Lamictal side effects - from FDA reports


In this review, we analyze Lamictal side effects by the time on the drug, gender and age of the people who have side effects while taking Lamictal. The review is based on 56,573 people who have side effects while taking the drug from FDA, and is updated regularly.

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Lamictal

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. (latest outcomes from Lamictal 64,115 users)


On Dec, 22, 2018

56,573 people who take Lamictal are studied.


Number of reports submitted per year:

Lamictal side effects.

Most common side effects over time *:

< 1 month:
  • Rash
  • Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  • Vomiting
  • Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  • Rash generalised (rash on most of body parts)
  • Pyrexia (fever)
  • Urticaria (rash of round, red welts on the skin that itch intensely)
  • White blood cell count decreased
  • Toxic skin eruption (skin breakdown due to toxic substance)
  • White blood cell count increased
1 - 6 months:
  • Toxic skin eruption (skin breakdown due to toxic substance)
  • Urticaria (rash of round, red welts on the skin that itch intensely)
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Weight decreased
  • Alopecia (absence of hair from areas of the body)
  • Pruritus (severe itching of the skin)
  • Vision blurred
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • White blood cell count increased
  • Somnolence (a state of near-sleep, a strong desire for sleep)
6 - 12 months:
  • Rash
  • Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  • Ventricular septal defect (a hole in the heart, is a common heart defect that's present at birth (congenital))
  • Vision blurred
  • Vomiting
  • Mania (a state of abnormally elevated or irritable mood)
  • Weight decreased
  • Bone marrow failure
  • Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  • Neonatal respiratory distress syndrome (a serious medical condition where a newborn baby's lungs cannot provide their body with enough oxygen)
1 - 2 years:
  • Rash
  • Urticaria (rash of round, red welts on the skin that itch intensely)
  • Weight decreased
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Weight increased
  • Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Dizziness
  • Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  • Seizure (abnormal excessive or synchronous neuronal activity in the brain)
2 - 5 years:
  • Rash
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Weight increased
  • Cerebral ventricle dilatation (enlargement of ventricle of brain)
  • Somnolence (a state of near-sleep, a strong desire for sleep)
  • Suicidal ideation
  • Thrombocytopenia (decrease of platelets in blood)
  • Alopecia (absence of hair from areas of the body)
  • Optic neuropathy (optic nerve damage)
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
5 - 10 years:
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Pulmonary embolism (blockage of the main artery of the lung)
  • Rash
  • Alopecia (absence of hair from areas of the body)
  • Anxiety
  • Memory impairment
  • Suicidal ideation
  • Urticaria (rash of round, red welts on the skin that itch intensely)
  • Vision blurred
  • Vitamin b12 deficiency
10+ years:
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Drug ineffective
  • Suicidal ideation
  • Therapeutic response unexpected
  • Weight increased
  • Craniocerebral injury (injury to cranium and brain)
  • Depressed mood
  • Depression
  • Dysgraphia (impaired ability to learn to write)
  • Balance disorder
not specified:
  • Rash
  • Weight increased
  • Vomiting
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  • Drug ineffective
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Somnolence (a state of near-sleep, a strong desire for sleep)
  • Weight decreased
  • Suicidal ideation

Most common side effects by gender *:

female:
  • Rash
  • Vomiting
  • Weight increased
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  • Drug ineffective
  • Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  • Weight decreased
  • Somnolence (a state of near-sleep, a strong desire for sleep)
male:
  • Rash
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Suicidal ideation
  • Pyrexia (fever)
  • Vision blurred
  • Death
  • Suicide attempt
  • Nausea (feeling of having an urge to vomit)
  • Insomnia (sleeplessness)
  • Overdose

Most common side effects by age *:

0-1:
  • Ventricular septal defect (a hole in the heart, is a common heart defect that's present at birth (congenital))
  • Premature baby
  • Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Vomiting
  • Weight gain poor
  • Drug exposure during pregnancy
  • Neonatal respiratory distress syndrome (a serious medical condition where a newborn baby's lungs cannot provide their body with enough oxygen)
  • Atrial septal defect (an abnormal opening between the left and right atria of the heart)
  • Viral upper respiratory tract infection
2-9:
  • Rash
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Vomiting
  • Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  • Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
  • Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  • Somnolence (a state of near-sleep, a strong desire for sleep)
  • Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  • Pyrexia (fever)
  • Drug ineffective
10-19:
  • Rash
  • Vomiting
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  • Weight increased
  • Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  • Suicide attempt
  • Weight decreased
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Pyrexia (fever)
20-29:
  • Vomiting
  • Weight increased
  • Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  • Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  • Drug exposure during pregnancy
  • Somnolence (a state of near-sleep, a strong desire for sleep)
  • Suicide attempt
  • Nausea (feeling of having an urge to vomit)
  • Vision blurred
  • Weight decreased
30-39:
  • Rash
  • Vomiting
  • Weight increased
  • Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Suicidal ideation
  • Suicide attempt
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  • Drug exposure during pregnancy
40-49:
  • Rash
  • Weight increased
  • Vomiting
  • Weight decreased
  • Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Drug ineffective
  • Suicidal ideation
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Somnolence (a state of near-sleep, a strong desire for sleep)
50-59:
  • Rash
  • Weight increased
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Vomiting
  • Somnolence (a state of near-sleep, a strong desire for sleep)
  • Weight decreased
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Drug ineffective
  • Suicidal ideation
  • Vision blurred
60+:
  • Rash
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Vomiting
  • Weight decreased
  • Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  • Somnolence (a state of near-sleep, a strong desire for sleep)
  • Weight increased
  • Drug ineffective
  • Pyrexia (fever)
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

You are not alone:

Related studies

All Lamictal side effects from A to Z

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On eHealthMe, Lamictal (lamotrigine) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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