Diclofenac sodium side effects - from FDA reports

Summary

In this review, we analyze Diclofenac sodium side effects by the time on the drug, gender and age of the people who have side effects while taking Diclofenac sodium. The review is based on 19,166 people who have side effects while taking the drug from FDA. The information that eHealthMe analyzes includes:

  • Diclofenac sodium side effects over time
  • (applicable) Diclofenac sodium side effects by gender
  • Diclofenac sodium side effects by age


What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on diclofenac sodium (the active ingredients of Diclofenac sodium) and Diclofenac sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

What is Diclofenac Sodium?

Diclofenac sodium has active ingredients of diclofenac sodium. It is often used in arthritis. (latest outcomes from Diclofenac sodium 20,400 users)

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.


On Feb, 25, 2019

19,166 people who take Diclofenac Sodium are studied.


Number of reports submitted per year:

Diclofenac sodium side effects.

Most common side effects over time *:

< 1 month:
  • Vomiting
  • Melaena (the passage of black, tarry stools)
  • Drug ineffective
  • Urticaria (rash of round, red welts on the skin that itch intensely)
  • Suicide attempt
  • Rash
  • Swelling face
  • Thrombocytopenia (decrease of platelets in blood)
  • Anaphylactic reaction (serious allergic reaction)
  • Pyrexia (fever)
1 - 6 months:
  • Renal failure acute (rapid kidney dysfunction)
  • Asthenia (weakness)
  • Peritoneal haemorrhage (peritoneal bleeding)
  • Rectal haemorrhage (bleeding from anus)
  • White blood cell count decreased
  • Abdominal pain
  • Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  • Pulmonary embolism (blockage of the main artery of the lung)
  • Syncope (loss of consciousness with an inability to maintain postural tone)
  • Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
6 - 12 months:
  • Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  • Pyrexia (fever)
  • Renal failure (kidney dysfunction)
  • Nausea (feeling of having an urge to vomit)
  • Neoplasm malignant (cancer tumour)
  • Thrombocytopenia (decrease of platelets in blood)
  • Dysgeusia (disorder of the sense of taste)
  • Infection parasitic
  • Iron deficiency anaemia
  • Oedema peripheral (superficial swelling)
1 - 2 years:
  • Gamma-glutamyltransferase increased
  • Pericarditis (inflammation of the pericardium)
  • Vomiting
  • Bile duct cancer stage iii
  • Drug ineffective
  • Red blood cell count decreased
  • Unintended pregnancy (unwanted pregnancies as well as those that are mistimed)
  • Anaemia (lack of blood)
  • Infectious mononucleosis (infection usually caused by the epstein-barr virus)
  • Infertility female
2 - 5 years:
  • Pneumonia
  • Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
  • Cerebral infarction (less blood supply to brain resulting tissue damage)
  • Renal failure (kidney dysfunction)
  • Chronic kidney disease
  • Colonic stenosis (abnormal narrowing of colon)
  • Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  • Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
  • Gastritis (inflammation of stomach)
  • Glioblastoma (most common and most aggressive malignant primary brain tumour in humans)
5 - 10 years:
  • Tuberculosis (a bacterial infection by mycobacterium tuberculosis)
  • Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  • Henoch-schonlein purpura (inflammation of the blood vessels in the skin and other body organs)
  • Sepsis (a severe blood infection that can lead to organ failure and death)
  • Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  • Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  • Gastric ulcer (stomach ulcer)
  • Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  • Hyperkalaemia (damage to or disease of the kidney)
  • Renal impairment (severely reduced kidney function)
10+ years:
  • Weight increased
  • Encephalopathy (functioning of the brain is affected by some agent or condition)
  • Gastric perforation (hole in stomach)
  • Gastric ulcer haemorrhage (bleeding ulcer of stomach)
  • Gastrointestinal necrosis (destruction of gastrointestinal organ)
  • Mobility decreased (ability to move is reduced)
  • Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  • Nausea (feeling of having an urge to vomit)
  • Neuropathy peripheral (surface nerve damage)
  • Ovarian cancer (cancer of ovary)
not specified:
  • Vomiting
  • Drug ineffective
  • Weight decreased
  • Pyrexia (fever)
  • White blood cell count decreased
  • Drug hypersensitivity
  • Weight increased
  • Thrombocytopenia (decrease of platelets in blood)
  • Renal failure acute (rapid kidney dysfunction)
  • Pneumonia

