease progression: 264 reports
Disseminated intravascular coagulation (systemic activation of blood coagulation): 122 reports
Disturbance in attention: 116 reports
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 174 reports
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 123 reports
Dizziness: 1,974 reports
Drowsiness: 685 reports
Drug effect decreased: 223 reports
Drug eruption (adverse drug reaction of the skin): 102 reports
Drug hypersensitivity: 361 reports
Drug ineffective: 1,967 reports
Drug intolerance (drug sensitivity): 176 reports
Dry eyes (lack of adequate tears): 114 reports
Dry mouth: 347 reports
Dry skin: 328 reports
Dyskinesia (abnormality or impairment of voluntary movement): 110 reports
Dyspnea exertional: 183 reports
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 125 reports
Electrocardiogram qt prolonged: 106 reports
Emotional distress: 273 reports
Enlarged heart: 123 reports
Erythema multiforme (a type of hypersensitivity reaction): 169 reports
Eye disorder: 114 reports
Eye pain: 117 reports
Fainting (loss of consciousness and postural tone): 431 reports
Fall: 1,473 reports
Fatigue (feeling of tiredness): 2,909 reports
Febrile neutropenia (fever with reduced white blood cells): 124 reports
Feeling cold: 116 reports
Feeling hot: 168 reports
Fever: 1,072 reports
Flatulence (flatus expelled through the anus): 239 reports
Fluid retention (an abnormal accumulation of fluid in the blood): 197 reports
Full blood count decreased: 190 reports
Gait disturbance: 711 reports
Gallstones (stone formation by bile component): 169 reports
Gamma-glutamyltransferase increased: 205 reports
Gastric disorder (disease of stomach): 163 reports
Gastric ulcer (stomach ulcer): 246 reports
Gastritis (inflammation of stomach): 124 reports
Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 495 reports
Gastrointestinal disorder (functional problems of gastrointestinal tract): 187 reports
Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 471 reports
General physical health deterioration (weak health status): 274 reports
Gout (uric acid crystals building up in the body): 116 reports
Haematochezia (passage of stools containing blood): 157 reports
Haematocrit decreased: 175 reports
Haematuria (presence of blood in urine): 143 reports
Haemoglobin decreased: 609 reports
Haemorrhage (bleeding): 264 reports
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 193 reports
Hair loss: 563 reports
Hallucinations (sensations that appear real but are created by your mind): 231 reports
Headache (pain in head): 1,664 reports
Head injury: 560 reports
Hearing loss: 103 reports
Heart attack: 509 reports
Heart palpitations (feelings or sensations that your heart is pounding or racing): 381 reports
Heart rate decreased: 150 reports
Heart rate increased: 325 reports
Heart rate irregular: 138 reports
Hepatic enzyme increased: 139 reports
Hepatic failure (liver failure): 113 reports
Hepatic steatosis (fatty liver disease): 113 reports
Hepatitis (inflammation of the liver): 110 reports
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 129 reports
Herpes zoster: 235 reports
Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 135 reports
High blood cholesterol: 403 reports
High blood pressure: 2,349 reports
Hip fracture: 123 reports
Hoarseness or changing voice: 240 reports
Hospitalisation: 301 reports
Hot flush (sudden feelings of heat): 165 reports
Hyperglycemia (high blood sugar): 169 reports
Hyperhidrosis (abnormally increased sweating): 367 reports
Hyperkalemia (damage to or disease of the kidney): 446 reports
Hyperlipidaemia (presence of excess lipids in the blood): 124 reports
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 188 reports
Hypersensitivity: 400 reports
Hypoacusis (loss of hearing): 143 reports
Hypoaesthesia (reduced sense of touch or sensation): 557 reports
Hypoglycemia (low blood sugar): 242 reports
Hypokalemia (low potassium): 297 reports
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 284 reports
Hypotension (abnormally low blood pressure): 1,359 reports
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 139 reports
Impaired healing: 101 reports
Indigestion: 381 reports
Infection: 354 reports
Inflammation: 126 reports
Influenza like illness: 186 reports
Injection site erythema (redness at injection site): 111 reports
Injection site haemorrhage (bleeding from injection site): 106 reports
Injection site pain: 251 reports
Injury: 186 reports
Insomnia (sleeplessness): 935 reports
Intentional overdose: 241 reports
International normalised ratio increased: 158 reports
Interstitial lung disease: 286 reports
Interstitial nephritis (inflammation of the kidney): 234 reports
Intestinal obstruction: 160 reports
Irritable bowel syndrome: 106 reports
Itching: 1,011 reports
Jaundice - yellow skin (a yellowish pigmentation of the skin): 117 reports
Joint pain: 1,220 reports
Joint swelling: 555 reports
Kidney stones: 184 reports
Lactic acidosis (low ph in body tissues): 149 reports
Leukocytosis (increased white blood cells): 102 reports
Lip swelling: 102 reports
Liver disorder (liver diseases): 184 reports
Loss of consciousness: 556 reports
Low tissue oxygen: 125 reports
Lung disorder (lung disease): 146 reports
Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 106 reports
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 108 reports
Malaise (a feeling of general discomfort or uneasiness): 1,417 reports
Malignant neoplasm progression (cancer tumour came back): 181 reports
Melaena (the passage of black, tarry stools): 107 reports
Memory loss: 667 reports
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 101 reports
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 112 reports
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 243 reports
Migraine (headache): 142 reports
Mobility decreased (ability to move is reduced): 170 reports
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 113 reports
Multiple myeloma (cancer of the plasma cells): 195 reports
