Cotempla xr-odt side effects by duration, gender and age - a phase IV clinical study of FDA data


Side effects are reported by people who take Cotempla xr-odt. Common side effects include abdominal pain upper among females and drug ineffective among males.

The phase IV clinical study is created by eHealthMe based on 76 reports from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On May, 28, 2023

76 people who take Cotempla Xr-Odt and have side effects are studied.

What is Cotempla Xr-Odt?

Cotempla xr-odt has active ingredients of methylphenidate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 193 Cotempla xr-odt users for its effectiveness, alternative drugs and more.

Number of Cotempla xr-odt reports submitted per year:

Cotempla xr-odt side effects.

Cotempla Xr-Odt side effects by time on the drug*:

< 1 month:

  1. Pigmentation disorder (disturbances of human skin colour)
  2. Pruritus (severe itching of the skin)
  3. Rash
  4. Abnormal behaviour
  5. Anxiety
  6. Drug ineffective
  7. Abdominal discomfort
  8. Drug effect increased
  9. Dyskinesia (abnormality or impairment of voluntary movement)

1 - 6 months:

  1. Abdominal pain

6 - 12 months:

  1. Disturbance in attention
  2. Trichotillomania (the compulsive urge to pull out (and in some cases, eat) one's own hair leading to noticeable hair loss, distress)

1 - 2 years:

  1. Retching (strong involuntary effort to vomit)

2 - 5 years:


5 - 10 years:


10+ years:


not specified:

  1. Affect lability (emotional incontinence)
  2. Drug ineffective
  3. Abdominal pain upper
  4. Abnormal behaviour
  5. Decreased appetite
  6. Dizziness
  7. Emotional disorder
  8. Headache (pain in head)
  9. Nausea (feeling of having an urge to vomit)
  10. Retching (strong involuntary effort to vomit)

Cotempla Xr-Odt side effects by gender *:


  1. Abdominal pain upper
  2. Abdominal discomfort
  3. Abnormal behaviour
  4. Affect lability (emotional incontinence)
  5. Anxiety
  6. Disturbance in attention
  7. Dizziness
  8. Drug effect prolonged
  9. Drug ineffective
  10. Heart rate increased


  1. Drug ineffective
  2. Affect lability (emotional incontinence)
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Chest pain
  5. Constipation
  6. Dizziness
  7. Drug effect increased
  8. Dyskinesia (abnormality or impairment of voluntary movement)
  9. Dyspnoea (difficult or laboured respiration)
  10. Emotional disorder

Cotempla Xr-Odt side effects by age (0-1 to 60+) *:




  1. Abnormal behaviour
  2. Drug ineffective
  3. Affect lability (emotional incontinence)
  4. Anxiety
  5. Arachnoid cyst
  6. Dizziness
  7. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  8. Impulsive behaviour
  9. Nausea (feeling of having an urge to vomit)
  10. Rash


  1. Abdominal pain
  2. Anxiety
  3. Abdominal pain upper
  4. Affect lability (emotional incontinence)
  5. Arthralgia (joint pain)
  6. Chest pain
  7. Constipation
  8. Dizziness
  9. Drug effect increased
  10. Drug ineffective


  1. Abdominal discomfort
  2. Vomiting









* Approximation only. Some reports may have incomplete information.

Do you take Cotempla xr-odt?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

How the study uses the data?

The study is based on methylphenidate (the active ingredients of Cotempla xr-odt) and Cotempla xr-odt (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

Related studies

Alternative drugs to, pros and cons of Cotempla xr-odt:

All Cotempla xr-odt side effects from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


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