Isoniazid side effects - from FDA reports


In this review, we analyze Isoniazid side effects by the time on the drug, gender and age of the people who have side effects while taking Isoniazid. The review is based on 12,353 people who have side effects while taking the drug from FDA, and is updated regularly.

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Isoniazid

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. (latest outcomes from Isoniazid 12,654 users)


On Oct, 25, 2018

12,353 people who take Isoniazid are studied.


Number of reports submitted per year:

Isoniazid side effects.

Most common side effects over time *:

< 1 month:
  • Pyrexia (fever)
  • Vomiting
  • Renal failure acute (rapid kidney dysfunction)
  • Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  • Rash
1 - 6 months:
  • Vomiting
  • Hepatitis (inflammation of the liver)
  • Pneumonia
  • Interstitial lung disease
  • Liver disorder (liver diseases)
6 - 12 months:
  • Renal failure (kidney dysfunction)
  • Vomiting
  • Death
  • Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
  • Neutropenia (an abnormally low number of neutrophils)
1 - 2 years:
  • Neoplasm malignant (cancer tumour)
  • Renal failure (kidney dysfunction)
  • Gastrointestinal necrosis (destruction of gastrointestinal organ)
  • Haemorrhage subcutaneous (bleeding from skin)
  • Cataract (clouding of the lens inside the eye)
2 - 5 years:
  • Colitis ulcerative (inflammation of colon with ulcer)
  • Renal impairment (severely reduced kidney function)
  • Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
  • Angioedema (rapid swelling of the dermis)
  • Arthralgia (joint pain)
5 - 10 years:
  • Anaemia (lack of blood)
  • Malignant ascites (a condition in which a person with cancer has an accumulation of fluid in the abdomen)
  • Nausea (feeling of having an urge to vomit)
  • Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
10+ years:
  • Respiratory failure (inadequate gas exchange by the respiratory system)
  • Drug resistance (reduction in effectiveness of a drug)
  • Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  • Weight decreased
not specified:
  • Pyrexia (fever)
  • Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  • Weight decreased
  • Paradoxical drug reaction
  • Thrombocytopenia (decrease of platelets in blood)

Click here to view more results or personalize the results to your gender and age

Most common side effects by gender *:

female:
  • Vomiting
  • Pyrexia (fever)
  • Weight decreased
  • White blood cell count decreased
  • Rash
male:
  • Vomiting
  • Pyrexia (fever)
  • White blood cell count decreased
  • Death
  • Respiratory failure (inadequate gas exchange by the respiratory system)

Click here to view more results or personalize the results to your gender and age

Most common side effects by age *:

0-1:
  • Vomiting
  • Premature baby
  • Drug resistance (reduction in effectiveness of a drug)
  • Trisomy 21 (a chromosomal disorder that results in the presence of an additional third chromosome 21)
  • Paradoxical drug reaction
2-9:
  • Tuberculoma of central nervous system (a tumour-like mass that is not a cancer in brain, a complication of tuberculosis)
  • Drug resistance (reduction in effectiveness of a drug)
  • Acute hepatic failure
  • Optic neuritis (optic nerve inflammation)
  • Ocular icterus (presence of jaundice seen in the sclera of the eye)
10-19:
  • Vomiting
  • Acute hepatic failure
  • Paradoxical drug reaction
  • Tuberculoma of central nervous system (a tumour-like mass that is not a cancer in brain, a complication of tuberculosis)
  • Drug resistance (reduction in effectiveness of a drug)
20-29:
  • Vomiting
  • Pyrexia (fever)
  • Weight decreased
  • Acute hepatic failure
  • Paradoxical drug reaction
30-39:
  • Vomiting
  • Pyrexia (fever)
  • White blood cell count decreased
  • Spermatozoa progressive motility decreased
  • Hepatotoxicity (chemical-driven liver damage)
40-49:
  • Vomiting
  • Pyrexia (fever)
  • Death
  • Transaminases increased
  • Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
50-59:
  • Vomiting
  • Pyrexia (fever)
  • Weight decreased
  • Liver function test abnormal
  • White blood cell count decreased
60+:
  • Vomiting
  • Pneumonia
  • Interstitial lung disease
  • Pyrexia (fever)
  • Hepatic function abnormal

Click here to view more results or personalize the results to your gender and age

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

You are not alone:

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All Isoniazid side effects from A to Z

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On eHealthMe, Isoniazid (isoniazid) is often used to treat tuberculosis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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