Muscle aches (muscle pain): 630 reports
Muscle spasms (muscle contraction): 700 reports
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 221 reports
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 212 reports
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 165 reports
Nasopharyngitis (inflammation of the nasopharynx): 565 reports
Nausea (feeling of having an urge to vomit): 2,227 reports
Nausea and vomiting: 1,209 reports
Neck pain: 198 reports
Neoplasm malignant (cancer tumour): 114 reports
Nephrogenic anaemia (anaemia due to kidney disease): 437 reports
Nephropathy (damage to or disease of a kidney): 143 reports
Nervousness: 188 reports
Nervous system disorder (a general class of medical conditions affecting the nervous system): 101 reports
Neuralgia (pain in one or more nerves): 108 reports
Neuropathy peripheral (surface nerve damage): 466 reports
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 130 reports
Night sweats (sweating in night): 172 reports
Nosebleed (bleeding from nose): 303 reports
Oedema (fluid collection in tissue): 318 reports
Oedema peripheral (superficial swelling): 932 reports
Oral pain: 154 reports
Oropharyngeal pain: 275 reports
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 154 reports
Osteopenia (a condition where bone mineral density is lower than normal): 103 reports
Osteoporosis (bones weak and more likely to break): 222 reports
Overdose: 499 reports
Oxygen saturation decreased: 152 reports
Pain: 1,578 reports
Pain in extremity: 1,125 reports
Pancreatitis (inflammation of pancreas): 136 reports
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 209 reports
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 430 reports
Pericardial effusion (fluid around the heart): 132 reports
Peripheral swelling: 822 reports
Pleural effusion (water on the lungs): 422 reports
Pneumonia: 1,377 reports
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 202 reports
Pre-existing condition improved: 135 reports
Productive cough: 167 reports
Pruritus generalised (generalized itching): 109 reports
Psoriasis (immune-mediated disease that affects the skin): 141 reports
Pulmonary embolism (blockage of the main artery of the lung): 221 reports
Pulmonary hypertension (increase in blood pressure in the lung artery): 107 reports
Pulmonary oedema (fluid accumulation in the lungs): 304 reports
Rash erythematous (redness of the skin): 129 reports
Rashes (redness): 1,646 reports
Rash macular (small, flat red spots): 121 reports
Rash pruritic (redness with itching): 223 reports
Rectal haemorrhage (bleeding from anus): 231 reports
Red blood cell count decreased: 216 reports
Renal disorder (kidney disease): 293 reports
Renal failure acute (rapid kidney dysfunction): 600 reports
Renal failure chronic (long lasting kidney dysfunction): 127 reports
Renal impairment (severely reduced kidney function): 518 reports
Renal injury (kidney injury): 518 reports
Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 359 reports
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 370 reports
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 238 reports
Rib fracture: 121 reports
Road traffic accident: 145 reports
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 196 reports
Sepsis (a severe blood infection that can lead to organ failure and death): 405 reports
Septic shock (shock due to blood infection): 106 reports
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 289 reports
Sinusitis (inflammation of sinus): 313 reports
Skin blushing/flushing (a sudden reddening of the face, neck): 269 reports
Skin discoloration: 205 reports
Skin disorder (skin disease): 128 reports
Skin exfoliation (removal of the oldest dead skin cells): 219 reports
Skin ulcer: 123 reports
Sleep apnea syndrome: 246 reports
Sleep disorder: 192 reports
Speech disorder: 176 reports
Speech impairment (adult) (inability to speak (adult)): 269 reports
Stable angina (a constant chest pain): 158 reports
Staphylococcal infection (an infection with staphylococcus bacteria): 157 reports
Stomatitis (inflammation of mucous membrane of mouth): 311 reports
Stress and anxiety: 1,026 reports
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 636 reports
Suicidal ideation: 141 reports
Suicide attempt: 195 reports
Surgery: 153 reports
Swallowing difficulty: 397 reports
Swelling: 286 reports
Swelling face: 195 reports
Taste - impaired: 320 reports
The flu (the flu is caused by an influenza virus): 262 reports
Therapeutic response decreased (less preventive response): 113 reports
Therapeutic response unexpected: 145 reports
Throat irritation: 148 reports
Thrombocytopenia (decrease of platelets in blood): 892 reports
Thrombosis (formation of a blood clot inside a blood vessel): 325 reports
Tinnitus (a ringing in the ears): 135 reports
Tooth disorder (tooth disease): 112 reports
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 200 reports
Tremor (trembling or shaking movements in one or more parts of your body): 508 reports
Type 2 diabetes: 135 reports
Upper respiratory tract infection: 158 reports
Urinary incontinence (inability to control the flow of urine and involuntary urination): 133 reports
Urinary tract infection: 793 reports
Urination - painful: 168 reports
Urticaria (rash of round, red welts on the skin that itch intensely): 284 reports
Vision blurred: 402 reports
Visual acuity reduced (reduced clearness of vision): 121 reports
Visual impairment: 297 reports
Weakness: 2,077 reports
Weight decreased: 1,069 reports
Weight increased: 629 reports
Wheezing (a high-pitched whistling sound made while you breath): 157 reports
White blood cell count decreased: 538 reports
White blood cell count increased: 265 reports

All Amlodipine besylate side effects from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

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With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

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