Eluxadoline side effects by duration, gender and age - a phase IV clinical study of FDA data

< 1 month:

1. Pancreatitis acute (sudden inflammation of pancreas)
2. Abdominal pain
3. Anxiety

1 - 6 months:

1. Bile duct stone

6 - 12 months:

n/a

1 - 2 years:

1. Diarrhoea

2 - 5 years:

n/a

5 - 10 years:

n/a

10+ years:

n/a

not specified:

1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
2. Abdominal distension
3. Abnormal sensation in eye
4. Adverse event
5. Anxiety
6. Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
7. Asthma
8. Back pain
9. Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
10. Death

female:

1. Abdominal pain
2. Abdominal pain upper
3. Anxiety
4. Diarrhoea
5. Drug ineffective
6. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
7. Abdominal distension
8. Abnormal sensation in eye
9. Adverse event
10. Arthralgia (joint pain)

male:

1. Abdominal pain
2. Arthralgia (joint pain)
3. Asthma
4. Back pain
5. Dehydration (dryness resulting from the removal of water)
6. Diarrhoea
7. Irritable bowel syndrome
8. Malignant melanoma (skin cancer rises from melancytes)
9. Pancreatitis acute (sudden inflammation of pancreas)
10. Thrombosis mesenteric vessel (blood clot in mesenteric vein)

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

1. Abdominal pain upper
2. Bile duct stone

30-39:

n/a

40-49:

1. Arthralgia (joint pain)
2. Asthma
3. Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
4. Hepatic cyst

50-59:

1. Abdominal distension
2. Anxiety
3. Pancreatitis acute (sudden inflammation of pancreas)
4. Rash erythematous (redness of the skin)
5. Thrombosis mesenteric vessel (blood clot in mesenteric vein)

60+:

1. Abdominal pain
2. Diarrhoea
3. Drug ineffective
4. Abnormal sensation in eye
5. Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
6. Death
7. Device failure
8. Disease complication
9. Drug hypersensitivity
10. Dry mouth