Most common side effects by gender *:

female:
  • Vomiting
  • Drug ineffective
  • Weight decreased
  • Drug hypersensitivity
  • Weight increased
  • Pyrexia (fever)
  • Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  • Nausea (feeling of having an urge to vomit)
  • White blood cell count decreased
  • Urinary tract infection
male:
  • Vomiting
  • Weight decreased
  • Death
  • Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  • Rash
  • Weight increased
  • Somnolence (a state of near-sleep, a strong desire for sleep)
  • Nausea (feeling of having an urge to vomit)
  • Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  • Pyrexia (fever)

Most common side effects by age *:

0-1:
  • Renal failure neonatal (kidney failure in baby less than a year)
  • Ventricular septal defect (a hole in the heart, is a common heart defect that's present at birth (congenital))
  • Anaphylactic reaction (serious allergic reaction)
  • Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  • Premature baby
  • Pulmonary hypertension (increase in blood pressure in the lung artery)
  • Urinary tract infection
  • Apgar score low
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Drug ineffective
2-9:
  • Renal failure acute (rapid kidney dysfunction)
  • Vomiting
  • Restlessness (not able to rest)
  • Renal tubular necrosis (death of kidney tubules)
  • Skin discolouration (change of skin colour)
  • Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  • Abasia (inability to walk)
  • Accidental drug intake by child
  • Diarrhoea
  • Influenza
10-19:
  • Vomiting
  • Renal impairment (severely reduced kidney function)
  • Renal failure acute (rapid kidney dysfunction)
  • Linear iga disease (a rare, idiopathic or drug-induced autoimmune blistering disease of skin)
  • Intentional overdose
  • Megacolon (a very dilated colon)
  • Intra-uterine death
  • Nausea (feeling of having an urge to vomit)
  • Swelling face
  • Visual acuity reduced (reduced clearness of vision)
20-29:
  • White blood cell count decreased
  • Hepatic function abnormal
  • Vomiting
  • Pyrexia (fever)
  • Suicide attempt
  • Weight decreased
  • Abdominal pain
  • Melaena (the passage of black, tarry stools)
  • Porphyria acute (acute defect of blood pigment metabolism in which porphyrins are produced in excess, are present in the blood, and are found in the urine)
  • Anaphylactic reaction (serious allergic reaction)
30-39:
  • Vomiting
  • White blood cell count decreased
  • Premature labour
  • Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  • Pyrexia (fever)
  • Suicidal ideation
  • Rash
  • Drug exposure during pregnancy
  • Periorbital oedema (swelling around the eyes)
  • Arthralgia (joint pain)
40-49:
  • Vomiting
  • Pyrexia (fever)
  • Malaise (a feeling of general discomfort or uneasiness)
  • Weight decreased
  • Weight increased
  • Thrombocytopenia (decrease of platelets in blood)
  • Pruritus (severe itching of the skin)
  • Urticaria (rash of round, red welts on the skin that itch intensely)
  • White blood cell count increased
  • Arthralgia (joint pain)
50-59:
  • Vomiting
  • Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  • Drug ineffective
  • Weight decreased
  • Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  • Pyrexia (fever)
  • Nausea (feeling of having an urge to vomit)
  • Weight increased
  • Thrombocytopenia (decrease of platelets in blood)
  • White blood cell count decreased
60+:
  • Vomiting
  • Renal failure acute (rapid kidney dysfunction)
  • Pneumonia
  • Thrombocytopenia (decrease of platelets in blood)
  • White blood cell count decreased
  • Drug ineffective
  • Weight decreased
  • Pyrexia (fever)
  • Death
  • White blood cell count increased

* Approximation only. Some reports may have incomplete information.

Do you take Diclofenac sodium?


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