Impavido side effects by duration, gender and age - a phase IV clinical study of FDA data

< 1 month:

1. Alanine aminotransferase increased
2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
3. Decreased appetite
4. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
5. Abdominal pain

1 - 6 months:

1. Bone marrow failure
2. Asthenia (weakness)
3. Corneal opacity (scarring or clouding of the cornea)
4. Keratitis (eye's cornea, the front part of the eye, becomes inflamed)
5. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)

6 - 12 months:

1. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
2. Squamous cell carcinoma (a cancer of a kind of epithelial cell)

1 - 2 years:

n/a

2 - 5 years:

1. Disease recurrence

5 - 10 years:

n/a

10+ years:

n/a

not specified:

1. Blindness
2. Keratitis (eye's cornea, the front part of the eye, becomes inflamed)
3. Abdominal pain
4. Abdominal pain upper
5. Alanine aminotransferase increased
6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
7. Arthralgia (joint pain)
8. Atonic seizures (minor type of seizure)
9. Blood bilirubin increased
10. Blood creatine increased

female:

1. Abdominal pain
2. Abdominal pain upper
3. Alanine aminotransferase increased
4. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
5. Asthenia (weakness)
6. Atonic seizures (minor type of seizure)
7. Blood creatinine increased
8. Corneal opacity (scarring or clouding of the cornea)
9. Death
10. Dehydration (dryness resulting from the removal of water)

male:

1. Bone marrow failure
2. Blindness
3. Blood bilirubin increased
4. Blood creatine increased
5. Bowen's disease (early stage of skin cancer)
6. Corneal disorder
7. Cough
8. Deafness
9. Decreased appetite
10. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)

0-1:

1. Decreased appetite

2-9:

n/a

10-19:

1. Abdominal pain upper
2. Corneal opacity (scarring or clouding of the cornea)
3. Disease recurrence
4. Keratitis (eye's cornea, the front part of the eye, becomes inflamed)

20-29:

1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
2. Polyuria (production of too much dilute urine)

30-39:

1. Keratitis (eye's cornea, the front part of the eye, becomes inflamed)
2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
3. Corneal disorder
4. Death
5. Drug ineffective

40-49:

1. Bone marrow failure
2. Abdominal pain
3. Deafness

50-59:

1. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
2. Atonic seizures (minor type of seizure)
3. Cough
4. Disease recurrence

60+:

1. Bowen's disease (early stage of skin cancer)
2. Dehydration (dryness resulting from the removal of water)
3. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
4. Disease recurrence
5. Squamous cell carcinoma (a cancer of a kind of epithelial cell)
6. Alanine aminotransferase increased
7. Blindness
8. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
9. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
10. Arthralgia (joint pain)