Butazolidin side effects by duration, gender and age - a phase IV clinical study of FDA data

< 1 month:

1. Haemoglobin decreased
2. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)
3. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
4. Acute generalised exanthematous pustulosis (acute febrile drug eruption)
5. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
6. Erysipelas (bacterial skin infection)

1 - 6 months:

1. Cheilitis (infection of lips)

6 - 12 months:

n/a

1 - 2 years:

1. Ankylosing spondylitis (type of arthritis affecting the spine)

2 - 5 years:

n/a

5 - 10 years:

1. Agitation (state of anxiety or nervous excitement)
2. Anaemia (lack of blood)
3. Crohn's disease (condition that causes inflammation of the gastrointestinal tract)

10+ years:

n/a

not specified:

1. Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
2. Drug hypersensitivity
3. Lung neoplasm malignant (cancer tumour of lung)
4. Deafness bilateral
5. Abdominal pain
6. Ankylosing spondylitis (type of arthritis affecting the spine)
7. Drug ineffective
8. Leukocytosis (increased white blood cells)
9. Abdominal discomfort
10. Activated partial thromboplastin time prolonged

female:

1. Drug hypersensitivity
2. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)
3. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
4. Abdominal pain
5. Drug ineffective
6. Abdominal discomfort
7. Acute generalised exanthematous pustulosis (acute febrile drug eruption)
8. Allergy to arthropod sting
9. Anxiety
10. Asthenia (weakness)

male:

1. Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
2. Lung neoplasm malignant (cancer tumour of lung)
3. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
4. Calculus ureteric (stone in ureter)
5. Cat scratch disease (bacterial infection by cat scratch)
6. Cerebral thrombosis (blood clot in brain)
7. Crohn's disease (condition that causes inflammation of the gastrointestinal tract)
8. Diabetes mellitus inadequate control
9. Disseminated tuberculosis
10. Erysipelas (bacterial skin infection)

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

1. Cheilitis (infection of lips)
2. Leukocytosis (increased white blood cells)

30-39:

1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
2. Deafness bilateral
3. Acute pulmonary oedema (sudden deposit of fluid in the lung))
4. Disseminated tuberculosis
5. Drug ineffective
6. Oedema peripheral (superficial swelling)

40-49:

1. Ankylosing spondylitis (type of arthritis affecting the spine)
2. Acute generalised exanthematous pustulosis (acute febrile drug eruption)
3. Anxiety
4. Calculus ureteric (stone in ureter)
5. Drug exposure during pregnancy
6. Hepatosplenomegaly (enlargement of both the liver and the spleen)
7. Liposarcoma (a cancer tumour that arises in fat cells in deep soft tissue)
8. Pulmonary tuberculosis (lungs tuberculosis)

50-59:

1. Lung neoplasm malignant (cancer tumour of lung)
2. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)
3. Abdominal pain
4. Activated partial thromboplastin time prolonged
5. Anaemia (lack of blood)
6. Crohn's disease (condition that causes inflammation of the gastrointestinal tract)
7. Diabetes mellitus inadequate control
8. Hypertension (high blood pressure)

60+:

1. Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
2. Drug hypersensitivity
3. Acute generalised exanthematous pustulosis (acute febrile drug eruption)
4. Asthenia (weakness)
5. Erysipelas (bacterial skin infection)
6. Gingival bleeding (bleeding gums)