Isovue-m 300 side effects by duration, gender and age - a phase IV clinical study of FDA data

< 1 month:

1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
2. Abasia (inability to walk)
3. Hypoaesthesia (reduced sense of touch or sensation)
4. Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
5. Muscle twitching
6. Blood pressure systolic decreased
7. Brain death
8. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
9. Burning sensation
10. Cardiac arrest

1 - 6 months:

n/a

6 - 12 months:

n/a

1 - 2 years:

n/a

2 - 5 years:

n/a

5 - 10 years:

n/a

10+ years:

n/a

not specified:

1. Aggression
2. Contrast media reaction (reaction associated with the use of intravenous contrast material during radiology)
3. Acute circulatory failure (shock)
4. Agitation (state of anxiety or nervous excitement)
5. Apnoea (suspension of external breathing)
6. Blood creatinine increased
7. Renal failure acute (rapid kidney dysfunction)
8. Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
9. Aphasia (damage to the parts of the brain that control language)
10. Back pain

female:

1. Contrast media reaction (reaction associated with the use of intravenous contrast material during radiology)
2. Acute circulatory failure (shock)
3. Aggression
4. Apnoea (suspension of external breathing)
5. Aphasia (damage to the parts of the brain that control language)
6. Blood pressure diastolic increased
7. Blood pressure systolic decreased
8. Blood urea increased
9. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
10. Brain stem ischaemia (condition in which there is insufficient blood flow to the brain to meet metabolic demand)

male:

1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
2. Aggression
3. C-reactive protein increased
4. Cardiac arrest
5. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
6. Clamminess (moist, sticky, and cold to the touch)
7. Disseminated intravascular coagulation (systemic activation of blood coagulation)
8. Drug maladministration
9. Haematocrit decreased
10. Headache (pain in head)

0-1:

1. Acute circulatory failure (shock)

2-9:

n/a

10-19:

n/a

20-29:

1. Apnoea (suspension of external breathing)
2. Blood pressure diastolic increased

30-39:

1. Apnoea (suspension of external breathing)
2. Cardiac arrest

40-49:

1. Aggression
2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
3. Agitation (state of anxiety or nervous excitement)
4. Back pain
5. Blood creatinine increased
6. Blood pressure decreased
7. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
8. Hearing impaired
9. Hypoaesthesia (reduced sense of touch or sensation)

50-59:

1. Contrast media reaction (reaction associated with the use of intravenous contrast material during radiology)
2. Agitation (state of anxiety or nervous excitement)
3. Blood pressure systolic decreased
4. Brain death
5. Drug maladministration
6. Headache (pain in head)

60+:

1. Aphasia (damage to the parts of the brain that control language)
2. Blood creatinine increased
3. Blood urea increased
4. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
5. Brain stem ischaemia (condition in which there is insufficient blood flow to the brain to meet metabolic demand)
6. Burning sensation
7. C-reactive protein increased
8. Cardiac arrest
9. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
10. Confusion