Jynarque side effects by duration, gender and age - a phase IV clinical study of FDA data

Summary:

Side effects are reported by people who take Jynarque. Common side effects include alanine aminotransferase increased among females and alanine aminotransferase increased among males.

The phase IV clinical study is created by eHealthMe based on 70 reports from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On May, 28, 2023

70 people who take Jynarque and have side effects are studied.


What is Jynarque?

Jynarque has active ingredients of tolvaptan. eHealthMe is studying from 71 Jynarque users for its effectiveness, alternative drugs and more.

Number of Jynarque reports submitted per year:

Jynarque side effects.

Jynarque side effects by time on the drug*:

< 1 month:

  1. Rash generalised (rash on most of body parts)
  2. Alanine aminotransferase increased
  3. Arrhythmia (irregular heartbeat)

1 - 6 months:

  1. Aphonia (inability to produce voice)
  2. Liver injury

6 - 12 months:

  1. Abdominal distension
  2. Abdominal pain
  3. Alanine aminotransferase increased
  4. Blindness unilateral
  5. Blood glucose increased

1 - 2 years:

  1. Hepatic enzyme increased

2 - 5 years:

n/a

5 - 10 years:

n/a

10+ years:

n/a

not specified:

  1. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  2. Alanine aminotransferase increased
  3. Blood creatinine increased
  4. Abdominal discomfort
  5. Abdominal distension
  6. Abdominal pain
  7. Adverse drug reaction
  8. Anxiety
  9. Arthralgia (joint pain)
  10. Aspartate aminotransferase increased

Jynarque side effects by gender *:

female:

  1. Alanine aminotransferase increased
  2. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  3. Abdominal distension
  4. Abdominal pain
  5. Adverse drug reaction
  6. Blood creatinine increased
  7. Burning sensation
  8. Contusion (a type of hematoma of tissue in which capillaries)
  9. Decreased appetite
  10. Diarrhoea

male:

  1. Alanine aminotransferase increased
  2. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  3. Balance disorder
  4. Blindness unilateral
  5. Blood creatinine increased
  6. Blood glucose decreased
  7. Blood glucose increased
  8. Blood urine present
  9. Change of bowel habit
  10. Death

Jynarque side effects by age (0-1 to 60+) *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Alanine aminotransferase increased

30-39:

  1. Abdominal pain
  2. Back pain
  3. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

40-49:

  1. Alanine aminotransferase increased
  2. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  3. Arrhythmia (irregular heartbeat)
  4. Aspartate aminotransferase increased
  5. Blood creatinine increased
  6. Decreased appetite
  7. Nephrolithiasis (calculi in the kidneys)
  8. Rash generalised (rash on most of body parts)

50-59:

  1. Abdominal distension
  2. Adverse drug reaction
  3. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

60+:

  1. Abdominal distension
  2. Abdominal pain
  3. Alanine aminotransferase increased
  4. Aphonia (inability to produce voice)
  5. Blindness unilateral
  6. Blood glucose increased
  7. Burning sensation
  8. Change of bowel habit
  9. Fatigue (feeling of tiredness)
  10. Immune system disorder

* Approximation only. Some reports may have incomplete information.

Do you take Jynarque?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



How the study uses the data?

The study is based on tolvaptan (the active ingredients of Jynarque) and Jynarque (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

Related studies

Alternative drugs to, pros and cons of Jynarque:

All Jynarque side effects from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

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